PT1355894E - Derivados de amidinofenilalanina como inibidores de trombina - Google Patents
Derivados de amidinofenilalanina como inibidores de trombinaInfo
- Publication number
- PT1355894E PT1355894E PT01272199T PT01272199T PT1355894E PT 1355894 E PT1355894 E PT 1355894E PT 01272199 T PT01272199 T PT 01272199T PT 01272199 T PT01272199 T PT 01272199T PT 1355894 E PT1355894 E PT 1355894E
- Authority
- PT
- Portugal
- Prior art keywords
- inhibitors
- amidinefenilalanin
- trombine
- derivatives
- compounds
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940122388 Thrombin inhibitor Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003868 thrombin inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
- C07C311/49—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom to nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI200000326A SI20743A (sl) | 2000-12-22 | 2000-12-22 | Novi trombinski inhibitorji |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1355894E true PT1355894E (pt) | 2005-08-31 |
Family
ID=20432799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01272199T PT1355894E (pt) | 2000-12-22 | 2001-12-20 | Derivados de amidinofenilalanina como inibidores de trombina |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7285547B2 (enExample) |
| EP (1) | EP1355894B1 (enExample) |
| JP (1) | JP4390453B2 (enExample) |
| AT (1) | ATE291016T1 (enExample) |
| DE (1) | DE60109498T2 (enExample) |
| DK (1) | DK1355894T3 (enExample) |
| ES (1) | ES2240345T3 (enExample) |
| PT (1) | PT1355894E (enExample) |
| SI (1) | SI20743A (enExample) |
| WO (1) | WO2002051824A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| GB0523539D0 (en) * | 2005-11-18 | 2005-12-28 | Lek Tovarna Farmacevtskih | New use of organic compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9322976D0 (en) * | 1993-11-08 | 1994-01-05 | Pfizer Ltd | Therapeutic agents |
-
2000
- 2000-12-22 SI SI200000326A patent/SI20743A/sl not_active IP Right Cessation
-
2001
- 2001-12-20 AT AT01272199T patent/ATE291016T1/de active
- 2001-12-20 ES ES01272199T patent/ES2240345T3/es not_active Expired - Lifetime
- 2001-12-20 DE DE60109498T patent/DE60109498T2/de not_active Expired - Lifetime
- 2001-12-20 WO PCT/IB2001/002600 patent/WO2002051824A1/en not_active Ceased
- 2001-12-20 US US10/433,358 patent/US7285547B2/en not_active Expired - Fee Related
- 2001-12-20 JP JP2002552919A patent/JP4390453B2/ja not_active Expired - Fee Related
- 2001-12-20 PT PT01272199T patent/PT1355894E/pt unknown
- 2001-12-20 DK DK01272199T patent/DK1355894T3/da active
- 2001-12-20 EP EP01272199A patent/EP1355894B1/en not_active Expired - Lifetime
-
2007
- 2007-09-12 US US11/854,532 patent/US20080004256A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002051824A1 (en) | 2002-07-04 |
| US20080004256A1 (en) | 2008-01-03 |
| DK1355894T3 (da) | 2005-07-11 |
| DE60109498T2 (de) | 2006-04-13 |
| ES2240345T3 (es) | 2005-10-16 |
| EP1355894B1 (en) | 2005-03-16 |
| EP1355894A1 (en) | 2003-10-29 |
| JP4390453B2 (ja) | 2009-12-24 |
| DE60109498D1 (en) | 2005-04-21 |
| ATE291016T1 (de) | 2005-04-15 |
| JP2004516317A (ja) | 2004-06-03 |
| US7285547B2 (en) | 2007-10-23 |
| SI20743A (sl) | 2002-06-30 |
| US20040048851A1 (en) | 2004-03-11 |
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