PT1259229E - Utilizacao de benzotieno-[2,3-d]-pirimidinas com uma accao inibidora da pde v no tratamento do disfuncao erectil - Google Patents
Utilizacao de benzotieno-[2,3-d]-pirimidinas com uma accao inibidora da pde v no tratamento do disfuncao erectilInfo
- Publication number
- PT1259229E PT1259229E PT01909743T PT01909743T PT1259229E PT 1259229 E PT1259229 E PT 1259229E PT 01909743 T PT01909743 T PT 01909743T PT 01909743 T PT01909743 T PT 01909743T PT 1259229 E PT1259229 E PT 1259229E
- Authority
- PT
- Portugal
- Prior art keywords
- pde
- treatment
- benzotieno
- pyrimidines
- utilization
- Prior art date
Links
- 230000001856 erectile effect Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 abstract 2
- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 1
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
- 210000003899 penis Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10010612A DE10010612A1 (de) | 2000-03-03 | 2000-03-03 | Verwendung von PDE V-Inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1259229E true PT1259229E (pt) | 2005-10-31 |
Family
ID=7633516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01909743T PT1259229E (pt) | 2000-03-03 | 2001-02-13 | Utilizacao de benzotieno-[2,3-d]-pirimidinas com uma accao inibidora da pde v no tratamento do disfuncao erectil |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20030022906A1 (pt) |
| EP (1) | EP1259229B1 (pt) |
| JP (1) | JP2004504269A (pt) |
| AT (1) | ATE297719T1 (pt) |
| AU (2) | AU2001237379B2 (pt) |
| CA (1) | CA2401585A1 (pt) |
| CO (1) | CO5210873A1 (pt) |
| DE (2) | DE10010612A1 (pt) |
| ES (1) | ES2241798T3 (pt) |
| MX (1) | MXPA02008571A (pt) |
| PE (1) | PE20011165A1 (pt) |
| PT (1) | PT1259229E (pt) |
| WO (1) | WO2001064192A2 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10031585A1 (de) * | 2000-06-29 | 2002-01-10 | Merck Patent Gmbh | 2-Aminoalkyl-thieno[2,3-d]pyrimidine |
| JPWO2003035653A1 (ja) * | 2001-10-26 | 2005-02-10 | 日本曹達株式会社 | ピリドチエノピリミジン化合物およびその塩 |
| US20050042177A1 (en) * | 2003-07-23 | 2005-02-24 | Elan Pharma International Ltd. | Novel compositions of sildenafil free base |
| CN101778844B (zh) * | 2007-07-26 | 2013-01-02 | 弗·哈夫曼-拉罗切有限公司 | 5-ht2a和d3受体的双重调节剂 |
| CN104945412B (zh) * | 2015-05-26 | 2018-01-23 | 温州医科大学 | 用于FGFR1的四氢苯并噻吩并[2,3‑d]氨基嘧啶衍生物及其制备方法与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9809508A (pt) * | 1997-05-29 | 2000-06-20 | Mochida Pharm Co Ltd | Agente terapêutico para disfunção de ereção |
| US6037346A (en) * | 1997-10-28 | 2000-03-14 | Vivus, Inc. | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
| DE19819023A1 (de) * | 1998-04-29 | 1999-11-04 | Merck Patent Gmbh | Thienopyrimidine |
| US6265420B1 (en) * | 1998-06-23 | 2001-07-24 | Medinox, Inc. | Use of nitric oxide scavengers to treat side effects caused by therapeutic administration of sources of nitric oxide |
| EP1112069A2 (de) * | 1998-08-25 | 2001-07-04 | Alpharma-Isis GmbH & Co. KG | Verwendung von pentaerythritylnitrate zusammen mit phosphodiesterase-v-hemmern, z.b. sildenafil |
| MXPA00003997A (es) * | 1999-04-30 | 2002-03-08 | Lilly Icos Llc | Articulos de fabricacion. |
| DE19928146A1 (de) * | 1999-06-19 | 2000-12-21 | Merck Patent Gmbh | Thienopyrimidine |
| US6476037B1 (en) * | 2000-03-23 | 2002-11-05 | The Regents Of The University Of California | L-arginine and phosphodiesterase (PDE) inhibitor synergism |
-
2000
- 2000-03-03 DE DE10010612A patent/DE10010612A1/de not_active Withdrawn
-
2001
- 2001-02-13 JP JP2001563089A patent/JP2004504269A/ja active Pending
- 2001-02-13 MX MXPA02008571A patent/MXPA02008571A/es unknown
- 2001-02-13 CA CA002401585A patent/CA2401585A1/en not_active Abandoned
- 2001-02-13 US US10/220,416 patent/US20030022906A1/en not_active Abandoned
- 2001-02-13 AT AT01909743T patent/ATE297719T1/de not_active IP Right Cessation
- 2001-02-13 DE DE50106519T patent/DE50106519D1/de not_active Expired - Fee Related
- 2001-02-13 EP EP01909743A patent/EP1259229B1/de not_active Expired - Lifetime
- 2001-02-13 AU AU2001237379A patent/AU2001237379B2/en not_active Ceased
- 2001-02-13 WO PCT/EP2001/001557 patent/WO2001064192A2/de active IP Right Grant
- 2001-02-13 PT PT01909743T patent/PT1259229E/pt unknown
- 2001-02-13 ES ES01909743T patent/ES2241798T3/es not_active Expired - Lifetime
- 2001-02-13 AU AU3737901A patent/AU3737901A/xx active Pending
- 2001-03-01 PE PE2001000209A patent/PE20011165A1/es not_active Application Discontinuation
- 2001-03-02 CO CO01016924A patent/CO5210873A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE10010612A1 (de) | 2001-09-27 |
| WO2001064192A2 (de) | 2001-09-07 |
| JP2004504269A (ja) | 2004-02-12 |
| AU3737901A (en) | 2001-09-12 |
| MXPA02008571A (es) | 2003-02-24 |
| EP1259229B1 (de) | 2005-06-15 |
| CA2401585A1 (en) | 2001-09-07 |
| DE50106519D1 (de) | 2005-07-21 |
| AU2001237379B2 (en) | 2005-05-05 |
| ES2241798T3 (es) | 2005-11-01 |
| ATE297719T1 (de) | 2005-07-15 |
| CO5210873A1 (es) | 2002-10-30 |
| PE20011165A1 (es) | 2001-11-12 |
| WO2001064192A3 (de) | 2001-12-20 |
| EP1259229A2 (de) | 2002-11-27 |
| US20030022906A1 (en) | 2003-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA03005464A (es) | Agentes antivirales. | |
| DK0828728T3 (da) | Phenyldihydrobenzofuraner | |
| TNSN03144A1 (en) | Pyrrolopyrimidines as protein kinase inhibitors | |
| TR200201505T2 (tr) | Terapötik maddeler olarak pirazolopirimidinler | |
| EP1248612A4 (en) | NEW SUBSTANCES AND COMPOUNDS AS PROTEASE INHIBITORS | |
| EA200601654A1 (ru) | Ингибиторы интегразы вич | |
| GEP20053510B (en) | Substituted Pyrrolopyridinone Derivatives Useful as Phosphodiesterase Inhibitors | |
| NO20076219L (no) | Farmasoytisk formulering med apomorfin for bukkal administrering | |
| EE200200107A (et) | Kiire algtoimega selektiivse serotoniini tagasihaaramise inhibiitori kasutamine ravimi valmistamiseks, mis on ette nähtud seksuaalse funktsioonihäireravimiseks | |
| ATE230404T1 (de) | Cyclohexyldihydrobenzofurane | |
| EE200200565A (et) | Vaskulaarse kahjustava toimega kombinatsioonravi | |
| CO5170493A1 (es) | Articulos de fabricacion | |
| AU2020278236A8 (en) | Methods of treating Sjögren's Syndrome using a Bruton's tyrosine kinase inhibitor | |
| WO2001080860A3 (en) | Daily treatment for erectile dysfunction using a pde5 inhibitor | |
| PT1259229E (pt) | Utilizacao de benzotieno-[2,3-d]-pirimidinas com uma accao inibidora da pde v no tratamento do disfuncao erectil | |
| MX2022012310A (es) | Metodos para tratar la esclerosis multiple recidivante con un inhibidor de tirosina quinasa de bruton. | |
| EE05241B1 (et) | Distamtsiini a-halogenoakrlolderivaadi kasutamine | |
| EE200100066A (et) | Naatriumkloriidi kasutamine kamptotetsiini derivaatide manustamisest tingitud gastrointestinaalsetekõrvaltoimete vähendamiseks | |
| HUP0402358A2 (hu) | Szelektív dopamin D4 receptor agonisták alkalmazása szexuális diszfunkciók kezelésére alkalmas gyógyszerkészítmény előállítására | |
| PT1272200E (pt) | Terapeuticas em doses fraccionadas com actividade de degradacao vascular | |
| PT1335730E (pt) | Tratamento da ejaculacao prematura |