PT1228030E - Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco - Google Patents
Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho secoInfo
- Publication number
- PT1228030E PT1228030E PT00971013T PT00971013T PT1228030E PT 1228030 E PT1228030 E PT 1228030E PT 00971013 T PT00971013 T PT 00971013T PT 00971013 T PT00971013 T PT 00971013T PT 1228030 E PT1228030 E PT 1228030E
- Authority
- PT
- Portugal
- Prior art keywords
- methods
- perturbactions
- hydroxyethylate
- treatment
- dry eye
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16437299P | 1999-11-09 | 1999-11-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1228030E true PT1228030E (pt) | 2005-08-31 |
Family
ID=22594195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT00971013T PT1228030E (pt) | 1999-11-09 | 2000-10-23 | Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco |
Country Status (10)
Country | Link |
---|---|
US (1) | US6342525B1 (pt) |
EP (1) | EP1228030B1 (pt) |
JP (1) | JP2003513950A (pt) |
AT (1) | ATE296792T1 (pt) |
AU (1) | AU776153B2 (pt) |
CA (1) | CA2388030A1 (pt) |
DE (1) | DE60020591T2 (pt) |
ES (1) | ES2239621T3 (pt) |
PT (1) | PT1228030E (pt) |
WO (1) | WO2001034552A2 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030109508A1 (en) * | 2001-10-11 | 2003-06-12 | Alcon, Inc. | Methods for treating dry eye |
US20030109488A1 (en) * | 2001-10-11 | 2003-06-12 | Alcon, Inc. | Methods for treating dry eye |
AU2003235454A1 (en) * | 2002-06-14 | 2003-12-31 | Alcon, Inc. | Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders |
AU2003221707A1 (en) * | 2002-06-14 | 2003-12-31 | Alcon, Inc. | Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis |
WO2004026406A1 (en) * | 2002-09-20 | 2004-04-01 | Alcon, Inc. | Use of cytokine synthesis inhibitors for the treatment of dry eye disorders |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3804883A (en) * | 1970-11-02 | 1974-04-16 | Sandoz Ag | 1-(2',4'-disubstituted-6'-omega-substituted-hexyl-1'-phenyl)-1-olefin-3-ones |
US3819694A (en) * | 1971-11-22 | 1974-06-25 | Sandoz Ag | 6-(2-(3-hydroxyalkyl)-3,5-disubstituted-phenyl)hexanoic acids and salts thereof |
US3824278A (en) * | 1972-03-23 | 1974-07-16 | Sandoz Ag | 1,6-disubstituted pyrocatechol derivatives |
US3991759A (en) | 1975-10-28 | 1976-11-16 | Alza Corporation | Method and therapeutic system for treating aqueous deficient dry eye |
US4032656A (en) * | 1975-11-21 | 1977-06-28 | Smithkline Corporation | Aromatic prostaglandin derivatives |
US4131651A (en) | 1977-10-25 | 1978-12-26 | Barnes-Hind Pharmaceuticals, Inc. | Treatment of dry eye |
US4409205A (en) | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
US4370325A (en) | 1979-03-30 | 1983-01-25 | Dermik Laboratories | Pharmaceutical compositions and method of treatment |
AU546872B2 (en) | 1982-06-16 | 1985-09-26 | Unilever Plc | Skin treatment compositions containing a fatty acid or ester |
US4421748A (en) | 1982-07-13 | 1983-12-20 | Trager Seymour F | Artificial tear aid |
GB8319073D0 (en) | 1983-07-14 | 1983-08-17 | Efamol Ltd | Fatty acid compositions |
US4753945A (en) | 1986-02-19 | 1988-06-28 | Eye Research Institute Of Retina Foundation | Stimulation of tear secretion with phosphodiesterase inhibitors |
US4868154A (en) | 1986-02-19 | 1989-09-19 | Eye Research Institute Of Retina Foundation | Stimulation of tear secretion with melanocyte stimulating hormones |
US4744980A (en) | 1986-04-28 | 1988-05-17 | Holly Frank J | Ophthalmic solution for treatment of dry eye syndrome |
US4883658A (en) | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
US4804539A (en) | 1986-07-28 | 1989-02-14 | Liposome Technology, Inc. | Ophthalmic liposomes |
US4818537A (en) | 1986-10-21 | 1989-04-04 | Liposome Technology, Inc. | Liposome composition for treating dry eye |
US4966773A (en) | 1986-11-25 | 1990-10-30 | Alcon Laboratories, Inc. | Topical ophthalmic compositions containing microfine retinoid particles |
US5278151A (en) | 1987-04-02 | 1994-01-11 | Ocular Research Of Boston, Inc. | Dry eye treatment solution |
US4914088A (en) | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
US4921644A (en) | 1988-02-29 | 1990-05-01 | Technology Unlimited, Inc. | Mucin directed lipsome |
US4906467A (en) | 1988-03-24 | 1990-03-06 | New York Medical College | Novel, long-duration treatment for glaucoma |
DE3817385A1 (de) * | 1988-05-19 | 1989-11-30 | Schering Ag | Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4923700A (en) | 1988-06-03 | 1990-05-08 | Kaufman Herbert E | Artificial tear suspension |
US5064655A (en) | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
DE3909327A1 (de) * | 1989-03-17 | 1990-09-20 | Schering Ag | Neue leukotrien-b4-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US5075104A (en) | 1989-03-31 | 1991-12-24 | Alcon Laboratories, Inc. | Ophthalmic carboxy vinyl polymer gel for dry eye syndrome |
US5174988A (en) | 1989-07-27 | 1992-12-29 | Scientific Development & Research, Inc. | Phospholipid delivery system |
JPH05503527A (ja) | 1990-02-22 | 1993-06-10 | マクノート・ピーティーワイ・リミテッド | 人工涙液 |
DE4009117A1 (de) * | 1990-03-19 | 1991-09-26 | Schering Ag | Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US5041434A (en) | 1991-08-17 | 1991-08-20 | Virginia Lubkin | Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application |
ZA912797B (en) | 1990-05-29 | 1992-12-30 | Boston Ocular Res | Dry eye treatment process and solution |
ATE132366T1 (de) | 1990-05-29 | 1996-01-15 | Boston Ocular Res | Zusammensetzung zur behandlung von dry eye erkrankungen |
US5102670A (en) | 1990-09-14 | 1992-04-07 | Abraham Nader G | Method for treating eye disorders by reducing 12(r)-hydroxyeicosatetraenoic acid and 12(r)-dihydroxyeicosatrienoic acid levels |
ATE141502T1 (de) | 1991-01-15 | 1996-09-15 | Alcon Lab Inc | Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen |
ZA927277B (en) | 1991-10-02 | 1993-05-19 | Boston Ocular Res | Dry eye treatment process and solution. |
EP0546728A3 (en) | 1991-12-13 | 1993-09-08 | Alcon Laboratories Inc | Physiological tear compositions and methods for their preparation |
CA2133966C (en) | 1992-04-21 | 1997-09-09 | David A. Sullivan | Ocular androgen therapy in sjogren's syndrome |
US5290572A (en) | 1992-08-06 | 1994-03-01 | Deo Corporation | Opthalmic composition for treating dry eye |
US5358706A (en) | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
US5455265A (en) | 1993-02-11 | 1995-10-03 | Allergan, Inc. | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors |
US5369127A (en) | 1993-04-21 | 1994-11-29 | Allergan, Inc. | 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents |
US5389383A (en) | 1993-06-18 | 1995-02-14 | Allergan, Inc. | Method for treating hypoxia-associated ocular complications |
US5696166A (en) | 1995-10-31 | 1997-12-09 | Yanni; John M. | Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders |
DE69723473T2 (de) | 1996-10-15 | 2004-05-27 | The Liposome Co., Inc. | Peptid-lipid konjugate, liposomen und liposomale arzneimittelverabreichung |
US5800807A (en) | 1997-01-29 | 1998-09-01 | Bausch & Lomb Incorporated | Ophthalmic compositions including glycerin and propylene glycol |
-
2000
- 2000-10-23 DE DE60020591T patent/DE60020591T2/de not_active Expired - Fee Related
- 2000-10-23 EP EP00971013A patent/EP1228030B1/en not_active Expired - Lifetime
- 2000-10-23 CA CA002388030A patent/CA2388030A1/en not_active Abandoned
- 2000-10-23 AU AU80312/00A patent/AU776153B2/en not_active Ceased
- 2000-10-23 WO PCT/US2000/029224 patent/WO2001034552A2/en active Search and Examination
- 2000-10-23 US US09/694,614 patent/US6342525B1/en not_active Expired - Fee Related
- 2000-10-23 JP JP2001536503A patent/JP2003513950A/ja not_active Withdrawn
- 2000-10-23 AT AT00971013T patent/ATE296792T1/de not_active IP Right Cessation
- 2000-10-23 ES ES00971013T patent/ES2239621T3/es not_active Expired - Lifetime
- 2000-10-23 PT PT00971013T patent/PT1228030E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
ES2239621T3 (es) | 2005-10-01 |
DE60020591T2 (de) | 2005-11-10 |
WO2001034552A2 (en) | 2001-05-17 |
US6342525B1 (en) | 2002-01-29 |
AU8031200A (en) | 2001-06-06 |
EP1228030A2 (en) | 2002-08-07 |
JP2003513950A (ja) | 2003-04-15 |
AU776153B2 (en) | 2004-08-26 |
EP1228030B1 (en) | 2005-06-01 |
ATE296792T1 (de) | 2005-06-15 |
DE60020591D1 (de) | 2005-07-07 |
WO2001034552A3 (en) | 2002-01-17 |
CA2388030A1 (en) | 2001-05-17 |
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