PT1194109E - Formulacoes topicas compreendendo agentes de penetracao na pele e utilizacao dasmesmas - Google Patents
Formulacoes topicas compreendendo agentes de penetracao na pele e utilizacao dasmesmasInfo
- Publication number
- PT1194109E PT1194109E PT99973935T PT99973935T PT1194109E PT 1194109 E PT1194109 E PT 1194109E PT 99973935 T PT99973935 T PT 99973935T PT 99973935 T PT99973935 T PT 99973935T PT 1194109 E PT1194109 E PT 1194109E
- Authority
- PT
- Portugal
- Prior art keywords
- comprehending
- skin penetrating
- penetrating agents
- compositions
- formulations
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000000149 penetrating effect Effects 0.000 title 1
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 abstract 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 abstract 2
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 abstract 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229960000541 cetyl alcohol Drugs 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- 150000002009 diols Chemical class 0.000 abstract 1
- 229940075507 glyceryl monostearate Drugs 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 229960003639 laurocapram Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 abstract 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 abstract 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 abstract 1
- 229940012831 stearyl alcohol Drugs 0.000 abstract 1
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14075699P | 1999-06-25 | 1999-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1194109E true PT1194109E (pt) | 2004-12-31 |
Family
ID=22492675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99973935T PT1194109E (pt) | 1999-06-25 | 1999-09-28 | Formulacoes topicas compreendendo agentes de penetracao na pele e utilizacao dasmesmas |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6271219B2 (https=) |
| EP (1) | EP1194109B1 (https=) |
| JP (1) | JP2003506462A (https=) |
| KR (1) | KR100623534B1 (https=) |
| AT (1) | ATE273682T1 (https=) |
| AU (1) | AU769079B2 (https=) |
| BR (1) | BR9917389B1 (https=) |
| CA (1) | CA2376850C (https=) |
| DE (1) | DE69919597T2 (https=) |
| DK (1) | DK1194109T3 (https=) |
| ES (1) | ES2224755T3 (https=) |
| MX (1) | MXPA01013460A (https=) |
| NZ (1) | NZ516765A (https=) |
| PT (1) | PT1194109E (https=) |
| WO (1) | WO2001000139A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006057616A1 (en) * | 2004-11-29 | 2006-06-01 | Ambria Dermatology Ab | A composition comprising at least 3 different diols |
| IL142535A0 (en) * | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
| US8987263B2 (en) | 2002-10-10 | 2015-03-24 | Meir Shinitzky | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents |
| US20050101605A1 (en) * | 2003-11-07 | 2005-05-12 | Ahmed Salah U. | Oral liquid formulations of methotrexate |
| EP2114155A4 (en) | 2007-02-26 | 2014-04-16 | Yeda Res & Dev | AMINO-PHENYL-ACETIC ACID OCTADEC-9- (Z) ENANTIOMERS, THEIR SALTS AND USES THEREOF |
| KR100987121B1 (ko) * | 2010-08-12 | 2010-10-12 | 연세대학교 산학협력단 | 창문닦기로봇 |
| US8809307B2 (en) | 2010-11-22 | 2014-08-19 | Dow Pharmaceutical Sciences, Inc. | Pharmaceutical formulations containing corticosteroids for topical administration |
| US11957753B2 (en) | 2010-11-22 | 2024-04-16 | Bausch Health Ireland Limited | Pharmaceutical formulations containing corticosteroids for topical administration |
| US8853189B2 (en) | 2012-05-31 | 2014-10-07 | Prima Innovations, Llc | Antispasmodic 1,2-Diols and 1,2,3-triols |
| HK1223300A1 (zh) * | 2013-06-03 | 2017-07-28 | Tolmar, Inc. | 皮质类固醇组合物 |
| CN104161721A (zh) * | 2014-07-14 | 2014-11-26 | 湖北博康医药科技有限公司 | 一种用于治疗皮肤病的蛇王药剂及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316893A (en) | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
| BE843140A (fr) | 1975-06-19 | 1976-10-18 | Aazacycloalcan-2-ones 1-substituees et compositions pharmaceutiques contenant ces composes a titre d'excipients | |
| US4444762A (en) | 1980-04-04 | 1984-04-24 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
| US4552872A (en) | 1983-06-21 | 1985-11-12 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing corticosteroids |
| US4557934A (en) | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US4537776A (en) | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
| US4886783A (en) | 1986-01-31 | 1989-12-12 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agents |
| US5196410A (en) * | 1986-10-31 | 1993-03-23 | Pfizer Inc. | Transdermal flux enhancing compositions |
| US4863970A (en) * | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
| JPH0676328B2 (ja) * | 1987-04-14 | 1994-09-28 | 株式会社大塚製薬工場 | ステロイドクリ−ム製剤 |
| DK0437225T3 (da) * | 1990-01-10 | 1994-06-27 | Hoffmann La Roche | Topiske præparater |
| JP3207212B2 (ja) * | 1991-03-01 | 2001-09-10 | 久光製薬株式会社 | 吸収促進剤およびこれを含有する外用剤 |
| US5607691A (en) * | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
| JPH06219947A (ja) * | 1993-01-26 | 1994-08-09 | Kinki Univ | 経皮投与製剤 |
| US5601839A (en) | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
| EP0942697A1 (en) * | 1996-10-30 | 1999-09-22 | THERATECH, INC. (a Delaware Corporation) | Fatty acid esters of lactic acid salts as permeation enhancers |
-
1999
- 1999-09-28 BR BRPI9917389-1A patent/BR9917389B1/pt not_active IP Right Cessation
- 1999-09-28 AT AT99973935T patent/ATE273682T1/de active
- 1999-09-28 WO PCT/US1999/022313 patent/WO2001000139A1/en not_active Ceased
- 1999-09-28 NZ NZ516765A patent/NZ516765A/xx not_active IP Right Cessation
- 1999-09-28 CA CA002376850A patent/CA2376850C/en not_active Expired - Fee Related
- 1999-09-28 PT PT99973935T patent/PT1194109E/pt unknown
- 1999-09-28 AU AU60607/99A patent/AU769079B2/en not_active Ceased
- 1999-09-28 KR KR1020017016610A patent/KR100623534B1/ko not_active Expired - Fee Related
- 1999-09-28 DK DK99973935T patent/DK1194109T3/da active
- 1999-09-28 EP EP99973935A patent/EP1194109B1/en not_active Expired - Lifetime
- 1999-09-28 ES ES99973935T patent/ES2224755T3/es not_active Expired - Lifetime
- 1999-09-28 MX MXPA01013460A patent/MXPA01013460A/es active IP Right Grant
- 1999-09-28 DE DE69919597T patent/DE69919597T2/de not_active Expired - Lifetime
- 1999-09-28 US US09/406,918 patent/US6271219B2/en not_active Expired - Lifetime
- 1999-09-28 JP JP2001515895A patent/JP2003506462A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2376850A1 (en) | 2001-01-04 |
| CA2376850C (en) | 2009-11-17 |
| KR20020038595A (ko) | 2002-05-23 |
| ES2224755T3 (es) | 2005-03-01 |
| US6271219B2 (en) | 2001-08-07 |
| ATE273682T1 (de) | 2004-09-15 |
| KR100623534B1 (ko) | 2006-09-18 |
| JP2003506462A (ja) | 2003-02-18 |
| EP1194109A4 (en) | 2003-01-15 |
| AU769079B2 (en) | 2004-01-15 |
| EP1194109B1 (en) | 2004-08-18 |
| DK1194109T3 (da) | 2004-10-25 |
| DE69919597D1 (de) | 2004-09-23 |
| WO2001000139A1 (en) | 2001-01-04 |
| DE69919597T2 (de) | 2005-07-14 |
| BR9917389A (pt) | 2002-03-05 |
| NZ516765A (en) | 2003-04-29 |
| MXPA01013460A (es) | 2003-09-04 |
| AU6060799A (en) | 2001-01-31 |
| US20010001790A1 (en) | 2001-05-24 |
| EP1194109A1 (en) | 2002-04-10 |
| BR9917389B1 (pt) | 2013-04-24 |
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