BR9608721A - Composição farmacêutica, e, processo para tratar inflamação - Google Patents

Composição farmacêutica, e, processo para tratar inflamação

Info

Publication number
BR9608721A
BR9608721A BR9608721-8A BR9608721A BR9608721A BR 9608721 A BR9608721 A BR 9608721A BR 9608721 A BR9608721 A BR 9608721A BR 9608721 A BR9608721 A BR 9608721A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
metal
treating inflammation
degradation
conditions
Prior art date
Application number
BR9608721-8A
Other languages
English (en)
Inventor
Chong Min Won
Christianna L Strohbeck
Sheng-Yuh Tang
Bih-Hsiung Hsu
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of BR9608721A publication Critical patent/BR9608721A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Colloid Chemistry (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA, E, PROCESSO PARA TRATAR INFLAMAçãO". A degradação de triancinolona acetonida em soluções aquosas é estudada sob condições de armazenagem acelerada de 70‹C sobre a faixa de pH de 1-10. Os íons metálicos a níveis bem baixos podem acelerar fortemente a degradação oxidativa em soluções neutras e básicas, mas as condições de pH e/ou a inclusão de agentes seq³estrantes de metal, tais como acetato de tetra etilenodiamina (EDTA), em uma preparação diminui a catálise de metal.
BR9608721-8A 1995-06-07 1996-06-05 Composição farmacêutica, e, processo para tratar inflamação BR9608721A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48533995A 1995-06-07 1995-06-07
PCT/US1996/009651 WO1996040042A2 (en) 1995-06-07 1996-06-05 Stabilized steroid compositions

Publications (1)

Publication Number Publication Date
BR9608721A true BR9608721A (pt) 1999-10-13

Family

ID=23927770

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9608721-8A BR9608721A (pt) 1995-06-07 1996-06-05 Composição farmacêutica, e, processo para tratar inflamação

Country Status (6)

Country Link
EP (1) EP0843548A4 (pt)
JP (1) JPH11507359A (pt)
AU (1) AU6164196A (pt)
BR (1) BR9608721A (pt)
CA (1) CA2223385A1 (pt)
WO (1) WO1996040042A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
NZ556376A (en) * 2005-02-25 2010-01-29 Chiesi Farma Spa Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent
KR101512284B1 (ko) 2006-12-21 2015-04-15 네르비아노 메디칼 사이언시스 에스.알.엘. 치환된 피라졸로-퀴나졸린 유도체, 이의 제조방법, 및 키나제 억제제로서의 이의 용도
EP3456314A1 (en) 2017-09-14 2019-03-20 Tiofarma B.V. Topical formulation comprising 17-ketolic corticosteroid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344940A (en) * 1981-11-30 1982-08-17 E. R. Squibb & Sons, Inc. Steroid formulation containing dipotassium EDTA
US5542935A (en) * 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
WO1991016034A1 (en) * 1990-04-26 1991-10-31 The Procter & Gamble Company Chelator compositions comprising oxime compounds
KR950000032A (ko) * 1993-06-09 1995-01-03 류경열 맛참기름 제조방법

Also Published As

Publication number Publication date
WO1996040042A3 (en) 1997-02-06
MX9709431A (es) 1998-10-31
JPH11507359A (ja) 1999-06-29
EP0843548A4 (en) 1998-10-28
EP0843548A2 (en) 1998-05-27
AU6164196A (en) 1996-12-30
CA2223385A1 (en) 1996-12-19
WO1996040042A2 (en) 1996-12-19

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law