PT1185253E - Forma de administracao oral para administracao de uma combinacao fixa de tramadol e diclofenac - Google Patents
Forma de administracao oral para administracao de uma combinacao fixa de tramadol e diclofenacInfo
- Publication number
- PT1185253E PT1185253E PT00942052T PT00942052T PT1185253E PT 1185253 E PT1185253 E PT 1185253E PT 00942052 T PT00942052 T PT 00942052T PT 00942052 T PT00942052 T PT 00942052T PT 1185253 E PT1185253 E PT 1185253E
- Authority
- PT
- Portugal
- Prior art keywords
- administration
- diclofenac
- tramadol
- fixed combination
- oral administration
- Prior art date
Links
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 title abstract 2
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001259 diclofenac Drugs 0.000 title abstract 2
- 229960004380 tramadol Drugs 0.000 title abstract 2
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19927689A DE19927689A1 (de) | 1999-06-17 | 1999-06-17 | Orale Darreichungsformen zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1185253E true PT1185253E (pt) | 2004-07-30 |
Family
ID=7911586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00942052T PT1185253E (pt) | 1999-06-17 | 2000-06-13 | Forma de administracao oral para administracao de uma combinacao fixa de tramadol e diclofenac |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20020156133A1 (enExample) |
| EP (1) | EP1185253B1 (enExample) |
| JP (1) | JP4889897B2 (enExample) |
| AT (1) | ATE260650T1 (enExample) |
| AU (1) | AU778151B2 (enExample) |
| CA (1) | CA2377174C (enExample) |
| DE (2) | DE19927689A1 (enExample) |
| DK (1) | DK1185253T3 (enExample) |
| ES (1) | ES2215680T3 (enExample) |
| HK (1) | HK1045113A1 (enExample) |
| HU (1) | HUP0201687A3 (enExample) |
| MX (1) | MXPA01013046A (enExample) |
| NZ (1) | NZ516593A (enExample) |
| PT (1) | PT1185253E (enExample) |
| WO (1) | WO2000078294A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10108122A1 (de) | 2001-02-21 | 2002-10-02 | Gruenenthal Gmbh | Arzneimittel auf Basis von Tramadol |
| US20030134810A1 (en) * | 2001-10-09 | 2003-07-17 | Chris Springate | Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents |
| EP1364649A1 (en) * | 2002-05-23 | 2003-11-26 | Cilag AG | Adduct of topiramate and tramadol hydrochioride and uses thereof |
| EP1628685B1 (en) | 2003-04-25 | 2010-12-08 | Gilead Sciences, Inc. | Antiviral phosphonate analogs |
| US20050265955A1 (en) * | 2004-05-28 | 2005-12-01 | Mallinckrodt Inc. | Sustained release preparations |
| WO2006110157A2 (en) | 2004-07-27 | 2006-10-19 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates as anti hiv agents |
| CN101257894A (zh) | 2005-07-07 | 2008-09-03 | 法纳姆公司 | 高水溶性药物的缓释药物组合物 |
| US20070009591A1 (en) * | 2005-07-07 | 2007-01-11 | Trivedi Jay S | ACE inhibitor formulation |
| EP1785412A1 (en) * | 2005-11-14 | 2007-05-16 | IPCA Laboratories Limited | Tramadol recovery process |
| DE102006006532B4 (de) * | 2006-02-10 | 2007-11-08 | Biogenerics Pharma Gmbh | Pharmazeutische Zubereitung |
| DK2018160T3 (da) | 2006-03-16 | 2012-02-06 | Tris Pharma Inc | Modificeret depotformuleringer indeholdende lægemiddel-ionbytterharpikskomplekser |
| JP2008208078A (ja) * | 2007-02-27 | 2008-09-11 | Takada Seiyaku Kk | 分割錠剤 |
| HRP20120700T1 (hr) | 2008-07-08 | 2012-09-30 | Gilead Sciences | SOLI SPOJEVA INHIBITORA HIV-a |
| DE102008056312A1 (de) | 2008-11-07 | 2010-05-12 | Biogenerics Pharma Gmbh | Verwendung von Mikrotabletten als Lebens-und Futtermittelzusatz |
| KR20130129070A (ko) * | 2010-07-12 | 2013-11-27 | 융신 파마슈티칼 인더스트리얼 컴파니 리미티드 | 트라마돌의 디클로페낙 염 |
| US8623409B1 (en) | 2010-10-20 | 2014-01-07 | Tris Pharma Inc. | Clonidine formulation |
| US8287903B2 (en) | 2011-02-15 | 2012-10-16 | Tris Pharma Inc | Orally effective methylphenidate extended release powder and aqueous suspension product |
| CA2880456A1 (en) | 2012-08-15 | 2014-02-20 | Tris Pharma, Inc. | Methylphenidate extended release chewable tablet |
| US11590228B1 (en) | 2015-09-08 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine compositions |
| ES2892402T3 (es) | 2017-08-01 | 2022-02-04 | Gilead Sciences Inc | Formas cristalinas de ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-il)-4-fluoro-2,5-dihidrofuran-2-il)oxi)metil)(fenoxi)fosforil)-L-alaninato de etilo para tratar infecciones virales |
| US12458592B1 (en) | 2017-09-24 | 2025-11-04 | Tris Pharma, Inc. | Extended release amphetamine tablets |
| US11590081B1 (en) | 2017-09-24 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine tablets |
| CN110755396B (zh) * | 2019-12-06 | 2022-04-08 | 北京悦康科创医药科技股份有限公司 | 一种布洛芬缓释小丸及其制备方法 |
| US11918689B1 (en) | 2020-07-28 | 2024-03-05 | Tris Pharma Inc | Liquid clonidine extended release composition |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8521350D0 (en) * | 1985-08-28 | 1985-10-02 | Euro Celtique Sa | Analgesic composition |
| DE3627423A1 (de) * | 1986-08-13 | 1988-02-18 | Thomae Gmbh Dr K | Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung |
| AU661723B2 (en) * | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| US5919826A (en) * | 1996-10-24 | 1999-07-06 | Algos Pharmaceutical Corporation | Method of alleviating pain |
| DE19732928C2 (de) * | 1997-07-31 | 2000-05-18 | Gruenenthal Gmbh | Verwendung substituierter Imidazolidin-2,4-dion-Verbindungen als Schmerzmittel |
-
1999
- 1999-06-17 DE DE19927689A patent/DE19927689A1/de not_active Ceased
-
2000
- 2000-06-13 PT PT00942052T patent/PT1185253E/pt unknown
- 2000-06-13 ES ES00942052T patent/ES2215680T3/es not_active Expired - Lifetime
- 2000-06-13 WO PCT/EP2000/005386 patent/WO2000078294A2/de not_active Ceased
- 2000-06-13 MX MXPA01013046A patent/MXPA01013046A/es active IP Right Grant
- 2000-06-13 JP JP2001504359A patent/JP4889897B2/ja not_active Expired - Fee Related
- 2000-06-13 DK DK00942052T patent/DK1185253T3/da active
- 2000-06-13 CA CA002377174A patent/CA2377174C/en not_active Expired - Fee Related
- 2000-06-13 AT AT00942052T patent/ATE260650T1/de active
- 2000-06-13 NZ NZ516593A patent/NZ516593A/en not_active IP Right Cessation
- 2000-06-13 DE DE50005529T patent/DE50005529D1/de not_active Expired - Lifetime
- 2000-06-13 EP EP00942052A patent/EP1185253B1/de not_active Expired - Lifetime
- 2000-06-13 AU AU56805/00A patent/AU778151B2/en not_active Ceased
- 2000-06-13 HU HU0201687A patent/HUP0201687A3/hu unknown
- 2000-06-13 HK HK02106641.8A patent/HK1045113A1/zh unknown
-
2001
- 2001-12-17 US US10/016,130 patent/US20020156133A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ516593A (en) | 2003-08-29 |
| ATE260650T1 (de) | 2004-03-15 |
| CA2377174C (en) | 2009-07-28 |
| EP1185253B1 (de) | 2004-03-03 |
| DE19927689A1 (de) | 2000-12-21 |
| DE50005529D1 (de) | 2004-04-08 |
| ES2215680T3 (es) | 2004-10-16 |
| WO2000078294A2 (de) | 2000-12-28 |
| WO2000078294A3 (de) | 2001-03-29 |
| AU778151B2 (en) | 2004-11-18 |
| MXPA01013046A (es) | 2002-06-04 |
| CA2377174A1 (en) | 2000-12-28 |
| DK1185253T3 (da) | 2004-04-05 |
| JP2003502360A (ja) | 2003-01-21 |
| US20020156133A1 (en) | 2002-10-24 |
| HUP0201687A2 (en) | 2002-09-28 |
| JP4889897B2 (ja) | 2012-03-07 |
| HK1045113A1 (zh) | 2002-11-15 |
| HUP0201687A3 (en) | 2005-07-28 |
| AU5680500A (en) | 2001-01-09 |
| EP1185253A2 (de) | 2002-03-13 |
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