PT101446A - Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes. - Google Patents
Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes.Info
- Publication number
- PT101446A PT101446A PT10144694A PT10144694A PT101446A PT 101446 A PT101446 A PT 101446A PT 10144694 A PT10144694 A PT 10144694A PT 10144694 A PT10144694 A PT 10144694A PT 101446 A PT101446 A PT 101446A
- Authority
- PT
- Portugal
- Prior art keywords
- chloramphenicol
- solutions
- solubility
- stability
- increasing
- Prior art date
Links
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 title abstract 6
- 229960005091 chloramphenicol Drugs 0.000 title abstract 6
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229940097362 cyclodextrins Drugs 0.000 title 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 4
- WPRAXAOJIODQJR-UHFFFAOYSA-N 1-(3,4-dimethylphenyl)ethanone Chemical compound CC(=O)C1=CC=C(C)C(C)=C1 WPRAXAOJIODQJR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229910021538 borax Inorganic materials 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004327 boric acid Substances 0.000 abstract 1
- 235000010339 sodium tetraborate Nutrition 0.000 abstract 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT10144694A PT101446B (pt) | 1994-01-24 | 1994-01-24 | Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT10144694A PT101446B (pt) | 1994-01-24 | 1994-01-24 | Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT101446A true PT101446A (pt) | 1995-08-09 |
| PT101446B PT101446B (pt) | 1996-11-29 |
Family
ID=20085362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT10144694A PT101446B (pt) | 1994-01-24 | 1994-01-24 | Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes. |
Country Status (1)
| Country | Link |
|---|---|
| PT (1) | PT101446B (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101549159B (zh) * | 2009-05-25 | 2012-02-29 | 昆明振华制药厂有限公司 | 羟丙基-β-环糊精在氯霉素滴眼剂中的应用及方法 |
-
1994
- 1994-01-24 PT PT10144694A patent/PT101446B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT101446B (pt) | 1996-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19950307 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19960820 |
|
| PC3A | Transfer or assignment |
Owner name: LABORATORIO EDOL - PRODUTOS FARMACEUTICOS, S.A, PT Effective date: 20050802 |
|
| MM4A | Annulment/lapse due to non-payment of fees;searched & examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20100726 |