PT101422B - Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao - Google Patents

Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao Download PDF

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Publication number
PT101422B
PT101422B PT101422A PT10142293A PT101422B PT 101422 B PT101422 B PT 101422B PT 101422 A PT101422 A PT 101422A PT 10142293 A PT10142293 A PT 10142293A PT 101422 B PT101422 B PT 101422B
Authority
PT
Portugal
Prior art keywords
vidarabine
derivative
process according
lipid
liposomal
Prior art date
Application number
PT101422A
Other languages
English (en)
Portuguese (pt)
Other versions
PT101422A (pt
Inventor
Maria Eugenia Meirinhos D Cruz
Carlos Mauricio Goncal Barbosa
Luis Filipe Diniz Cab Caldeira
Original Assignee
Ineti Inst Biotec Q F E Tecnol
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ineti Inst Biotec Q F E Tecnol filed Critical Ineti Inst Biotec Q F E Tecnol
Priority to PT101422A priority Critical patent/PT101422B/pt
Priority to EP95903468A priority patent/EP0731703B1/de
Priority to DE69433137T priority patent/DE69433137T2/de
Priority to PCT/PT1994/000013 priority patent/WO1995015762A1/en
Publication of PT101422A publication Critical patent/PT101422A/pt
Publication of PT101422B publication Critical patent/PT101422B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT101422A 1993-12-06 1993-12-06 Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao PT101422B (pt)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PT101422A PT101422B (pt) 1993-12-06 1993-12-06 Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao
EP95903468A EP0731703B1 (de) 1993-12-06 1994-12-06 Liposomformulierungen enthaltend vidarabin oder seine derivate
DE69433137T DE69433137T2 (de) 1993-12-06 1994-12-06 Liposomformulierungen enthaltend vidarabin oder seine derivate
PCT/PT1994/000013 WO1995015762A1 (en) 1993-12-06 1994-12-06 Liposomal formulations containing vidarabine or its derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT101422A PT101422B (pt) 1993-12-06 1993-12-06 Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao

Publications (2)

Publication Number Publication Date
PT101422A PT101422A (pt) 1995-06-30
PT101422B true PT101422B (pt) 1997-06-30

Family

ID=20085352

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101422A PT101422B (pt) 1993-12-06 1993-12-06 Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao

Country Status (4)

Country Link
EP (1) EP0731703B1 (de)
DE (1) DE69433137T2 (de)
PT (1) PT101422B (de)
WO (1) WO1995015762A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003041681A2 (en) * 2001-11-13 2003-05-22 Celator Technologies, Inc. Lipid carrier compositions with enhanced blood stability
AU2002340670A1 (en) * 2001-11-13 2003-05-26 Celator Technologies, Inc. Lipid carrier compositions and methods for improved drug retention
US9603799B2 (en) * 2013-03-15 2017-03-28 Htd Biosystems Inc. Liposomal vaccine adjuvants and methods of making and using same
CN105232571A (zh) * 2015-09-28 2016-01-13 海南中化联合制药工业股份有限公司 一种单磷酸阿糖腺苷药物组合物
CA3057243A1 (en) 2017-03-23 2018-09-27 Lipid Systems Sp. Z.O.O. High-efficiency encapsulation of hydrophilic compounds in unilamellar liposomes
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders
CN113171347B (zh) * 2021-04-06 2022-11-29 海南锦瑞制药有限公司 注射用单磷酸阿糖腺苷冻干粉针剂的制备方法
CN113173957B (zh) * 2021-04-28 2023-10-27 海南锦瑞制药有限公司 单磷酸阿糖腺苷的合成方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02500360A (ja) * 1986-07-28 1990-02-08 リポソーム　テクノロジー，インコーポレイテッド 粘膜組織上での高い保持力を有するリポソーム
JP3357362B2 (ja) * 1990-12-19 2002-12-16 アドバンスド・マグネティクス・インク 多糖類を用いる治療薬のターゲティング
CA2091152C (en) * 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof

Also Published As

Publication number Publication date
WO1995015762A1 (en) 1995-06-15
EP0731703B1 (de) 2003-09-10
DE69433137T2 (de) 2004-07-08
DE69433137D1 (de) 2003-10-16
EP0731703A1 (de) 1996-09-18
PT101422A (pt) 1995-06-30

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