PL86544B1 - - Google Patents

Description

The subject of the invention is a process for the preparation of alkaline bromo-iodine disinfectant preparations containing as active substances bromo-iodine complex compounds with polyphosphates. The preparations obtained in this way are characterized by good microbicidal properties, especially in relation to acid-resistant bacteria, bacteria producing fat shells and bacteria that produce spores, and very good washing properties. These preparations can be used for washing and disinfection in one working treatment of devices. , apparatuses and devices in the dairy, meat and other branches of the food industry, and for cleaning and disinfecting rooms in agriculture, veterinary medicine, medicine and municipal management. Aqueous solutions of these compounds show an alkaline reaction. There are no known methods of producing this type of preparations, based on complex compounds of bromiodine with polyphosphates. The currently used alkaline disinfectants contain active chlorine in the form of chlorinated lime, hypochlorite, sodium, chloramines and the like. The disadvantages of these known alkaline preparations are: harmful to human and animal health, low effectiveness, strong corrosive action on decontaminated materials, the need to use high temperatures (60-100 ° C). An alkaline washing-disinfecting preparation is also known, but it differs in the method of preparation and the use of other substances for synthesis. Moreover, the alkaline bromo iodine preparations, which are the subject of the invention, are characterized by better washing and disinfecting properties. According to the invention, the method of disinfecting agents consists in producing a polyphosphate-bromide complex as the basic active substance, and optionally adding agents supporting the cleaning and disinfecting action. The above-mentioned bromo-iodine complex with polyphosphates can be characterized by the following formula: Me (P03Me) x - OH ... J - Br ... H - 0 (MePOs) xMe where: Me - an alkali metal atom or hydrogen x = 1-30 and is obtained by treatment with a briniodic complex with nonionic surfactants on polyphosphates at 0-50 ° C. The quantitative ratio of the substrates is no more than 1 grammodule of a bromo-complex compound with surface-active compounds for at least 2 gram-molecules of polyphosphate. The necessary bromodium complex compounds with surfactants are obtained by the action of iodine bromide to a surfactant at 0-60 ° C (optimal - 40 ° C) in amounts not greater than 1 gram of iodine bromide JBr per 2 gram of surfactant. Alkoxylated substances are used as surfactants fatty alcohols, oxyalkylated anines and fatty acid amides, and oxyalkylated phenols and alkylphenols. As substances supporting the cleaning and disinfecting action, the following compounds can be used: alkali salts of alkylarylsulfonic acids, alkali salts of sulfated and oxyalkylated fatty alcohols, carboxymethylcellulose, and others. The following basic chemical reactions take place in the production of alkaline bromo-iodine washing-disinfecting preparations: 1. 2R (OCnH2n) y — O — H + JBr t ± RCOCnH ^ y — OH ...... JBr. ..H — OCOCnHgnJy — R, 2. RtOCnH ^ y — OH ... JBr ... H — O— (CnHjnOJy — R + + 2Me (POsMe) x — OMe + 2H20 - + Me (P08Me) x— —OH ... JBr ... H — 0 (MeP08) xMe + 2R (OC2H2n) y— —OH + 2MeOH. The bond between iodine bromide and polyphosphates has the character of a weak coordination bond. Due to this coordination type of iodine bromide with polyphosphates the preparation retains the chemical activity of the oxidant and its microbicidal properties and loses its properties y negative: such as strong toxic effect on humans and animals, irritating and necrotic effect on the skin and mucous membranes, and highly corrosive effect on plastics. The above structure of complex compounds of iodine bromide with polyphosphates is also indicated by spectroscopic examinations in the field of infrared and nuclear magnetic resonance of model systems and chemical studies involving the combination of iodine bromide in the form of complex compounds with non-ionic compounds of the air. choke active, with various chemical compounds of an alkaline nature. All alkaline substances with the exception of polyphosphates and phosphates cause chemical inactivation and microbicide of iodine bromide. On the other hand, polyphosphates due to the formation of complexes do not inactivate iodine bromide, the content of which in the complex compounds is determined by titration of their aqueous solutions with sodium thiosulphate solution. A 1% solution of polyphosphate and phosphate complexes has a pH of 8 + 9. The iodine bromide complexes obtained according to the invention show good washing properties. Their washing capacity at 30 °, determined on the basis of the measurement of the glass moisture by weight method for contamination with fat and milk protein, depending on the concentration of the complex compound in the aqueous solution, given in ppm of active iodine bromide JBr , is shown in Table 1. Table 1 Concentration of the aqueous solution of the codium bromide complex compound in ppm JBr 150 150 + 0.1% DBSNa Type of soiling of glass plates Food milk with 2% fat and acidity 6, 5—7 ° SH acc. To PN-61 / A- -86003 Food cream with 18% fat and 12 ° SH acidity acc. To PN-70 / A-86050 Milk as above Milk as above Milk as above Washing capacity in% 83.1 80.5 95.2 90.0 99.9 96.8 The thus obtained alkaline bromiodine washes and disinfectants have very good microbicidal properties against acid-resistant bacteria, spore-producing bacteria and fungi. The results of microbiological tests are presented in Tables 2 and 3.86 544 6. TABLE 2 The microbicidal activity (%) of the alkaline bromine preparation in relation to the test strains of bacteria No. 1. 2. 3. 4.. 6. • 7. 8. Type of test organism Salmonella cholerae suis Escherichia coli - hemolytic Pseudomonas aeruginosa Bacillus subtilis Streptococcus faecalis Staphylococcus aureus Erisipelothirx insidiosa Mycobacterium phlei Time X action in min. - 5 Temperature 15-35 ° C Temperature 40 ° C Concentration of the preparation in% 0.25 0.5 99.58 100.0 100.0 100.0 99.69 100.0 100.0 100.0 99.31 99 , 81 100.0 100.0 99.84 100.0 100.0 100.0 99.99 100.0 100.0 100.0 99.94 100.0 100.0 100.0 99.06 100.0 100.0 100.0 + + + + + 16 100.0 1 99.79 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 . 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 + 12 +1 100 100 2 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 . 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 100 100 100 3 100.0 100 . 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 100 100 100 0.25 73.29 90.72 100.0 100.0 99 , 15 100.0 100.0 100.0 95.51 95.91 97.95 100.0 0.5 nu 99.69 99.84 100.0 100.0 100.0 100.0 100.0 100, 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 95 , 76 99.36 99.97 99.60 99.66 99.85 100.0 + + + +4 +2 1 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 . 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 + 3 +1 100.0 100.0 2 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100, 0 100.0 100.0 100.0 100.0 100.0 100.0 3 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100, 0 100.0 100.0 100.0 100.0 100.0 Preparations based on complex compounds of food and in the municipal economy of iodine bromide with polyphosphates can be used and transported. The subject of the invention is presented in the following cleaning and disinfection of milking equipment, apparatuses, examples of implementation: equipment and rooms in many branches of industry - 6586 544 8 Table 3 Microbicidal activity (%) of the alkaline bromiodium preparation in relation to the test fungal strains No. 1. 2. 3. 4.. 6.Type of test microorganism Aspergillus niger Aspergillus fumigatus Oospora lactis Microsporon gypseum Trichohyton mentagrophytes Candida albicans 1 Operating time "in min. Temperature 15-35 ° C Temperature 40 ° C Concentration of the preparation in% 0.25 100.0 100.0 99 , 71 99.10 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 0.5 100.0 100.0 99.13 99.67 100.0 100.0 100.0 100.0 and 100.0 100.0 100.0 100.0 100.0 100.0 100.0 66.95 81.73 84.78 85.21 1 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100. (1 100.0 100.0 100.0 100.0 100.0 100.0 100.0 99.65 100 . 0 100.0 100.0 2 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100, 0 100.0 100.0 100.0 100.0 100.0 3 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100) 100.0 100.0 100.0 0.25 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 . 0 100.0 100.0 100.0 100.0 99.69 100.0 100.0 1 0.5 1 100.0 100.0 100.0 100.0 * 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 ioo, d 94, 26 95.65 96.95 100.0 1 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 2 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100 . 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 1 3 100.0 uoo; r 100.0 100.0 100.0 100.0 100.0 100 , 0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 Example I. In a reactor with an agitated cooling system, mixing 3.2 kg of iodine bromide with 18 kg of poorly hydrated octadecyl alcohol ethoxylate of formula C18H87- (OC2H4) 18-OH, not allowing the temperature to rise above 70 ° C. The liquid obtained is mixed with 5.8 kg of sodium polyphosphate of the formula Na5P3OiO at a temperature not exceeding 70 ° C., and 0.6 kg of sodium bromide is added for stabilization. The thus obtained bromiodine complex can be diluted with water in a weight ratio of 1: 5 to 1: 200 as a washing-disinfecting agent. Example II. 16.8 kg of ethoxylated octadecyl alcohol of formula C18H87 (OC2Hg) 18 — OH with 3.26 kg of iodine bromide at a temperature not exceeding 60 ° C are placed in the reactor and the refrigeration system and the obtained liquid is mixed with 120 kg of sodium tripolyphosphate with formula Na5P8O10. To improve the washing properties of the complex compound obtained, 8.2 kg of sodium dodecylbenzene sulphonate are added and 0.6 kg of sodium bromide are stabilized. The thus obtained bromo-iodine complex is diluted with water in the ratio of 1: 5 to 1: 200 for direct use. Example III. 6.5 kg of iodine bromide and 58 kg of nonylphenol ethoxylated with 8 moles of ethylene oxide are placed in a reactor equipped with an agitator and a cooling system. The liquid obtained is mixed with 116 kg of potassium tripolyphosphate K5P8O10, while maintaining the temperature all the time not higher than 65 ° C. The following auxiliary and stabilizing additives are added to the "bromo-iodine complex" thus obtained: 3.1 kg of potassium laurine sulfuric acid, 1.85 kg of sodium gluconate, 2.28 kg of carboxymethylcellulose and 1.2 kg of potassium bromide. depending on the needs, water is diluted for immediate use in the ratio 1: 5 to 1: 200.86 544 9 ethylene and 1.22 kg of iodine bromide, keeping the temperature at all times not above 60 ° C. Then 17.3 kg of lithium phosphorus Li3PO4, 0.2 kg of lithium bromide LiBr and 0.13 kg of lithium gluconate are added. The preparation obtained in this way, based on a complex compound of iodine bromide with lithium phosphate, is diluted for direct use with water in the ratio 1: 5 to 1: 200, as required. Example 5 In a reactor with a stirrer and a cooling system, 15, 3 kg of laurel alcohol o ethoxylated with 10 moles of ethylene oxide and 1.22 kg of iodine bromide, ensuring that the temperature of the reaction mixture does not exceed 60 ° C. To the thus obtained complex of iodine bromide with surfactant, 20.2 kg are added. sodium tripolyphosphate Na5P8O10 and 9.8 kg sodium phosphorus Na8PO4. 2 kg of sodium dodecylbenzenesulfonate, 3.3 kg of carboxymethylcellulose and 0.25 kg of sodium bromide can be used as stabilizing and supporting additives. in a ratio of 1: 5 to 1: 200. PL

Claims (3)

Claims 1. A method for the production of alkaline bromo iodine washing-disinfecting preparations, characterized by the fact that alkali metal polyphosphates, alkali metal phosphates or a mixture thereof are treated at a temperature of 0-70 ° C with an iodine bromide complex compound with nonionics are surface-active compounds, obtained by the action of iodine bromide JBr on nonionic surfactants at a temperature of 0-70 ° C, in amounts not greater than 1 gram of iodine bromide JBr per 2 gram of compound of surfactant, whereby per 1 gram of the so obtained bromo-iodine complex compound with a surfactant compound, not less than 2 grams of polyphosphate, phosphate or their mixtures are added, and the obtained bromo-iodine complex compounds with polyphosphates stabilize alkali metal or alkaline earth bromides and, optionally, the addition of known performance enhancers e washing-disinfecting preparation. 20 2. The method according to claim A process as claimed in claim 1, characterized in that oxyalkylated fatty alcohols, oxyalkylated fatty acid amines and amides, and oxyalkylated phenols and alkylphenols are used as surfactants. 3. The method according to p. The method of claim 1, characterized in that alkaline salts of alkylarylsulfenic acids, alkali salts of sulfated, oxyalkylated fatty alcohols, carboxymethylcellulose and others are used as agents supporting the washing-disinfecting action of the preparation. PL