PL446053A1 - Sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych i chemosensor do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc - Google Patents

Sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych i chemosensor do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc

Info

Publication number
PL446053A1
PL446053A1 PL446053A PL44605323A PL446053A1 PL 446053 A1 PL446053 A1 PL 446053A1 PL 446053 A PL446053 A PL 446053A PL 44605323 A PL44605323 A PL 44605323A PL 446053 A1 PL446053 A1 PL 446053A1
Authority
PL
Poland
Prior art keywords
pulmonary fibrosis
idiopathic pulmonary
biomarkers
body fluids
mmp
Prior art date
Application number
PL446053A
Other languages
English (en)
Other versions
PL249228B1 (pl
Inventor
Katarzyna Bartołd
Krzysztof Noworyta
Andrzej Ardasiewicz
Piyush Sindhu Sharmaa
Włodzimierz Kutner
Original Assignee
Instytut Chemii Fizycznej Polskiej Akademii Nauk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Chemii Fizycznej Polskiej Akademii Nauk filed Critical Instytut Chemii Fizycznej Polskiej Akademii Nauk
Priority to PL446053A priority Critical patent/PL249228B1/pl
Publication of PL446053A1 publication Critical patent/PL446053A1/pl
Publication of PL249228B1 publication Critical patent/PL249228B1/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/46—Polymerisation initiated by wave energy or particle radiation
    • C08F2/52—Polymerisation initiated by wave energy or particle radiation by electric discharge, e.g. voltolisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
    • G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
    • G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
    • G01N2333/96419—Metalloendopeptidases (3.4.24)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Electrochemistry (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Przedmiotem niniejszego zgłoszenia jest sposób jednoczesnego molekularnego wdrukowania trzech epitopów MIAHDFPGIGHK (SEQ ID NO: 1), HGYPKDIYSS (SEQ ID NO: 2) i FKGNKYWAVQGQNV (SEQ ID NO: 3) w polimerze i osadzenia tego molekularnie wdrukowanego polimeru w postaci cienkiej warstwy na elektrodzie złotej albo na złoconej płytce szklanej, sposób oznaczania białkowego biomarkera MMP-1 idiopatycznego włóknienia płuc w płynach ustrojowych, sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych oraz jednostka rozpoznawania molekularnego do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc.
PL446053A 2023-09-07 2023-09-07 Sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych i chemosensor do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc PL249228B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL446053A PL249228B1 (pl) 2023-09-07 2023-09-07 Sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych i chemosensor do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL446053A PL249228B1 (pl) 2023-09-07 2023-09-07 Sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych i chemosensor do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc

Publications (2)

Publication Number Publication Date
PL446053A1 true PL446053A1 (pl) 2025-03-10
PL249228B1 PL249228B1 (pl) 2026-03-09

Family

ID=94868615

Family Applications (1)

Application Number Title Priority Date Filing Date
PL446053A PL249228B1 (pl) 2023-09-07 2023-09-07 Sposób oznaczania biomarkerów białkowych MMP-1 i SP-A idiopatycznego włóknienia płuc w płynach ustrojowych i chemosensor do selektywnego oznaczania biomarkerów idiopatycznego włóknienia płuc

Country Status (1)

Country Link
PL (1) PL249228B1 (pl)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI796010B (zh) * 2021-11-23 2023-03-11 國立高雄大學 基質金屬蛋白酶-1胜肽拓印導電聚合物及其用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI796010B (zh) * 2021-11-23 2023-03-11 國立高雄大學 基質金屬蛋白酶-1胜肽拓印導電聚合物及其用途

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BARTOLD K ET AL.: "Biosens. Bioelectron. 2022, 208, 114203", MOLECULARLY IMPRINTED POLYMER-BASED EXTENDED-GATE FIELD-EFFECT TRANSISTOR (EG-FET) CHEMOSENSOR FOR SELECTIVE DETERMINATION OF MATRIX METALLOPROTEINASE-1 (MMP-1) PROTEIN. *
LEE M-H ET AL.: "Biosensors. 2022; 12(11):1018", PEPTIDE SELECTION OF MMP-1 FOR ELECTROCHEMICAL SENSING WITH EPITOPE-IMPRINTED POLY(TPARA-CO-EDOT)S. *
MAZZOTTA E ET AL.: "Anal Bioanal Chem. 2022; 414(18): 5165-5200", ELECTROCHEMICAL SENSING OF MACROMOLECULES BASED ON MOLECULARLY IMPRINTED POLYMERS: CHALLENGES, SUCCESSFUL STRATEGIES, AND OPPORTUNITIES. *

Also Published As

Publication number Publication date
PL249228B1 (pl) 2026-03-09

Similar Documents

Publication Publication Date Title
CN112384296B (zh) 用于直接电测量酶活性的装置、系统和方法
WO2002008261A3 (en) Bstp-trans protein and related reagents and methods of use thereof
EP1778874B1 (en) Oncofetal fibronectin as a marker for cervical cancer
CN103898205B (zh) 半胱氨酸蛋白酶抑制剂sn的应用
HRP20231569T1 (hr) Nova protutijela protiv il 13 i njihova upotreba
Hastie et al. Automatically predicting dialogue structure using prosodic features
CN103180732B (zh) 检测抗he4抗体的方法以及诊断和/或预后与he4表达细胞相关的病症的方法
Chai et al. Discovery of potential serum protein biomarkers for lymph node metastasis in oral cancer
JP2003534013A5 (pl)
WO2009028880A3 (en) Biomarker composition for detecting diabetic retinopathy and diagnostic kit therefor
CN107367616B (zh) 一种前列腺特异性抗原检测试剂与试剂盒
CN101088012A (zh) Asc作为结肠直肠癌的标记的用途
Mobed et al. Sensitive recognition of Shiga toxin using biosensor technology: An efficient platform towards bioanalysis of pathogenic bacterial
Rodrigo et al. Clinicopathologic significance of expression of CD44s and CD44v6 isoforms in squamous cell carcinoma of the supraglottic larynx
DE60324331D1 (de) Millisekunden-aktivationsschalter für 7-transmembran-proteine
WO2002008282A3 (en) Bstp-ras/rerg protein and related reagents and methods of use thereof
Tempfer et al. Prognostic value of immunohistochemically detected CD44 expression in patients with carcinoma of the vulva
AU8503898A (en) Monospecific antibody reactive with fibrinogen and fibrinopeptide
CN119060188B (zh) 抗人基质金属蛋白酶9抗体、抗体对和检测试剂盒
CN112858434B (zh) 半胱氨酸蛋白酶抑制剂b检测装置及其制备方法和应用
WO2001042285A3 (en) Extracellular matrix and cell adhesion proteins as well as genes encoding them
JP2006501479A5 (pl)
DK1565490T3 (da) Holo-transcobalamin bindingspartnere og deres anvendelse i cobalamintest
WO2004048529A3 (en) Cell adhesion and extracellular matrix proteins
US8067248B2 (en) Method for diagnosing rheumatoid arthritis via assaying myofibroblast-like synoviocytes for fibroblast activation protein