PL431069A1 - Zestaw do wykrywania wirusa grypy zawierający bufor, linker oraz sekwencję aminokwasową oraz sposób detekcji - Google Patents
Zestaw do wykrywania wirusa grypy zawierający bufor, linker oraz sekwencję aminokwasową oraz sposób detekcjiInfo
- Publication number
- PL431069A1 PL431069A1 PL431069A PL43106919A PL431069A1 PL 431069 A1 PL431069 A1 PL 431069A1 PL 431069 A PL431069 A PL 431069A PL 43106919 A PL43106919 A PL 43106919A PL 431069 A1 PL431069 A1 PL 431069A1
- Authority
- PL
- Poland
- Prior art keywords
- influenza virus
- buffer
- virus detection
- amino acid
- acid sequence
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 6
- 241000712461 unidentified influenza virus Species 0.000 title abstract 6
- 125000003275 alpha amino acid group Chemical group 0.000 title abstract 3
- AWGBEIYZPAXXSX-RWMBFGLXSA-N Met-Leu-Pro Chemical compound CC(C)C[C@@H](C(=O)N1CCC[C@@H]1C(=O)O)NC(=O)[C@H](CCSC)N AWGBEIYZPAXXSX-RWMBFGLXSA-N 0.000 abstract 2
- ZWJKVFAYPLPCQB-UNQGMJICSA-N Phe-Arg-Thr Chemical compound C[C@@H](O)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1ccccc1)C(O)=O ZWJKVFAYPLPCQB-UNQGMJICSA-N 0.000 abstract 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 abstract 1
- 229920001213 Polysorbate 20 Polymers 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 abstract 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- AWDBHOZBRXWRKS-UHFFFAOYSA-N tetrapotassium;iron(6+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+6].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] AWDBHOZBRXWRKS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
Zestaw do wykrywania wirusa grypy zawierający urządzenie pomiarowe oraz bufor charakteryzujący się tym, że bufor zawiera 100 mM TRIS - HCl, 6.2 mM potasu heksacyjanożelazian (II), 6.2 mM. Potasu heksacyjanożelazin (III), 0.1% TWEEN 20 o pH w zakresie od 7,00 do 8.00 a urządzenie pomiarowe zawiera w obudowie mikrokontroler, który poprzez frontend analogowy jest połączony z biosensorem do którego za pomocą linkera o wzorze sumarycznym HSCH2(CH2)8CH2-CO- połączona jest cząsteczka do detekcji wirusa grypy o sekwencji aminokwasowej: Met Leu Pro Phe Arg Thr Asp oraz poprzez interfejs komunikacyjny z hostem PC i bezpośrednio ze wskaźnikami, korzystnie ledowymi. Przedmiotem niniejszego zgłoszenia jest także bufor do detekcji wirusa grypy oraz cząsteczka do detekcji wirusa grypy o sekwencji aminokwasowej: Met Leu Pro Phe Arg Thr Asp. Zgłoszenie obejmuje także linker łączony z wyżej zdefiniowaną cząsteczką oraz sposób detekcji wirusa grypy w próbkach biologicznych albo przemysłowych.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL431069A PL431069A1 (pl) | 2019-09-09 | 2019-09-09 | Zestaw do wykrywania wirusa grypy zawierający bufor, linker oraz sekwencję aminokwasową oraz sposób detekcji |
| EP20863767.8A EP4028765A4 (en) | 2019-09-09 | 2020-09-08 | An influenza virus detection kit comprising a buffer, a linker and an amino acid sequence and a detection method |
| PCT/PL2020/050063 WO2021049961A1 (en) | 2019-09-09 | 2020-09-08 | An influenza virus detection kit comprising a buffer, a linker and an amino acid sequence and a detection method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL431069A PL431069A1 (pl) | 2019-09-09 | 2019-09-09 | Zestaw do wykrywania wirusa grypy zawierający bufor, linker oraz sekwencję aminokwasową oraz sposób detekcji |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL431069A1 true PL431069A1 (pl) | 2021-03-22 |
Family
ID=74866346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL431069A PL431069A1 (pl) | 2019-09-09 | 2019-09-09 | Zestaw do wykrywania wirusa grypy zawierający bufor, linker oraz sekwencję aminokwasową oraz sposób detekcji |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4028765A4 (pl) |
| PL (1) | PL431069A1 (pl) |
| WO (1) | WO2021049961A1 (pl) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013034688A1 (en) * | 2011-09-09 | 2013-03-14 | Danmarks Tekniske Universitet | Biosensor for point-of-care diagnostic and on-site measurements |
| PL223208B1 (pl) * | 2012-07-16 | 2016-10-31 | Univ Gdański | Sposób przygotowania immunoczujnika oraz jego zastosowanie do wykrywania wirusa grypy |
| EP3356823B1 (en) * | 2015-09-28 | 2020-04-22 | Sensdx Sp. z o.o. | A modified bdd substrate and its use as an impedance sensor for detection of biological molecules and a system and method for monitoring pathogens |
| KR101892040B1 (ko) * | 2017-01-25 | 2018-08-27 | 원광대학교산학협력단 | 인플루엔자 a형 바이러스의 h5 아형에 특이적으로 결합하는 펩티드 및 이의 용도 |
-
2019
- 2019-09-09 PL PL431069A patent/PL431069A1/pl unknown
-
2020
- 2020-09-08 EP EP20863767.8A patent/EP4028765A4/en active Pending
- 2020-09-08 WO PCT/PL2020/050063 patent/WO2021049961A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021049961A1 (en) | 2021-03-18 |
| EP4028765A4 (en) | 2023-12-13 |
| EP4028765A1 (en) | 2022-07-20 |
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