PL4288413T3 - Sposób wytwarzania analogu prostaglandyny będącego donorem tlenku azotu - Google Patents

Sposób wytwarzania analogu prostaglandyny będącego donorem tlenku azotu

Info

Publication number
PL4288413T3
PL4288413T3 PL21706850.1T PL21706850T PL4288413T3 PL 4288413 T3 PL4288413 T3 PL 4288413T3 PL 21706850 T PL21706850 T PL 21706850T PL 4288413 T3 PL4288413 T3 PL 4288413T3
Authority
PL
Poland
Prior art keywords
preparation
nitric oxide
prostaglandin analogue
oxide donating
donating prostaglandin
Prior art date
Application number
PL21706850.1T
Other languages
English (en)
Inventor
Nicoletta Almirante
Gael Ronsin
Khalid DIKER
Gilles Gorins
Jonathan COUSIN
Audrey BRUNEAU
Original Assignee
Nicox S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox S.A. filed Critical Nicox S.A.
Publication of PL4288413T3 publication Critical patent/PL4288413T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL21706850.1T 2021-02-03 2021-02-03 Sposób wytwarzania analogu prostaglandyny będącego donorem tlenku azotu PL4288413T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP21706850.1A EP4288413B1 (en) 2021-02-03 2021-02-03 Process for the preparation of a nitric oxide donating prostaglandin analogue
PCT/EP2021/052553 WO2022167070A1 (en) 2021-02-03 2021-02-03 Process for the preparation of a nitric oxide donating prostaglandin analogue

Publications (1)

Publication Number Publication Date
PL4288413T3 true PL4288413T3 (pl) 2025-04-28

Family

ID=74672275

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21706850.1T PL4288413T3 (pl) 2021-02-03 2021-02-03 Sposób wytwarzania analogu prostaglandyny będącego donorem tlenku azotu

Country Status (11)

Country Link
US (1) US20240158345A1 (pl)
EP (1) EP4288413B1 (pl)
JP (1) JP7730912B2 (pl)
CN (1) CN116829537A (pl)
AR (1) AR124724A1 (pl)
CA (1) CA3206721A1 (pl)
ES (1) ES3017242T3 (pl)
HU (1) HUE071098T2 (pl)
PL (1) PL4288413T3 (pl)
TW (1) TW202241390A (pl)
WO (1) WO2022167070A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2964005T3 (es) * 2019-08-05 2024-04-03 Nicox Sa Procedimiento de preparación de un análogo de prostaglandina donador de óxido nítrico
RS66198B1 (sr) * 2022-07-07 2024-12-31 Nicox Sa Industrijski postupak za pripremu heksanske kiseline, 6(nitrooksi)-,(1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(etilamino)-7-okso-2-hepten-1-il]3,5- dihidroksiciklopentil]-1-(2-fenil etil)-2-propen-1-il estra i visoko čistog proizvoda

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR076731A1 (es) 2008-05-09 2011-07-06 Pfizer Prostamidas donadoras de oxido nitrico, uso de los mismos y composiciones farmaceuticas
EP2135860A1 (en) * 2008-06-20 2009-12-23 Sandoz AG Improved process for the production of bimatoprost
WO2016155906A1 (en) 2015-03-31 2016-10-06 Nicox S.A. Nitric oxide donating derivatives of fluprostenol
ES2923623T3 (es) * 2018-02-21 2022-09-29 Nicox Sa Procedimiento para la preparación de un análogo de prostaglandina donante de óxido nítrico
ES2964005T3 (es) * 2019-08-05 2024-04-03 Nicox Sa Procedimiento de preparación de un análogo de prostaglandina donador de óxido nítrico

Also Published As

Publication number Publication date
WO2022167070A1 (en) 2022-08-11
TW202241390A (zh) 2022-11-01
HUE071098T2 (hu) 2025-08-28
CN116829537A (zh) 2023-09-29
ES3017242T3 (en) 2025-05-12
JP2024509051A (ja) 2024-02-29
US20240158345A1 (en) 2024-05-16
EP4288413B1 (en) 2025-01-22
EP4288413C0 (en) 2025-01-22
CA3206721A1 (en) 2022-08-11
EP4288413A1 (en) 2023-12-13
AR124724A1 (es) 2023-04-26
JP7730912B2 (ja) 2025-08-28

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