HUE064405T2 - Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására - Google Patents
Eljárás nitrogén-oxid donor prosztaglandin analóg elõállításáraInfo
- Publication number
- HUE064405T2 HUE064405T2 HUE19189993A HUE19189993A HUE064405T2 HU E064405 T2 HUE064405 T2 HU E064405T2 HU E19189993 A HUE19189993 A HU E19189993A HU E19189993 A HUE19189993 A HU E19189993A HU E064405 T2 HUE064405 T2 HU E064405T2
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- nitric oxide
- prostaglandin analogue
- oxide donating
- donating prostaglandin
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title 2
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19189993.9A EP3772511B1 (en) | 2019-08-05 | 2019-08-05 | Process for the preparation of a nitric oxide donating prostaglandin analogue |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE064405T2 true HUE064405T2 (hu) | 2024-03-28 |
Family
ID=67544113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE19189993A HUE064405T2 (hu) | 2019-08-05 | 2019-08-05 | Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására |
Country Status (9)
Country | Link |
---|---|
US (1) | US20220274924A1 (hu) |
EP (1) | EP3772511B1 (hu) |
JP (1) | JP2022544092A (hu) |
CN (1) | CN114174261A (hu) |
CA (1) | CA3146869A1 (hu) |
ES (1) | ES2964005T3 (hu) |
HU (1) | HUE064405T2 (hu) |
TW (1) | TW202120470A (hu) |
WO (1) | WO2021023693A1 (hu) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2024509051A (ja) * | 2021-02-03 | 2024-02-29 | ニコックス エス.エー. | 一酸化窒素供与プロスタグランジン類似体の調製のための方法 |
EP4303211A1 (en) | 2022-07-07 | 2024-01-10 | Nicox S.A. | Industrial process for the preparation of hexanoic acid, 6(nitrooxy)-,(1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]3,5-dihydroxycyclopentyl]-1-(2-phenyl ethyl)-2-propen-1-yl ester and high pure product |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR076731A1 (es) | 2008-05-09 | 2011-07-06 | Pfizer | Prostamidas donadoras de oxido nitrico, uso de los mismos y composiciones farmaceuticas |
US10280138B2 (en) | 2015-03-31 | 2019-05-07 | Nicox S.A. | Nitric oxide donating derivatives of fluprostenol |
HUE052204T2 (hu) * | 2018-02-21 | 2021-04-28 | Nicox Sa | Eljárás nitrogén-monoxidot leadó prosztaglandin analógok elõállítására |
-
2019
- 2019-08-05 EP EP19189993.9A patent/EP3772511B1/en active Active
- 2019-08-05 HU HUE19189993A patent/HUE064405T2/hu unknown
- 2019-08-05 ES ES19189993T patent/ES2964005T3/es active Active
-
2020
- 2020-08-03 CN CN202080055354.XA patent/CN114174261A/zh active Pending
- 2020-08-03 US US17/631,559 patent/US20220274924A1/en active Pending
- 2020-08-03 WO PCT/EP2020/071766 patent/WO2021023693A1/en active Application Filing
- 2020-08-03 JP JP2022506896A patent/JP2022544092A/ja active Pending
- 2020-08-03 CA CA3146869A patent/CA3146869A1/en active Pending
- 2020-08-03 TW TW109126142A patent/TW202120470A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20220274924A1 (en) | 2022-09-01 |
CA3146869A1 (en) | 2021-02-11 |
EP3772511A1 (en) | 2021-02-10 |
EP3772511C0 (en) | 2023-11-08 |
TW202120470A (zh) | 2021-06-01 |
ES2964005T3 (es) | 2024-04-03 |
WO2021023693A1 (en) | 2021-02-11 |
EP3772511B1 (en) | 2023-11-08 |
JP2022544092A (ja) | 2022-10-17 |
CN114174261A (zh) | 2022-03-11 |
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