HUE064405T2 - Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására - Google Patents

Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására

Info

Publication number
HUE064405T2
HUE064405T2 HUE19189993A HUE19189993A HUE064405T2 HU E064405 T2 HUE064405 T2 HU E064405T2 HU E19189993 A HUE19189993 A HU E19189993A HU E19189993 A HUE19189993 A HU E19189993A HU E064405 T2 HUE064405 T2 HU E064405T2
Authority
HU
Hungary
Prior art keywords
preparation
nitric oxide
prostaglandin analogue
oxide donating
donating prostaglandin
Prior art date
Application number
HUE19189993A
Other languages
English (en)
Inventor
Nicoletta Almirante
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of HUE064405T2 publication Critical patent/HUE064405T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE19189993A 2019-08-05 2019-08-05 Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására HUE064405T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19189993.9A EP3772511B1 (en) 2019-08-05 2019-08-05 Process for the preparation of a nitric oxide donating prostaglandin analogue

Publications (1)

Publication Number Publication Date
HUE064405T2 true HUE064405T2 (hu) 2024-03-28

Family

ID=67544113

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE19189993A HUE064405T2 (hu) 2019-08-05 2019-08-05 Eljárás nitrogén-oxid donor prosztaglandin analóg elõállítására

Country Status (9)

Country Link
US (1) US20220274924A1 (hu)
EP (1) EP3772511B1 (hu)
JP (1) JP2022544092A (hu)
CN (1) CN114174261A (hu)
CA (1) CA3146869A1 (hu)
ES (1) ES2964005T3 (hu)
HU (1) HUE064405T2 (hu)
TW (1) TW202120470A (hu)
WO (1) WO2021023693A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024509051A (ja) * 2021-02-03 2024-02-29 ニコックス エス.エー. 一酸化窒素供与プロスタグランジン類似体の調製のための方法
EP4303211A1 (en) 2022-07-07 2024-01-10 Nicox S.A. Industrial process for the preparation of hexanoic acid, 6(nitrooxy)-,(1s,2e)-3-[(1r,2r,3s,5r)-2-[(2z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]3,5-dihydroxycyclopentyl]-1-(2-phenyl ethyl)-2-propen-1-yl ester and high pure product

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR076731A1 (es) 2008-05-09 2011-07-06 Pfizer Prostamidas donadoras de oxido nitrico, uso de los mismos y composiciones farmaceuticas
US10280138B2 (en) 2015-03-31 2019-05-07 Nicox S.A. Nitric oxide donating derivatives of fluprostenol
HUE052204T2 (hu) * 2018-02-21 2021-04-28 Nicox Sa Eljárás nitrogén-monoxidot leadó prosztaglandin analógok elõállítására

Also Published As

Publication number Publication date
US20220274924A1 (en) 2022-09-01
CA3146869A1 (en) 2021-02-11
EP3772511A1 (en) 2021-02-10
EP3772511C0 (en) 2023-11-08
TW202120470A (zh) 2021-06-01
ES2964005T3 (es) 2024-04-03
WO2021023693A1 (en) 2021-02-11
EP3772511B1 (en) 2023-11-08
JP2022544092A (ja) 2022-10-17
CN114174261A (zh) 2022-03-11

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