PL4263568T3 - Sposoby oczyszczania poddanego ponownemu fałdowaniu białka fuzyjnego peptydu Fc - Google Patents

Sposoby oczyszczania poddanego ponownemu fałdowaniu białka fuzyjnego peptydu Fc

Info

Publication number
PL4263568T3
PL4263568T3 PL21839521.8T PL21839521T PL4263568T3 PL 4263568 T3 PL4263568 T3 PL 4263568T3 PL 21839521 T PL21839521 T PL 21839521T PL 4263568 T3 PL4263568 T3 PL 4263568T3
Authority
PL
Poland
Prior art keywords
refolded
purification
methods
fusion protein
peptide fusion
Prior art date
Application number
PL21839521.8T
Other languages
English (en)
Inventor
Sebastian Damerow
Elisa MIR
László Zoltán BARANYAI
Zoltán SÜTÖ
Original Assignee
Richter Gedeon Nyrt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt. filed Critical Richter Gedeon Nyrt.
Publication of PL4263568T3 publication Critical patent/PL4263568T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/524Thrombopoietin, i.e. C-MPL ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL21839521.8T 2020-12-18 2021-12-17 Sposoby oczyszczania poddanego ponownemu fałdowaniu białka fuzyjnego peptydu Fc PL4263568T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20215581 2020-12-18
PCT/EP2021/086384 WO2022129460A1 (en) 2020-12-18 2021-12-17 Methods for the purification of refolded fc-peptide fusion protein

Publications (1)

Publication Number Publication Date
PL4263568T3 true PL4263568T3 (pl) 2025-11-24

Family

ID=74186426

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21839521.8T PL4263568T3 (pl) 2020-12-18 2021-12-17 Sposoby oczyszczania poddanego ponownemu fałdowaniu białka fuzyjnego peptydu Fc

Country Status (17)

Country Link
US (1) US12540160B2 (pl)
EP (1) EP4263568B1 (pl)
AU (1) AU2021399935A1 (pl)
CA (1) CA3200462A1 (pl)
DK (1) DK4263568T3 (pl)
ES (1) ES3040791T3 (pl)
FI (1) FI4263568T3 (pl)
HR (1) HRP20251064T1 (pl)
HU (1) HUE072796T2 (pl)
LT (1) LT4263568T (pl)
MX (1) MX2023007131A (pl)
PL (1) PL4263568T3 (pl)
PT (1) PT4263568T (pl)
RS (1) RS67191B1 (pl)
SI (1) SI4263568T1 (pl)
SM (1) SMT202500333T1 (pl)
WO (1) WO2022129460A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022234412A1 (en) * 2021-05-03 2022-11-10 Lupin Limited A process for purification of fc-fusion proteins

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3537708A1 (de) 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
DE69934585T2 (de) 1998-07-09 2007-10-25 BaroFold, Inc., Boulder Rückfaltung von protein-aggregaten und einschlussteilchen durch hohen druck
KR100719202B1 (ko) 1998-10-23 2007-05-16 키린-암젠 인코포레이티드 MPl 수용체에 결합하는 화합물 및 이를 함유하는 제약학적 조성물
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
CA2612937C (en) * 2005-07-22 2014-05-06 Amgen Inc. Concentrated protein lyophilates, methods, and uses
EA020621B1 (ru) 2009-06-22 2014-12-30 Амген Инк. Рефолдинг белков с использованием химически контролируемого окислительно-восстановительного состояния
US8940878B2 (en) * 2009-06-25 2015-01-27 Amgen Inc. Capture purification processes for proteins expressed in a non-mammalian system
PT3116891T (pt) * 2014-03-10 2020-05-18 Richter Gedeon Nyrt Purificação de imunoglobulina utilizando passos de pré-limpeza
EP3436473A4 (en) 2016-03-29 2019-10-23 Navya Biologicals Pvt. Ltd. METHOD FOR PURIFYING FC FUSION PROTEINS
ES2988363T3 (es) 2016-06-17 2024-11-20 Hoffmann La Roche Purificación de anticuerpos multiespecíficos
HU231498B1 (hu) 2019-04-04 2024-05-28 Richter Gedeon Nyrt Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelőző flokkulálás alkalmazásával

Also Published As

Publication number Publication date
PT4263568T (pt) 2025-09-23
DK4263568T3 (da) 2025-09-22
FI4263568T3 (fi) 2025-09-25
WO2022129460A1 (en) 2022-06-23
US12540160B2 (en) 2026-02-03
SMT202500333T1 (it) 2025-11-10
CA3200462A1 (en) 2022-06-23
EP4263568A1 (en) 2023-10-25
AU2021399935A1 (en) 2023-06-29
US20240101598A1 (en) 2024-03-28
SI4263568T1 (sl) 2025-10-30
HUE072796T2 (hu) 2025-12-28
ES3040791T3 (en) 2025-11-05
LT4263568T (lt) 2025-09-25
HRP20251064T1 (hr) 2025-11-07
RS67191B1 (sr) 2025-10-31
MX2023007131A (es) 2023-06-27
EP4263568B1 (en) 2025-06-18

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