PL4253376T3 - Sól i postać krystaliczna pochodnej heterocyklicznej zawierającej azot, sposób jej otrzymywania i jej zastosowanie - Google Patents
Sól i postać krystaliczna pochodnej heterocyklicznej zawierającej azot, sposób jej otrzymywania i jej zastosowanieInfo
- Publication number
- PL4253376T3 PL4253376T3 PL21897144.8T PL21897144T PL4253376T3 PL 4253376 T3 PL4253376 T3 PL 4253376T3 PL 21897144 T PL21897144 T PL 21897144T PL 4253376 T3 PL4253376 T3 PL 4253376T3
- Authority
- PL
- Poland
- Prior art keywords
- nitrogen
- salt
- preparation
- application
- crystal form
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011354289 | 2020-11-26 | ||
| CN202111389216 | 2021-11-22 | ||
| PCT/CN2021/133653 WO2022111644A1 (zh) | 2020-11-26 | 2021-11-26 | 含氮杂环类衍生物的盐、晶型及其制备方法和应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4253376T3 true PL4253376T3 (pl) | 2025-12-01 |
Family
ID=81753731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21897144.8T PL4253376T3 (pl) | 2020-11-26 | 2021-11-26 | Sól i postać krystaliczna pochodnej heterocyklicznej zawierającej azot, sposób jej otrzymywania i jej zastosowanie |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20240325394A1 (pl) |
| EP (1) | EP4253376B1 (pl) |
| JP (1) | JP2023551006A (pl) |
| CN (1) | CN116490188B (pl) |
| AU (1) | AU2021386339A1 (pl) |
| CA (1) | CA3200164A1 (pl) |
| ES (1) | ES3048702T3 (pl) |
| HR (1) | HRP20251311T1 (pl) |
| HU (1) | HUE073345T2 (pl) |
| PL (1) | PL4253376T3 (pl) |
| RS (1) | RS67327B1 (pl) |
| SM (1) | SMT202500386T1 (pl) |
| TW (1) | TW202229278A (pl) |
| WO (1) | WO2022111644A1 (pl) |
| ZA (1) | ZA202306437B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115052870B (zh) * | 2020-08-02 | 2024-02-20 | 上海喆邺生物科技有限公司 | 一种芳香类化合物及其在抗肿瘤药物中的应用 |
| AU2021347232A1 (en) | 2020-09-23 | 2023-04-27 | Erasca, Inc. | Tricyclic pyridones and pyrimidones |
| WO2022133345A1 (en) | 2020-12-18 | 2022-06-23 | Erasca, Inc. | Tricyclic pyridones and pyrimidones |
| WO2025242031A1 (zh) * | 2024-05-20 | 2025-11-27 | 上海翰森生物医药科技有限公司 | 吡啶并[2,3-d]嘧啶-2(1H)-酮类衍生物联合用药在治疗和预防肿瘤疾病中的用途 |
| WO2026026942A1 (zh) * | 2024-08-02 | 2026-02-05 | 江苏豪森药业集团有限公司 | 一种含氮杂环类衍生物的制备方法及其中间体 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201992781A1 (ru) * | 2017-05-22 | 2020-04-01 | Эмджен Инк. | Ингибиторы g12c kras и способы их применения |
| MA50077A (fr) * | 2017-09-08 | 2020-07-15 | Amgen Inc | Inhibiteurs de kras g12c et leurs procédés d'utilisation |
| WO2019213516A1 (en) * | 2018-05-04 | 2019-11-07 | Amgen Inc. | Kras g12c inhibitors and methods of using the same |
| ES3060664T3 (en) * | 2018-06-12 | 2026-03-27 | Amgen Inc | Kras g12c inhibitors encompassing a piperazine ring and use thereof in the treatment of cancer |
| AU2020277398B2 (en) * | 2019-05-21 | 2026-01-29 | Amgen Inc. | Solid state forms |
| CN118359609A (zh) * | 2019-05-21 | 2024-07-19 | 益方生物科技(上海)股份有限公司 | 杂环化合物，其制备方法和用途 |
| NZ782284A (en) * | 2019-05-21 | 2024-11-29 | Amgen Inc | Solid state forms |
| KR20220027879A (ko) * | 2019-05-29 | 2022-03-08 | 상하이 한서 바이오메디컬 컴퍼니 리미티드 | 질소 함유 헤테로사이클릭 유도체의 조절제, 이의 제조방법 및 용도 |
| CN112390796B (zh) * | 2019-08-19 | 2023-06-27 | 贝达药业股份有限公司 | Kras g12c抑制剂及其在医药上的应用 |
| CN115175908B (zh) * | 2020-01-13 | 2024-07-23 | 苏州泽璟生物制药股份有限公司 | 芳基或杂芳基并吡啶酮或嘧啶酮类衍生物及其制备方法和应用 |
| WO2021185233A1 (en) * | 2020-03-17 | 2021-09-23 | Jacobio Pharmaceuticals Co., Ltd. | Kras mutant protein inhibitors |
| WO2021236920A1 (en) * | 2020-05-20 | 2021-11-25 | Teva Pharmaceuticals International Gmbh | Solid state forms of amg-510 and process for preparation thereof |
-
2021
- 2021-11-26 HR HRP20251311TT patent/HRP20251311T1/hr unknown
- 2021-11-26 AU AU2021386339A patent/AU2021386339A1/en active Pending
- 2021-11-26 RS RS20251054A patent/RS67327B1/sr unknown
- 2021-11-26 SM SM20250386T patent/SMT202500386T1/it unknown
- 2021-11-26 US US18/254,623 patent/US20240325394A1/en active Pending
- 2021-11-26 TW TW110144262A patent/TW202229278A/zh unknown
- 2021-11-26 CN CN202180076059.7A patent/CN116490188B/zh active Active
- 2021-11-26 PL PL21897144.8T patent/PL4253376T3/pl unknown
- 2021-11-26 HU HUE21897144A patent/HUE073345T2/hu unknown
- 2021-11-26 CA CA3200164A patent/CA3200164A1/en active Pending
- 2021-11-26 EP EP21897144.8A patent/EP4253376B1/en active Active
- 2021-11-26 JP JP2023532420A patent/JP2023551006A/ja active Pending
- 2021-11-26 WO PCT/CN2021/133653 patent/WO2022111644A1/zh not_active Ceased
- 2021-11-26 ES ES21897144T patent/ES3048702T3/es active Active
-
2023
- 2023-06-21 ZA ZA2023/06437A patent/ZA202306437B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021386339A1 (en) | 2023-07-06 |
| WO2022111644A1 (zh) | 2022-06-02 |
| EP4253376C0 (en) | 2025-07-30 |
| EP4253376A1 (en) | 2023-10-04 |
| ES3048702T3 (en) | 2025-12-11 |
| RS67327B1 (sr) | 2025-11-28 |
| US20240325394A1 (en) | 2024-10-03 |
| EP4253376A4 (en) | 2024-12-18 |
| EP4253376B1 (en) | 2025-07-30 |
| CN116490188A (zh) | 2023-07-25 |
| JP2023551006A (ja) | 2023-12-06 |
| HRP20251311T1 (hr) | 2026-02-27 |
| CN116490188B (zh) | 2026-01-30 |
| ZA202306437B (en) | 2025-09-25 |
| AU2021386339A9 (en) | 2025-01-09 |
| HUE073345T2 (hu) | 2026-01-28 |
| SMT202500386T1 (it) | 2025-11-10 |
| TW202229278A (zh) | 2022-08-01 |
| CA3200164A1 (en) | 2022-06-02 |
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