PL422140A1 - Zastosowanie totarolu i kompozycja farmaceutyczna zawierająca totarol - Google Patents
Zastosowanie totarolu i kompozycja farmaceutyczna zawierająca totarolInfo
- Publication number
- PL422140A1 PL422140A1 PL422140A PL42214017A PL422140A1 PL 422140 A1 PL422140 A1 PL 422140A1 PL 422140 A PL422140 A PL 422140A PL 42214017 A PL42214017 A PL 42214017A PL 422140 A1 PL422140 A1 PL 422140A1
- Authority
- PL
- Poland
- Prior art keywords
- totarol
- application
- treatment
- parts
- mass
- Prior art date
Links
- CKZZREIPBTYJEQ-UHFFFAOYSA-N Totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(C)C=C2 CKZZREIPBTYJEQ-UHFFFAOYSA-N 0.000 title abstract 4
- ZRVDANDJSTYELM-FXAWDEMLSA-N totarol Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C)C1=C2C(C(C)C)=C(O)C=C1 ZRVDANDJSTYELM-FXAWDEMLSA-N 0.000 title abstract 4
- 229940074347 totarol Drugs 0.000 title abstract 4
- ZRVDANDJSTYELM-UHFFFAOYSA-N trans-totarol Natural products C1CC2C(C)(C)CCCC2(C)C2=C1C(C(C)C)=C(O)C=C2 ZRVDANDJSTYELM-UHFFFAOYSA-N 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 4
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 235000014655 lactic acid Nutrition 0.000 abstract 2
- 239000004310 lactic acid Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 208000024891 symptom Diseases 0.000 abstract 2
- 206010028116 Mucosal inflammation Diseases 0.000 abstract 1
- 208000032159 Vaginal inflammation Diseases 0.000 abstract 1
- 201000008100 Vaginitis Diseases 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Przedmiotem zgłoszenia jest zastosowanie totarolu do wytwarzania preparatu do leczenia stanów zapalnych błony śluzowej pochwy o podłożu bakteryjnym, do łagodzenia objawów w takim leczeniu oraz do profilaktyki i zapobiegania nawrotom takich stanów zapalnych. Zgłoszenie obejmuje także kompozycję farmaceutyczną do leczenia stanów zapalnych błony śluzowej pochwy o podłożu bakteryjnym, do łagodzenia objawów w takim leczeniu oraz do profilaktyki i zapobiegania nawrotom takich stanów zapalnych, zawierającą od 75 do 95 części masowych pochodnej celulozy, od 0,5 do 5 części masowych kwasu mlekowego, od 0,5 do 5 części masowych polimeru zasadowego, w której stosunek stechiometryczny kwasu mlekowego do polimeru zasadowego zawiera się w granicach od 1:1 do 8:1, i która zawiera totarol w ilości od 0,001 do 5 części masowych jako substancję aktywną.
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL422140A PL236429B1 (pl) | 2017-07-06 | 2017-07-06 | Zastosowanie totarolu do wytwarzania preparatu do leczenia bakteryjnego zakażenia pochwy i kompozycja farmaceutyczna do zastosowania w leczeniu stanów zapalnych pochwy o podłożu bakteryjnym |
CA3066602A CA3066602C (en) | 2017-07-06 | 2018-07-04 | Application of totarol and pharmaceutical composition containing totarol |
PT187657655T PT3648751T (pt) | 2017-07-06 | 2018-07-04 | Aplicação de totarol e composição farmacêutica contendo totarol |
RS20221013A RS63728B1 (sr) | 2017-07-06 | 2018-07-04 | Primena totarola i farmaceutskog sastava koji sadrži totarol |
DK18765765.5T DK3648751T3 (da) | 2017-07-06 | 2018-07-04 | Anvendelse af totarol og farmaceutisk sammensætning indeholdende totarol |
US16/629,005 US11534412B2 (en) | 2017-07-06 | 2018-07-04 | Application of totarol and pharmaceutical composition containing totarol |
MA50979A MA50979B1 (fr) | 2017-07-06 | 2018-07-04 | Application de totarol et composition pharmaceutique contenant du totarol |
ES18765765T ES2929646T3 (es) | 2017-07-06 | 2018-07-04 | Aplicación de totarol y composición farmacéutica que contiene totarol |
EP18765765.5A EP3648751B1 (en) | 2017-07-06 | 2018-07-04 | Application of totarol and pharmaceutical composition containing totarol |
UAA201911771A UA126031C2 (uk) | 2017-07-06 | 2018-07-04 | Застосування тотаролу та фармацевтичної композиції, яка містить тотарол |
SI201830794T SI3648751T1 (sl) | 2017-07-06 | 2018-07-04 | Uporaba totarola in farmacevtski sestavek, ki vsebuje totarol |
MA050980A MA50980A (fr) | 2017-07-06 | 2018-07-04 | Application de totarol et composition pharmaceutique contenant du totarol |
KR1020207003488A KR20200024921A (ko) | 2017-07-06 | 2018-07-04 | 토타롤의 용도 및 토타롤을 함유하는 약제학적 조성물 |
HUE18765765A HUE060300T2 (hu) | 2017-07-06 | 2018-07-04 | Totarol alkalmazása és totarolt tartalmazó gyógyászati készítmény |
HRP20221338TT HRP20221338T1 (hr) | 2017-07-06 | 2018-07-04 | Primjena totarola i farmaceutski pripravak koji sadrži totarol |
RU2020104832A RU2812223C2 (ru) | 2017-07-06 | 2018-07-04 | Применение тотарола и фармацевтическая композиция, содержащая тотарол |
BR112019027839-7A BR112019027839A2 (pt) | 2017-07-06 | 2018-07-04 | aplicação de totarol e composição farmacêutica contendo totarol |
LTEPPCT/PL2018/000066T LT3648751T (lt) | 2017-07-06 | 2018-07-04 | Totarolio naudojimas, ir farmacinė kompozicija, kurios sudėtyje yra totarolio |
PCT/PL2018/000066 WO2019009739A1 (en) | 2017-07-06 | 2018-07-04 | APPLICATION OF TOTAROL AND PHARMACEUTICAL COMPOSITION CONTAINING TOTAROL |
CL2019003720A CL2019003720A1 (es) | 2017-07-06 | 2019-12-18 | Aplicación de totarol y composición farmacéutica que contiene totarol. |
IL271875A IL271875B2 (en) | 2017-07-06 | 2020-01-06 | Preparations containing totarol and their use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL422140A PL236429B1 (pl) | 2017-07-06 | 2017-07-06 | Zastosowanie totarolu do wytwarzania preparatu do leczenia bakteryjnego zakażenia pochwy i kompozycja farmaceutyczna do zastosowania w leczeniu stanów zapalnych pochwy o podłożu bakteryjnym |
Publications (2)
Publication Number | Publication Date |
---|---|
PL422140A1 true PL422140A1 (pl) | 2019-01-14 |
PL236429B1 PL236429B1 (pl) | 2021-01-11 |
Family
ID=63518002
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL422140A PL236429B1 (pl) | 2017-07-06 | 2017-07-06 | Zastosowanie totarolu do wytwarzania preparatu do leczenia bakteryjnego zakażenia pochwy i kompozycja farmaceutyczna do zastosowania w leczeniu stanów zapalnych pochwy o podłożu bakteryjnym |
Country Status (19)
Country | Link |
---|---|
US (1) | US11534412B2 (pl) |
EP (1) | EP3648751B1 (pl) |
KR (1) | KR20200024921A (pl) |
BR (1) | BR112019027839A2 (pl) |
CA (1) | CA3066602C (pl) |
CL (1) | CL2019003720A1 (pl) |
DK (1) | DK3648751T3 (pl) |
ES (1) | ES2929646T3 (pl) |
HR (1) | HRP20221338T1 (pl) |
HU (1) | HUE060300T2 (pl) |
IL (1) | IL271875B2 (pl) |
LT (1) | LT3648751T (pl) |
MA (2) | MA50979B1 (pl) |
PL (1) | PL236429B1 (pl) |
PT (1) | PT3648751T (pl) |
RS (1) | RS63728B1 (pl) |
SI (1) | SI3648751T1 (pl) |
UA (1) | UA126031C2 (pl) |
WO (1) | WO2019009739A1 (pl) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114948891A (zh) * | 2021-06-07 | 2022-08-30 | 南通联亚药业股份有限公司 | 药物组合物 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2083809T3 (pl) * | 2006-11-24 | 2014-09-30 | Dsm Ip Assets Bv | Kompozycja dietetyczna lub farmaceutyczna zawierająca tricykliczne diterpeny do leczenia depresji |
RU2563208C1 (ru) * | 2011-12-15 | 2015-09-20 | Колгейт-Палмолив Компани | Антибактериальная композиция, содержащая тимол и тотарол |
CN106581687A (zh) * | 2016-12-22 | 2017-04-26 | 吉林大学 | 以乳清蛋白为基质的桃柁酚抗菌纳米水凝胶及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL107491B1 (pl) | 1977-10-29 | 1980-02-29 | Przemyslowy Instytut Automatyk | Czujnik dwustrunowy do pomiaru malych przesuniec |
PL201869A1 (pl) | 1977-10-29 | 1979-05-21 | Inst Przemyslu Organiczego | Sposob wytwarzania masy kablowej odpornej na dzialanie termitow |
JP2700071B2 (ja) | 1988-06-10 | 1998-01-19 | 株式会社資生堂 | 抗菌剤及びそれを用いた皮膚外用剤、口腔用組成物 |
PL166898B1 (pl) | 1992-02-13 | 1995-06-30 | Akad Medyczna | Sposób wytwarzania kompleksu metylocelulozy z kwasem mlekowym |
US6534548B1 (en) * | 2001-10-02 | 2003-03-18 | Kimberly-Clark Worldwide, Inc. | Isoprenoid compositions for the inhibition of exoprotein production from gram positive bacteria |
PL194437B1 (pl) | 2002-06-05 | 2007-05-31 | Akademia Medyczna Im Piastow S | Sposób wytwarzania kompleksu na bazie kwasu mlekowego |
NZ530834A (en) | 2004-01-28 | 2007-06-29 | Owen John Catchpole | Near-critical extraction of totarol and/or a product containing totarol |
US20090312279A1 (en) * | 2005-12-23 | 2009-12-17 | Sterilex Technologies, Llc | Antimicrobial compositions |
EP1925301A1 (en) * | 2006-11-24 | 2008-05-28 | DSMIP Assets B.V. | Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders |
JP5471335B2 (ja) | 2009-11-17 | 2014-04-16 | ライオン株式会社 | 口腔バイオフィルム殺菌剤 |
WO2014137231A2 (en) | 2013-03-07 | 2014-09-12 | T2G Biotechnology Limited | Totarol extract formulations and uses thereof |
DE102013108870A1 (de) * | 2013-08-16 | 2015-02-19 | Aimecs Gmbh | Mittel zur Reinigung und zum Schutz von technischen Oberflächen |
CN104027260A (zh) | 2014-06-20 | 2014-09-10 | 广州薇美姿个人护理用品有限公司 | 一种含有桃柘酚的口腔护理用品 |
CN104688810A (zh) | 2014-12-29 | 2015-06-10 | 昆明皕凯科技有限公司 | 一种基于天然植物原料的抗菌组合物及其应用 |
-
2017
- 2017-07-06 PL PL422140A patent/PL236429B1/pl unknown
-
2018
- 2018-07-04 CA CA3066602A patent/CA3066602C/en active Active
- 2018-07-04 UA UAA201911771A patent/UA126031C2/uk unknown
- 2018-07-04 LT LTEPPCT/PL2018/000066T patent/LT3648751T/lt unknown
- 2018-07-04 ES ES18765765T patent/ES2929646T3/es active Active
- 2018-07-04 EP EP18765765.5A patent/EP3648751B1/en active Active
- 2018-07-04 SI SI201830794T patent/SI3648751T1/sl unknown
- 2018-07-04 HU HUE18765765A patent/HUE060300T2/hu unknown
- 2018-07-04 KR KR1020207003488A patent/KR20200024921A/ko not_active Application Discontinuation
- 2018-07-04 BR BR112019027839-7A patent/BR112019027839A2/pt unknown
- 2018-07-04 MA MA50979A patent/MA50979B1/fr unknown
- 2018-07-04 WO PCT/PL2018/000066 patent/WO2019009739A1/en unknown
- 2018-07-04 US US16/629,005 patent/US11534412B2/en active Active
- 2018-07-04 RS RS20221013A patent/RS63728B1/sr unknown
- 2018-07-04 MA MA050980A patent/MA50980A/fr unknown
- 2018-07-04 HR HRP20221338TT patent/HRP20221338T1/hr unknown
- 2018-07-04 PT PT187657655T patent/PT3648751T/pt unknown
- 2018-07-04 DK DK18765765.5T patent/DK3648751T3/da active
-
2019
- 2019-12-18 CL CL2019003720A patent/CL2019003720A1/es unknown
-
2020
- 2020-01-06 IL IL271875A patent/IL271875B2/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2083809T3 (pl) * | 2006-11-24 | 2014-09-30 | Dsm Ip Assets Bv | Kompozycja dietetyczna lub farmaceutyczna zawierająca tricykliczne diterpeny do leczenia depresji |
RU2563208C1 (ru) * | 2011-12-15 | 2015-09-20 | Колгейт-Палмолив Компани | Антибактериальная композиция, содержащая тимол и тотарол |
CN106581687A (zh) * | 2016-12-22 | 2017-04-26 | 吉林大学 | 以乳清蛋白为基质的桃柁酚抗菌纳米水凝胶及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
PL236429B1 (pl) | 2021-01-11 |
RS63728B1 (sr) | 2022-12-30 |
RU2020104832A (ru) | 2021-08-06 |
CA3066602A1 (en) | 2019-01-10 |
KR20200024921A (ko) | 2020-03-09 |
CA3066602C (en) | 2024-01-02 |
HRP20221338T1 (hr) | 2022-12-23 |
IL271875B2 (en) | 2023-02-01 |
HUE060300T2 (hu) | 2023-02-28 |
IL271875A (en) | 2020-02-27 |
UA126031C2 (uk) | 2022-08-03 |
IL271875B (en) | 2022-10-01 |
ES2929646T3 (es) | 2022-12-01 |
WO2019009739A1 (en) | 2019-01-10 |
CL2019003720A1 (es) | 2020-05-22 |
PT3648751T (pt) | 2022-10-20 |
EP3648751B1 (en) | 2022-09-28 |
DK3648751T3 (da) | 2022-11-21 |
US20200289429A1 (en) | 2020-09-17 |
RU2020104832A3 (pl) | 2021-10-08 |
MA50979A (fr) | 2020-10-14 |
MA50979B1 (fr) | 2022-11-30 |
MA50980A (fr) | 2020-10-14 |
BR112019027839A2 (pt) | 2020-07-07 |
LT3648751T (lt) | 2022-12-12 |
SI3648751T1 (sl) | 2023-03-31 |
WO2019009739A4 (en) | 2019-02-28 |
EP3648751A1 (en) | 2020-05-13 |
US11534412B2 (en) | 2022-12-27 |
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