PL4185292T3 - Białka s100 jako nowe cele terapeutyczne w przypadku nowotworów mieloproliferacyjnych - Google Patents

Białka s100 jako nowe cele terapeutyczne w przypadku nowotworów mieloproliferacyjnych

Info

Publication number
PL4185292T3
PL4185292T3 PL21749566.2T PL21749566T PL4185292T3 PL 4185292 T3 PL4185292 T3 PL 4185292T3 PL 21749566 T PL21749566 T PL 21749566T PL 4185292 T3 PL4185292 T3 PL 4185292T3
Authority
PL
Poland
Prior art keywords
proteins
therapeutic targets
novel therapeutic
myeloproliferative neoplasms
myeloproliferative
Prior art date
Application number
PL21749566.2T
Other languages
English (en)
Inventor
Rebekka Katharina Marita SCHNEIDER-KRAMANN
Original Assignee
Erasmus University Medical Center Rotterdam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erasmus University Medical Center Rotterdam filed Critical Erasmus University Medical Center Rotterdam
Publication of PL4185292T3 publication Critical patent/PL4185292T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
PL21749566.2T 2020-07-23 2021-07-23 Białka s100 jako nowe cele terapeutyczne w przypadku nowotworów mieloproliferacyjnych PL4185292T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20187323 2020-07-23
PCT/EP2021/070629 WO2022018240A1 (en) 2020-07-23 2021-07-23 S100 proteins as novel therapeutic targets in myeloproliferative neoplasms

Publications (1)

Publication Number Publication Date
PL4185292T3 true PL4185292T3 (pl) 2025-10-13

Family

ID=71783860

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21749566.2T PL4185292T3 (pl) 2020-07-23 2021-07-23 Białka s100 jako nowe cele terapeutyczne w przypadku nowotworów mieloproliferacyjnych

Country Status (14)

Country Link
US (1) US20230293512A1 (pl)
EP (2) EP4185292B1 (pl)
JP (1) JP7747732B2 (pl)
KR (1) KR20230043916A (pl)
CN (1) CN116782902A (pl)
AU (1) AU2021313388A1 (pl)
BR (1) BR112023000892A2 (pl)
CA (1) CA3185531A1 (pl)
ES (1) ES3037361T3 (pl)
IL (1) IL300068A (pl)
MX (1) MX2023000903A (pl)
PL (1) PL4185292T3 (pl)
WO (1) WO2022018240A1 (pl)
ZA (1) ZA202301267B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117295492A (zh) 2021-05-25 2023-12-26 活跃生物技术有限公司 多个他喹莫德粒子及其用途
JP2024524158A (ja) 2021-07-02 2024-07-05 アクティブ バイオテック エイビー タスキニモドを含有する医薬製品および前記製品の純度を評価する方法
CN114848826B (zh) * 2022-07-06 2023-03-28 北京天宇恒泰科技有限公司 用于治疗胰腺癌的组合物及用途和评价系统
AU2024306742A1 (en) * 2023-06-28 2025-12-04 Active Biotech Ab Quinoline carboxamides for use in the treatment of mpn

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
SE9801474D0 (sv) 1998-04-27 1998-04-27 Active Biotech Ab Quinoline Derivatives
SE9802549D0 (sv) 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
SE0201778D0 (sv) 2002-06-12 2002-06-12 Active Biotech Ab Process for the manufacture of quinoline derivatives
SE0400235D0 (sv) 2004-02-06 2004-02-06 Active Biotech Ab New composition containing quinoline compounds
US20100021472A1 (en) * 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
DK2590949T5 (en) 2010-07-09 2016-05-23 Active Biotech Ab METHOD OF PRODUCING quinoline-3-carboxamides
EP2537517A1 (en) 2011-06-22 2012-12-26 Active Biotech AB Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide
EA030948B1 (ru) 2014-09-23 2018-10-31 Эктив Байотек Аб Хинолинкарбоксамиды для применения в лечении множественной миеломы
EP3212239A1 (en) * 2014-10-29 2017-09-06 Westfälische Wilhelms-Universität Münster Quinoline-3-carboxamide compounds and their use in diagnosis
EA031643B1 (ru) 2014-11-19 2019-01-31 Эктив Байотек Аб Применение тасквинимода для лечения острого лимфобластного лейкоза и острого миелоидного лейкоза
US11359010B2 (en) 2015-07-13 2022-06-14 UNIVERSITé LAVAL Humanized anti-S100A9 antibody and uses thereof
US20190218299A1 (en) * 2016-05-19 2019-07-18 Momenta Pharmaceuticals, Inc. Methods for Treating Disorders Associated with Fibrosis and Systemic Sclerosis
US11554178B2 (en) * 2017-06-30 2023-01-17 City Of Hope Compositions and methods of modulating macrophage activity

Also Published As

Publication number Publication date
ZA202301267B (en) 2024-05-30
BR112023000892A2 (pt) 2023-02-07
AU2021313388A1 (en) 2023-01-19
US20230293512A1 (en) 2023-09-21
ES3037361T3 (en) 2025-10-01
EP4582448A3 (en) 2025-12-10
WO2022018240A1 (en) 2022-01-27
KR20230043916A (ko) 2023-03-31
CA3185531A1 (en) 2022-01-27
EP4185292A1 (en) 2023-05-31
IL300068A (en) 2023-03-01
JP2023535021A (ja) 2023-08-15
CN116782902A (zh) 2023-09-19
EP4185292C0 (en) 2025-05-21
JP7747732B2 (ja) 2025-10-01
EP4185292B1 (en) 2025-05-21
MX2023000903A (es) 2023-04-20
EP4582448A2 (en) 2025-07-09

Similar Documents

Publication Publication Date Title
PL4185292T3 (pl) Białka s100 jako nowe cele terapeutyczne w przypadku nowotworów mieloproliferacyjnych
CY1122165T1 (el) Αντισωματα anti-cd38
CY1119960T1 (el) Μεθοδοι για την αυξηση της αποτελεσματικοτητας της folr1 θεραπειας του καρκινου
CY1117655T1 (el) Παραγοντες οι οποιοι επαγουν αποπτωση για την αντιμετωπιση καρκινου και ανοσολογικων και αυτοανοσων νοσηματων
CY1116728T1 (el) Παραγοντες οι οποιοι επαγουν αποπτωση για την αντιμετωπιση καρκινου και ανοσολογικων και αυτοανοσων νοσηματων
CY1117423T1 (el) Παραγοντες που επηρεαζουν αποπτωση για τη θεραπεια καρκινου και ανοσων και αυτοανοσων ασθενειων
PH12015502780A1 (en) Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
MX366130B (es) Inhibidores bivalentes de las proteinas iap y métodos terapéuticos que usan los mismos.
PH12015500758A1 (en) Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
MX370814B (es) Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
SG10201808102WA (en) Bicyclic heterocycle compounds and their uses in therapy
IL231926A (en) Factors that induce apoptosis for the treatment of cancer and autoimmune and autoimmune diseases and their pharmaceutical compositions
EP3946410A4 (en) Therapeutic interferon alpha 1 proteins
WO2012170513A3 (en) He4 based therapy for malignant disease
IL291601B1 (en) Neoglycoconjugates as vaccines and therapeutic tools
PL3618848T3 (pl) Biologicznie aktywne kompleksy i ich zastosowania terapeutyczne
IL265719B1 (en) Fabp4 as a therapeutic target in skin diseases
IL290675A (en) Medical protein concentrates
BR112013012040A2 (pt) tratamento de câncer com dosagens elevadas de proteínas de fusão fdfr1 solúveis
IL285938B2 (en) Human serum albumin in formulations
SI2588480T1 (sl) Derivati 3,4-dihidropirolo(1,2-a)pirazina-2,8(1H)-dikarboksamida, njihova priprava in terapevtska uporaba
HK40092037A (zh) 作为骨髓增殖性肿瘤的新治疗靶点的s100蛋白
IL280564A (en) Selection of therapeutic proteins under simulated conditions in the living body
EP3834826A4 (en) THERAPEUTIC AGENT FOR HUMORAL IMMUNITY-RELATED DISEASES IN THE MATERNO-FETAL RELATIONSHIP
PL3277687T3 (pl) Pochodne 7-(morfolin-4-ylo)pirazolo[1,5-a]pirymidyny użyteczne do leczenia chorób immunologicznych lub zapalnych lub nowotworów