PL410572A1 - Aptamer DNA rozpoznający ludzkie białko PCNA oraz jego zastosowanie - Google Patents
Aptamer DNA rozpoznający ludzkie białko PCNA oraz jego zastosowanieInfo
- Publication number
- PL410572A1 PL410572A1 PL410572A PL41057214A PL410572A1 PL 410572 A1 PL410572 A1 PL 410572A1 PL 410572 A PL410572 A PL 410572A PL 41057214 A PL41057214 A PL 41057214A PL 410572 A1 PL410572 A1 PL 410572A1
- Authority
- PL
- Poland
- Prior art keywords
- application
- dna aptamer
- recognizing human
- pcna protein
- human pcna
- Prior art date
Links
- 108091008102 DNA aptamers Proteins 0.000 title abstract 2
- 101001072338 Homo sapiens Proliferating cell nuclear antigen Proteins 0.000 title abstract 2
- 102000044255 human PCNA Human genes 0.000 title abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Abstract
Ujawniono aptamer DNA wykazujący powinowactwo do ludzkiego białka PCNA zawierający sekwencję nukleotydową Sekw Id Nr 1 oraz jego zastosowania.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL410572A PL226916B1 (pl) | 2014-12-16 | 2014-12-16 | Aptamer DNA rozpoznajacy ludzkie białko PCNA oraz jego zastosowanie |
| EP15745259.0A EP3234142B1 (en) | 2014-12-16 | 2015-07-02 | Dna aptamer recognising human pcna protein and use thereof |
| PCT/PL2015/050026 WO2016099310A1 (en) | 2014-12-16 | 2015-07-02 | Dna aptamer recognising human pcna protein and use thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL410572A PL226916B1 (pl) | 2014-12-16 | 2014-12-16 | Aptamer DNA rozpoznajacy ludzkie białko PCNA oraz jego zastosowanie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL410572A1 true PL410572A1 (pl) | 2016-06-20 |
| PL226916B1 PL226916B1 (pl) | 2017-09-29 |
Family
ID=53773482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL410572A PL226916B1 (pl) | 2014-12-16 | 2014-12-16 | Aptamer DNA rozpoznajacy ludzkie białko PCNA oraz jego zastosowanie |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3234142B1 (pl) |
| PL (1) | PL226916B1 (pl) |
| WO (1) | WO2016099310A1 (pl) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012082069A1 (en) * | 2010-12-13 | 2012-06-21 | Agency For Science, Technology And Research | Protein aptamers based on unstructured scaffold proteins |
| PL225448B1 (pl) * | 2013-05-17 | 2017-04-28 | Univ Jagiellonski | Aptamer DNA rozpoznający metkę histydynową oraz jego zastosowanie |
-
2014
- 2014-12-16 PL PL410572A patent/PL226916B1/pl unknown
-
2015
- 2015-07-02 WO PCT/PL2015/050026 patent/WO2016099310A1/en active Application Filing
- 2015-07-02 EP EP15745259.0A patent/EP3234142B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| PL226916B1 (pl) | 2017-09-29 |
| EP3234142A1 (en) | 2017-10-25 |
| EP3234142B1 (en) | 2018-08-29 |
| WO2016099310A1 (en) | 2016-06-23 |
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