PL406737A1 - Sposób przemysłowego wytwarzania białek terapeutycznych o pożądanym profilu glikozylacji - Google Patents
Sposób przemysłowego wytwarzania białek terapeutycznych o pożądanym profilu glikozylacjiInfo
- Publication number
- PL406737A1 PL406737A1 PL406737A PL40673713A PL406737A1 PL 406737 A1 PL406737 A1 PL 406737A1 PL 406737 A PL406737 A PL 406737A PL 40673713 A PL40673713 A PL 40673713A PL 406737 A1 PL406737 A1 PL 406737A1
- Authority
- PL
- Poland
- Prior art keywords
- therapeutic proteins
- glycosylation
- industrial production
- desired profile
- transglycosylation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Przemysłowy sposób wytwarzania białek terapeutycznych o stałym, pożądanym profilu glikozylacji, polega na zastosowaniu w formacie kolumnowym reakcji deglikozylacji, a następnie transglikozylacji białka terapeutycznego w obecności aktywnej pochodnej glikanu.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL406737A PL406737A1 (pl) | 2013-12-31 | 2013-12-31 | Sposób przemysłowego wytwarzania białek terapeutycznych o pożądanym profilu glikozylacji |
PCT/PL2014/000152 WO2015102501A1 (en) | 2013-12-31 | 2014-12-22 | Method for industrial scale production of therapeutically active proteins of desired glycosylation pattern |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL406737A PL406737A1 (pl) | 2013-12-31 | 2013-12-31 | Sposób przemysłowego wytwarzania białek terapeutycznych o pożądanym profilu glikozylacji |
Publications (1)
Publication Number | Publication Date |
---|---|
PL406737A1 true PL406737A1 (pl) | 2015-07-06 |
Family
ID=53492772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL406737A PL406737A1 (pl) | 2013-12-31 | 2013-12-31 | Sposób przemysłowego wytwarzania białek terapeutycznych o pożądanym profilu glikozylacji |
Country Status (2)
Country | Link |
---|---|
PL (1) | PL406737A1 (pl) |
WO (1) | WO2015102501A1 (pl) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3452605A1 (en) | 2016-05-03 | 2019-03-13 | Vib Vzw | Means and methods for generating complex glycans derived from fungal engineered hosts |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10851174B2 (en) * | 2011-03-03 | 2020-12-01 | University Of Maryland, Baltimore | Core fucosylated glycopeptides and glycoproteins: chemoenzymatic synthesis and uses thereof |
EP2812442B9 (en) * | 2012-02-10 | 2023-02-15 | University of Maryland, Baltimore | Chemoenzymatic glycoengineering of antibodies and fc fragments thereof |
-
2013
- 2013-12-31 PL PL406737A patent/PL406737A1/pl unknown
-
2014
- 2014-12-22 WO PCT/PL2014/000152 patent/WO2015102501A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2015102501A1 (en) | 2015-07-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112017016338A2 (pt) | produção de glicosídeos de esteviol em hospedeiros recombinantes | |
MX2020001823A (es) | Fabricacion continua integrada de principios activos proteinicos terapeuticos. | |
BR112015029933A2 (pt) | método de produção de tagatose | |
PL2994229T3 (pl) | Sposób wytwarzania 1,3-butadienu | |
MX368142B (es) | Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab. | |
EP3533541A4 (en) | METHOD FOR PRODUCING SILVER NANO WIRE | |
EP3385305A4 (en) | PROCESS FOR PRODUCING A PROTEIN SOLUTION | |
MY181068A (en) | Recombinant microorganism for improved production of fine chemicals | |
EP3269755A4 (en) | Process for producing low-concentration gel using gel-precursor clusters, and gel obtained by said production process | |
MX2016007297A (es) | Proceso para purificar 2,5-diclorofenol. | |
SG11201508384TA (en) | Process of producing 1,4-butanediol | |
DK3527667T3 (da) | Gærpromotorer til proteinekspression | |
EP3087851A4 (en) | Method for producing tobacco material, and tobacco material produced by said production method | |
BR112016013371A2 (pt) | melhorias em proteína de fusão pesticida | |
EP2990476A4 (en) | Method for producing protein | |
MY168066A (en) | Cigarette Production Method, Cigarette, and Double Cigarette | |
CL2015002080A1 (es) | Métodos de control selectivo de malezas | |
EA201791423A1 (ru) | Способ получения белка | |
PL406737A1 (pl) | Sposób przemysłowego wytwarzania białek terapeutycznych o pożądanym profilu glikozylacji | |
EA201692246A1 (ru) | Способ получения 2,6-диметилбензохинона | |
MX2015010006A (es) | Purificacion de proteinas mejorada a traves de una etapa de desglicosilacion. | |
EP3047857A4 (en) | Treatment for hemorrhagic diseases by anti-protein-c antibody | |
MX2015009565A (es) | Proceso para elaborar derivados de magnolol. | |
EP3041814B8 (en) | Process for the production of dichlorohydrins | |
EA201500764A1 (ru) | Способ получения 2-алкил-3-бутин-2-олов |