PL3820439T3 - Mukoadhezyjny układ dyspersji nanocząsteczek i sposób jego wytwarzania - Google Patents

Mukoadhezyjny układ dyspersji nanocząsteczek i sposób jego wytwarzania

Info

Publication number
PL3820439T3
PL3820439T3 PL18786389T PL18786389T PL3820439T3 PL 3820439 T3 PL3820439 T3 PL 3820439T3 PL 18786389 T PL18786389 T PL 18786389T PL 18786389 T PL18786389 T PL 18786389T PL 3820439 T3 PL3820439 T3 PL 3820439T3
Authority
PL
Poland
Prior art keywords
production
same
nanoparticle system
dispersion nanoparticle
mucoadhesive dispersion
Prior art date
Application number
PL18786389T
Other languages
English (en)
Inventor
Christo Tzachev Tzachev
Original Assignee
Lead Biotherapeutics Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lead Biotherapeutics Ltd. filed Critical Lead Biotherapeutics Ltd.
Publication of PL3820439T3 publication Critical patent/PL3820439T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
PL18786389T 2018-09-11 2018-09-11 Mukoadhezyjny układ dyspersji nanocząsteczek i sposób jego wytwarzania PL3820439T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2018/001073 WO2020053609A1 (en) 2018-09-11 2018-09-11 Mucoadhesive dispersion nanoparticle system and method for production the same
EP18786389.9A EP3820439B1 (en) 2018-09-11 2018-09-11 Mucoadhesive dispersion nanoparticle system and method for production the same

Publications (1)

Publication Number Publication Date
PL3820439T3 true PL3820439T3 (pl) 2022-04-04

Family

ID=63857975

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18786389T PL3820439T3 (pl) 2018-09-11 2018-09-11 Mukoadhezyjny układ dyspersji nanocząsteczek i sposób jego wytwarzania

Country Status (14)

Country Link
US (1) US12036329B2 (pl)
EP (1) EP3820439B1 (pl)
JP (1) JP7164700B2 (pl)
CA (1) CA3110773C (pl)
DK (1) DK3820439T3 (pl)
ES (1) ES2901469T3 (pl)
HR (1) HRP20211996T1 (pl)
HU (1) HUE056959T2 (pl)
IL (1) IL280371B (pl)
LT (1) LT3820439T (pl)
MX (1) MX2021001397A (pl)
PL (1) PL3820439T3 (pl)
SI (1) SI3820439T1 (pl)
WO (1) WO2020053609A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3085694A1 (en) * 2017-12-12 2019-06-20 Lead Biotherapeutics Ltd. Solid lipid nanoparticle for intracellular release of active substances and method for production the same
CN120788994B (zh) * 2025-09-12 2025-11-14 广东海洋大学 一种具有增溶和促吸收作用的纳米复合物及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603131A (en) 1982-04-26 1986-07-29 Bernstein Joel E Method and composition for treating and preventing irritation of the mucous membranes of the nose
US5976573A (en) 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
EP1051155B1 (en) 1998-01-30 2002-06-26 Novartis Consumer Health S.A. Nasal solutions
US6319513B1 (en) 1998-08-24 2001-11-20 The Procter & Gamble Company Oral liquid mucoadhesive compounds
GB2423711B (en) 2005-10-24 2007-02-14 Fortune Apex Dev Ltd Method for preparing a pharmaceutical composition with enhanced mucoadhesion
ES2284398B2 (es) 2006-04-27 2008-12-16 Universidad Complutense De Madrid Formulacion de vesiculas liposomales en soluciones acuosas con caracteristicas de pelicula lagrimal.
US8242165B2 (en) 2006-10-26 2012-08-14 Creighton University Mucoadhesive nanoparticles for cancer treatment
EP2123261A1 (en) 2008-05-20 2009-11-25 Stallergenes S.A. Mucoadhesive particulate formulation for inducing antigen-specific immune tolerance
EP2601201B1 (en) * 2010-08-04 2014-09-24 Meril Life Sciences Pvt. Ltd. Process for preparation of novel 42-0-(heteroalkoxyalkyl) rapamycin compounds with anti-proliferative properties"
KR20140031227A (ko) * 2011-03-24 2014-03-12 레오 파마 에이/에스 지질 나노입자들 및 코르티코스테로이드 또는 비타민 d 유도체를 포함하는 조성물
CN104507458B (zh) 2012-06-20 2018-05-22 滑铁卢大学 粘膜粘合剂纳米颗粒递送系统
WO2014203210A1 (en) * 2013-06-20 2014-12-24 Glenmark Pharmaceuticals S.A. Nanoparticulate formulation comprising a trpa1 antagonist
CN103784421B (zh) * 2014-02-27 2016-04-27 哈尔滨医科大学 载姜黄素和胡椒碱的固体脂质纳米粒及其制备方法
AU2015277272A1 (en) 2014-06-16 2017-01-12 Loewi LLC Methods of anesthetizing nerve tissue in the trigeminal nerve pathway and medical uses thereof
JP2016034918A (ja) * 2014-08-01 2016-03-17 静岡県公立大学法人 難水溶性抗酸化物質送達用組成物
AU2016343840A1 (en) 2015-10-30 2018-06-07 The Johns Hopkins University Mucus penetrating particles with high molecular weight and dense coatings
BE1024228B1 (fr) 2015-12-08 2017-12-21 Glaxosmithkline Biologicals Sa Nouvelles formulations d'adjuvants

Also Published As

Publication number Publication date
SI3820439T1 (sl) 2022-02-28
IL280371B (en) 2021-05-31
WO2020053609A1 (en) 2020-03-19
ES2901469T3 (es) 2022-03-22
HUE056959T2 (hu) 2022-04-28
DK3820439T3 (da) 2021-12-20
CA3110773C (en) 2023-02-28
EP3820439B1 (en) 2021-09-29
US12036329B2 (en) 2024-07-16
LT3820439T (lt) 2022-01-10
IL280371A (en) 2021-03-01
CA3110773A1 (en) 2020-03-19
EP3820439A1 (en) 2021-05-19
HRP20211996T1 (hr) 2022-04-01
BR112021001674A2 (pt) 2021-05-04
US20210353553A1 (en) 2021-11-18
JP7164700B2 (ja) 2022-11-01
MX2021001397A (es) 2021-04-12
JP2022511223A (ja) 2022-01-31

Similar Documents

Publication Publication Date Title
SG11202100317YA (en) System and method for the production of biomolecules
EP3584709A4 (en) ONLINE MAINTENANCE SYSTEM AND PROCEDURE FOR PRODUCTION DEVICE
EP3362366A4 (en) BUNDLED PRODUCT AND SYSTEM AND METHOD FOR THE PRODUCTION THEREOF
EP3585511A4 (en) METAL MOLYBDATE AND METHOD FOR MANUFACTURING THEREOF
EP3732027C0 (en) SUB-MICRON ADDITIVE MANUFACTURING SYSTEM AND PROCESS
EP3428867A4 (en) PAYMENT METHOD AND SYSTEM
PL3402709T3 (pl) Pojazd konserwacyjny oraz sposób
EP3776285A4 (en) METHOD AND SYSTEM FOR CHARACTERIZING MICRO-ORGANISM-RELATED CONDITIONS
GB201820935D0 (en) Manufacturing system and method
EP3424680A4 (en) APPARATUS AND METHOD FOR MANUFACTURING STRINGS
EP3583955A4 (en) EXOSOME-BASED NANOPARTICLE COMPOSITE AND METHOD FOR MANUFACTURING THEREOF
ZA201805714B (en) System and method for producing 3.5-valence high-purity vanadium electrolyte
EP3412694A4 (en) Aqueous dispersion, production method for same, and image formation method
EP3252780A4 (en) Silver-coated particles and method for producing same
SG10201905946YA (en) Systems and Methods for Fabricating Nanoparticles
EP3462769A4 (en) METHOD, APPARATUS AND SYSTEM FOR CHARGE MIGRATION
EP3625599B8 (de) Photonisches bauelement und verfahren zu dessen herstellung
HUP1600584A2 (hu) Termelési folyamat integráló rendszer és eljárás
IL280371B (en) A nano-particle system for mucosal dispersion-adhesion and a method for its production
DK3211175T3 (en) Hoisting system and method for operating the same
EP3524439A4 (en) PICTURE PRODUCTION METHOD AND PICTURE GENERATION SYSTEM
GB201618357D0 (en) Particle filter and method for the production thereof
PL3291999T3 (pl) Cecha bezpieczeństwa i sposób jej wytwarzania
ZA201902098B (en) Method and system for producing benzene
EP3513331A4 (en) SYSTEM AND METHOD FOR FORMATIVE FEEDBACK