PL381265A1 - Sposób wytwarzania dideoksyinozyny z użyciem enzymu deaminazy adenozyny - Google Patents

Sposób wytwarzania dideoksyinozyny z użyciem enzymu deaminazy adenozyny

Info

Publication number
PL381265A1
PL381265A1 PL381265A PL38126504A PL381265A1 PL 381265 A1 PL381265 A1 PL 381265A1 PL 381265 A PL381265 A PL 381265A PL 38126504 A PL38126504 A PL 38126504A PL 381265 A1 PL381265 A1 PL 381265A1
Authority
PL
Poland
Prior art keywords
dideoxyinosine
aid
production
adenosine deaminase
deaminase enzyme
Prior art date
Application number
PL381265A
Other languages
English (en)
Inventor
Paul M. Skonezny
Michael Politino
Suo W. Liu
Alfred W. Boyle
Jason G. Chen
Gregory L. Stein
Thomas Franceschini
Wendy L. Anderson
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of PL381265A1 publication Critical patent/PL381265A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PL381265A 2003-03-04 2004-02-27 Sposób wytwarzania dideoksyinozyny z użyciem enzymu deaminazy adenozyny PL381265A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45184203P 2003-03-04 2003-03-04

Publications (1)

Publication Number Publication Date
PL381265A1 true PL381265A1 (pl) 2007-05-14

Family

ID=32962647

Family Applications (1)

Application Number Title Priority Date Filing Date
PL381265A PL381265A1 (pl) 2003-03-04 2004-02-27 Sposób wytwarzania dideoksyinozyny z użyciem enzymu deaminazy adenozyny

Country Status (12)

Country Link
US (1) US20040175804A1 (pl)
EP (1) EP1618204A4 (pl)
JP (1) JP2007525163A (pl)
KR (1) KR20050109956A (pl)
CN (1) CN1954080A (pl)
AU (1) AU2004217521A1 (pl)
BR (1) BRPI0407959A (pl)
CA (1) CA2517674A1 (pl)
MX (1) MXPA05009261A (pl)
PL (1) PL381265A1 (pl)
TW (1) TW200506062A (pl)
WO (1) WO2004078993A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008131163A1 (en) * 2007-04-20 2008-10-30 Enzon Pharmaceuticals, Inc. Enzymatic anticancer therapy
US8624217B2 (en) 2010-06-25 2014-01-07 International Business Machines Corporation Planar phase-change memory cell with parallel electrical paths
US8575008B2 (en) 2010-08-31 2013-11-05 International Business Machines Corporation Post-fabrication self-aligned initialization of integrated devices
CN103451255B (zh) * 2013-03-28 2016-03-16 南京工业大学 次黄嘌呤核苷酸的生产方法
CN107974476B (zh) * 2018-01-10 2020-12-29 中国科学院沈阳应用生态研究所 一种虫草素转化为3’-脱氧肌苷的生物转化方法
CN111921505B (zh) * 2020-08-06 2022-08-09 同济大学 邻二醇功能化大孔通孔材料及其制备方法和硼酸吸附应用
WO2023034742A1 (en) * 2021-08-30 2023-03-09 The Board Of Trustees Of The Leland Stanford Junior University T cells with cell-surface expression of adenosine deaminase and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835104A (en) * 1987-06-16 1989-05-30 Ajinomoto Co., Inc., Patent & Licensing Department Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
US5011774A (en) * 1987-07-17 1991-04-30 Bristol-Myers Squibb Co. Dideoxyinosine by enzymatic deamination of dideoxyadenosine
JPH0757198B2 (ja) * 1987-10-07 1995-06-21 味の素株式会社 ジデオキシイノシンの製造方法
US6010853A (en) * 1997-05-29 2000-01-04 Dana-Farber Cancer Institute Siva genes, novel genes involved in CD27-mediated apoptosis
US6068991A (en) * 1997-12-16 2000-05-30 Bristol-Myers Squibb Company High expression Escherichia coli expression vector
WO2000005217A1 (en) * 1998-07-23 2000-02-03 Fujisawa Pharmaceutical Co., Ltd. Imidazole compounds and their use as adenosine deaminase inhibitors
WO2002014483A2 (en) * 2000-08-15 2002-02-21 Zymogenetics Inc Human adenosine deaminase

Also Published As

Publication number Publication date
AU2004217521A1 (en) 2004-09-16
TW200506062A (en) 2005-02-16
US20040175804A1 (en) 2004-09-09
JP2007525163A (ja) 2007-09-06
KR20050109956A (ko) 2005-11-22
EP1618204A4 (en) 2007-05-30
WO2004078993A3 (en) 2006-10-05
MXPA05009261A (es) 2005-10-19
CN1954080A (zh) 2007-04-25
WO2004078993A2 (en) 2004-09-16
CA2517674A1 (en) 2004-09-16
EP1618204A2 (en) 2006-01-25
BRPI0407959A (pt) 2006-03-07

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