PL3765475T3 - Podstawione rybonukleozydy pirydopirolopirymidynowe do zastosowań terapeutycznych - Google Patents

Podstawione rybonukleozydy pirydopirolopirymidynowe do zastosowań terapeutycznych

Info

Publication number
PL3765475T3
PL3765475T3 PL19710587T PL19710587T PL3765475T3 PL 3765475 T3 PL3765475 T3 PL 3765475T3 PL 19710587 T PL19710587 T PL 19710587T PL 19710587 T PL19710587 T PL 19710587T PL 3765475 T3 PL3765475 T3 PL 3765475T3
Authority
PL
Poland
Prior art keywords
therapeutic uses
ribonucleosides
substituted
substituted pyridopyrrolopyrimidine
pyridopyrrolopyrimidine ribonucleosides
Prior art date
Application number
PL19710587T
Other languages
English (en)
Inventor
Lucia VESELOVSKA
Michal Hocek
Marian Hajduch
Petr DZUBAK
Original Assignee
Ustav Organicke Chemie A Biochemie Av Cr, V.V.I.
Univerzita Palackeho V Olomouci
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ustav Organicke Chemie A Biochemie Av Cr, V.V.I., Univerzita Palackeho V Olomouci filed Critical Ustav Organicke Chemie A Biochemie Av Cr, V.V.I.
Publication of PL3765475T3 publication Critical patent/PL3765475T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL19710587T 2018-03-12 2019-03-04 Podstawione rybonukleozydy pirydopirolopirymidynowe do zastosowań terapeutycznych PL3765475T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ2018-121A CZ308104B6 (cs) 2018-03-12 2018-03-12 Pyridinopyrrolopyrimidinové ribonukleosidy pro terapeutické použití
PCT/CZ2019/050008 WO2019174657A1 (en) 2018-03-12 2019-03-04 Substituted pyridopyrrolopyrimidine ribonucleosides for therapeutic uses
EP19710587.7A EP3765475B1 (en) 2018-03-12 2019-03-04 Substituted pyridopyrrolopyrimidine ribonucleosides for therapeutic uses

Publications (1)

Publication Number Publication Date
PL3765475T3 true PL3765475T3 (pl) 2022-01-31

Family

ID=65763222

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19710587T PL3765475T3 (pl) 2018-03-12 2019-03-04 Podstawione rybonukleozydy pirydopirolopirymidynowe do zastosowań terapeutycznych

Country Status (9)

Country Link
US (1) US11299510B2 (pl)
EP (1) EP3765475B1 (pl)
JP (1) JP6973761B2 (pl)
AU (1) AU2019235042B2 (pl)
CA (1) CA3090343C (pl)
CZ (1) CZ308104B6 (pl)
ES (1) ES2898344T3 (pl)
PL (1) PL3765475T3 (pl)
WO (1) WO2019174657A1 (pl)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004035580A1 (en) * 2002-10-21 2004-04-29 Aprea Ab Reactivation of wild type p53 in human tumour cells by a low molecular weight compound
WO2005025515A2 (en) * 2003-09-12 2005-03-24 California Institute Of Technology Proteasome pathway inhibitors and related methods
HUE030767T2 (en) 2008-01-18 2017-05-29 Inst Of Organic Chemistry And Biochemistry Of The Acad Of Sciences Of The Czech Republic New, cytostatic 7-deazapurine nucleosides
EP2421879B1 (en) 2009-04-22 2013-09-04 Institute Of Organic Chemistry And Biochemistry As CR, V.V.I. Novel 7-deazapurine nucleosides for therapeutic uses
EP3478701B1 (en) * 2016-06-29 2022-08-10 Ustav organicke chemie a biochemie AV CR, v.v.i. Substituted thienopyrrolopyrimidine ribonucleosides for therapeutic use
CN107441501B (zh) 2016-07-01 2020-11-10 四川大学 抗菌肽修饰的载药脂质体及其制备方法和用途
CZ307334B6 (cs) * 2016-08-02 2018-06-13 Ăšstav organickĂ© chemie a biochemie AV ÄŚR, v.v.i. Substituované heteropentadieno-pyrrolopyrimidinové ribonukleosidy pro terapeutické použití

Also Published As

Publication number Publication date
CZ2018121A3 (cs) 2019-09-25
AU2019235042A1 (en) 2020-09-10
CA3090343C (en) 2022-10-04
JP6973761B2 (ja) 2021-12-01
JP2021516687A (ja) 2021-07-08
ES2898344T3 (es) 2022-03-07
CA3090343A1 (en) 2019-09-19
US11299510B2 (en) 2022-04-12
EP3765475B1 (en) 2021-09-15
AU2019235042B2 (en) 2021-03-04
US20210002321A1 (en) 2021-01-07
CZ308104B6 (cs) 2020-01-08
WO2019174657A1 (en) 2019-09-19
EP3765475A1 (en) 2021-01-20

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