PL375350A1 - Pochodne indolu i ich zastosowanie jako ligandów 5-HT - Google Patents

Pochodne indolu i ich zastosowanie jako ligandów 5-HT

Info

Publication number
PL375350A1
PL375350A1 PL03375350A PL37535003A PL375350A1 PL 375350 A1 PL375350 A1 PL 375350A1 PL 03375350 A PL03375350 A PL 03375350A PL 37535003 A PL37535003 A PL 37535003A PL 375350 A1 PL375350 A1 PL 375350A1
Authority
PL
Poland
Prior art keywords
ligands
indol derivatives
indol
derivatives
formula
Prior art date
Application number
PL03375350A
Other languages
English (en)
Inventor
Günter Hölzemann
Helene Crassier
Henning Böttcher
Timo Heinrich
Kai Schiemann
Joachim Leibrock
Amsterdam Christoph Van
Gerd Bartoszyk
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL375350A1 publication Critical patent/PL375350A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL03375350A 2002-12-10 2003-11-17 Pochodne indolu i ich zastosowanie jako ligandów 5-HT PL375350A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02027483 2002-12-10

Publications (1)

Publication Number Publication Date
PL375350A1 true PL375350A1 (pl) 2005-11-28

Family

ID=32479712

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03375350A PL375350A1 (pl) 2002-12-10 2003-11-17 Pochodne indolu i ich zastosowanie jako ligandów 5-HT

Country Status (15)

Country Link
US (1) US7482465B2 (pl)
EP (1) EP1569930B1 (pl)
JP (1) JP4563817B2 (pl)
KR (1) KR20050085472A (pl)
CN (1) CN1723209A (pl)
AT (1) ATE350381T1 (pl)
AU (1) AU2003288077B2 (pl)
BR (1) BR0317126A (pl)
CA (1) CA2509225C (pl)
DE (1) DE60311000T2 (pl)
ES (1) ES2279976T3 (pl)
MX (1) MXPA05006076A (pl)
PL (1) PL375350A1 (pl)
WO (1) WO2004052886A1 (pl)
ZA (1) ZA200505491B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7371769B2 (en) 2004-12-07 2008-05-13 Solvay Pharmaceuticals B.V. Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites
US20060122247A1 (en) 2004-12-08 2006-06-08 Solvay Pharmaceuticals B.V. Aryloxyethylamine and phenylpiperazine derivatives with a combination of partial dopamine-D2 receptor agonism and serotonin reuptake inhibition
AU2005313390A1 (en) * 2004-12-08 2006-06-15 Solvay Pharmaceuticals B.V. Aryloxyethylamine derivatives with a combination of partial dopamine-D2 receptor agonism and serotonin reuptake inhibition
EP2771341A4 (en) * 2011-10-28 2015-09-23 Univ Texas NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8830312D0 (en) 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
US5607960A (en) * 1993-04-22 1997-03-04 Pfizer Inc. Indole derivatives as 5-HT1-like agonists for use in migraine
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
GB9903784D0 (en) * 1999-02-18 1999-04-14 Lilly Co Eli Pharmaceutical compounds

Also Published As

Publication number Publication date
MXPA05006076A (es) 2005-08-16
ATE350381T1 (de) 2007-01-15
CN1723209A (zh) 2006-01-18
ZA200505491B (en) 2006-05-31
DE60311000T2 (de) 2007-10-04
DE60311000D1 (de) 2007-02-15
AU2003288077A1 (en) 2004-06-30
US7482465B2 (en) 2009-01-27
WO2004052886A1 (en) 2004-06-24
AU2003288077B2 (en) 2010-05-27
JP2006510641A (ja) 2006-03-30
JP4563817B2 (ja) 2010-10-13
ES2279976T3 (es) 2007-09-01
EP1569930B1 (en) 2007-01-03
CA2509225A1 (en) 2004-06-24
US20060116405A1 (en) 2006-06-01
CA2509225C (en) 2011-09-20
EP1569930A1 (en) 2005-09-07
BR0317126A (pt) 2005-10-25
KR20050085472A (ko) 2005-08-29

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)