PL374799A1 - Nowa sól i odmiany polimorficzne hemifumaranu desloratadyny - Google Patents

Nowa sól i odmiany polimorficzne hemifumaranu desloratadyny

Info

Publication number
PL374799A1
PL374799A1 PL03374799A PL37479903A PL374799A1 PL 374799 A1 PL374799 A1 PL 374799A1 PL 03374799 A PL03374799 A PL 03374799A PL 37479903 A PL37479903 A PL 37479903A PL 374799 A1 PL374799 A1 PL 374799A1
Authority
PL
Poland
Prior art keywords
polymorphs
novel salt
hemifumarate
desloratadine
desloratadine hemifumarate
Prior art date
Application number
PL03374799A
Other languages
English (en)
Inventor
Anup Kumar Ray
Hiren Kumar V. Patel
Mahendra R. Patel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of PL374799A1 publication Critical patent/PL374799A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL03374799A 2002-08-05 2003-07-17 Nowa sól i odmiany polimorficzne hemifumaranu desloratadyny PL374799A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40115302P 2002-08-05 2002-08-05

Publications (1)

Publication Number Publication Date
PL374799A1 true PL374799A1 (pl) 2005-10-31

Family

ID=31495932

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03374799A PL374799A1 (pl) 2002-08-05 2003-07-17 Nowa sól i odmiany polimorficzne hemifumaranu desloratadyny

Country Status (17)

Country Link
US (1) US6962924B2 (pl)
EP (1) EP1539161A1 (pl)
JP (1) JP2005539010A (pl)
KR (1) KR20050069976A (pl)
CN (1) CN1674901A (pl)
AU (1) AU2003251974C1 (pl)
BR (1) BR0313231A (pl)
CA (1) CA2494288A1 (pl)
EC (1) ECSP055580A (pl)
HR (1) HRP20050110A2 (pl)
IL (1) IL166289A0 (pl)
MX (1) MXPA05001470A (pl)
NO (1) NO20051166L (pl)
PL (1) PL374799A1 (pl)
RU (1) RU2005106205A (pl)
WO (1) WO2004012738A1 (pl)
ZA (1) ZA200500372B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2232331T1 (es) * 2003-03-12 2005-06-01 Biogal Gyogyszergyar Rt. Procedimientos para la preparacion de formas polimorficas de desloratadina.
RS20070008A (en) * 2004-07-07 2008-11-28 Egis Gyogyszergyar Rt., New pseudopolymorph of desloratidine formed with carbon dioxide
CA2541045A1 (en) * 2006-03-24 2007-09-24 Pharmascience Inc. A descarbonylethoxyloratadine containing pharmaceutical composition
US20090082385A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched desloratidine
CN110638750B (zh) * 2019-10-28 2021-08-27 深圳市贝美药业有限公司 一种地氯雷他定药物的制备方法及其制剂
CN113081958B (zh) * 2021-05-01 2022-05-03 安徽新世纪药业有限公司 一种地氯雷他定口服溶液及其制备方法
CN115785065A (zh) * 2022-12-02 2023-03-14 山东达因海洋生物制药股份有限公司 一种地氯雷他定共晶及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU194864B (en) * 1984-02-15 1988-03-28 Schering Corp Process for production of 8-chlor-6,11-dihydro-11-(4-piperidilidene)-5h-benzo (5,6)-cyclo-hepta (1,2-b) pyridine and its salts
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US4954503A (en) * 1989-09-11 1990-09-04 Hoechst-Roussel Pharmaceuticals, Inc. 3-(1-substituted-4-piperazinyl)-1H-indazoles
AU1945495A (en) * 1994-03-16 1995-10-03 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
US6506767B1 (en) * 1997-07-02 2003-01-14 Schering Corporation 8-chloro-6,11-dihydro-11-(4-piperidylidine)-5H-benzo[5,6]cyclohepta[1-2-b] pyridine
UA62976C2 (en) * 1997-07-02 2004-01-15 Schering Corp Polymorphs of 8-chloro-6,11-dihydro-11-(4-piperidylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridine
US6335347B1 (en) * 1997-10-10 2002-01-01 Schering Corporation Ethyl 4-(8-chloro-5,6-dihydro-11 H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidene carboxylate polymorph
WO1999019322A1 (en) * 1997-10-10 1999-04-22 Schering Corporation ETHYL 4-(8-CHLORO-5, 6-DIHYDRO-11H- BENZO[5,6]CYCLOHEPTA [1,2-b]PYRIDIN -11-YLIDENE)-1- PIPERIDENE CARBOXYLATE POLYMORPH
US6100274A (en) * 1999-07-07 2000-08-08 Schering Corporation 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
HU226998B1 (en) * 2000-11-23 2010-04-28 Richter Gedeon Nyrt Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
BR0313231A (pt) 2007-07-24
US6962924B2 (en) 2005-11-08
CA2494288A1 (en) 2004-02-12
MXPA05001470A (es) 2005-09-30
KR20050069976A (ko) 2005-07-05
JP2005539010A (ja) 2005-12-22
HRP20050110A2 (en) 2006-02-28
AU2003251974C1 (en) 2006-09-14
ZA200500372B (en) 2006-07-26
AU2003251974B2 (en) 2006-04-27
EP1539161A1 (en) 2005-06-15
IL166289A0 (en) 2006-01-15
US20040058949A1 (en) 2004-03-25
NO20051166L (no) 2005-03-04
AU2003251974A1 (en) 2004-02-23
WO2004012738A1 (en) 2004-02-12
CN1674901A (zh) 2005-09-28
RU2005106205A (ru) 2005-12-10
ECSP055580A (es) 2005-04-18

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)