PL3720433T3 - Tetratiomolibdenian bis-choliny do leczenia choroby wilsona - Google Patents

Tetratiomolibdenian bis-choliny do leczenia choroby wilsona

Info

Publication number
PL3720433T3
PL3720433T3 PL18815624.4T PL18815624T PL3720433T3 PL 3720433 T3 PL3720433 T3 PL 3720433T3 PL 18815624 T PL18815624 T PL 18815624T PL 3720433 T3 PL3720433 T3 PL 3720433T3
Authority
PL
Poland
Prior art keywords
bis
wilson disease
choline tetrathiomolybdate
treating wilson
treating
Prior art date
Application number
PL18815624.4T
Other languages
English (en)
Inventor
Aftab ALA
Carl BJARTMAR
Karl-Heinz Weiss
Michael SCHILSKY
Frederick ASKARI
Anna CZLONKOWSKA
Peter Ferenci
Peter HEDERA
Original Assignee
Alexion Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexion Pharmaceuticals, Inc. filed Critical Alexion Pharmaceuticals, Inc.
Publication of PL3720433T3 publication Critical patent/PL3720433T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL18815624.4T 2017-12-04 2018-12-04 Tetratiomolibdenian bis-choliny do leczenia choroby wilsona PL3720433T3 (pl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762594184P 2017-12-04 2017-12-04
US201862646553P 2018-03-22 2018-03-22
US201862655568P 2018-04-10 2018-04-10
US201862669095P 2018-05-09 2018-05-09
US201862741313P 2018-10-04 2018-10-04
US201862750595P 2018-10-25 2018-10-25
PCT/EP2018/083551 WO2019110619A1 (en) 2017-12-04 2018-12-04 Bis-choline tetrathiomolybdate for treating wilson disease

Publications (1)

Publication Number Publication Date
PL3720433T3 true PL3720433T3 (pl) 2022-07-18

Family

ID=64661349

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18815624.4T PL3720433T3 (pl) 2017-12-04 2018-12-04 Tetratiomolibdenian bis-choliny do leczenia choroby wilsona
PL21215264.9T PL4029498T3 (pl) 2017-12-04 2018-12-04 Tetrathiomolibdenian bis-choliny do leczenia choroby wilsona

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL21215264.9T PL4029498T3 (pl) 2017-12-04 2018-12-04 Tetrathiomolibdenian bis-choliny do leczenia choroby wilsona

Country Status (16)

Country Link
US (3) US11510944B2 (pl)
EP (3) EP4029498B1 (pl)
JP (3) JP7852200B2 (pl)
KR (1) KR102803161B1 (pl)
AU (1) AU2018379255B2 (pl)
BR (1) BR112020011055A2 (pl)
DK (2) DK4029498T3 (pl)
ES (2) ES3026756T3 (pl)
FI (1) FI4029498T3 (pl)
HU (2) HUE071155T2 (pl)
IL (1) IL275115B2 (pl)
MX (1) MX2020006284A (pl)
PL (2) PL3720433T3 (pl)
PT (2) PT3720433T (pl)
SI (2) SI3720433T1 (pl)
WO (1) WO2019110619A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11419832B2 (en) * 2017-12-04 2022-08-23 Alexion Pharmaceuticals, Inc. Bis-choline tetrathiomolybdate for treating Wilson Disease
KR102803161B1 (ko) * 2017-12-04 2025-05-07 알렉시온 파마 인터내셔널 오퍼레이션즈 리미티드 윌슨병을 치료하기 위한 비스-콜린 테트라티오몰리브데이트
WO2019154876A1 (en) 2018-02-06 2019-08-15 Wilson Therapeutics Ab Crystalline particles of bis-choline tetrathiomolybdate
US20220387370A1 (en) 2019-11-21 2022-12-08 Alexion Pharmaceuticals, Inc. Methods of reducing neurological damage in wilson disease patients
JP2023542497A (ja) * 2020-09-11 2023-10-10 アレクシオン ファーマシューティカルズ, インコーポレイテッド 抗セルロプラスミン抗体及びその使用
CA3172751A1 (en) 2020-11-13 2022-05-19 Alexion Pharmaceuticals, Inc. Methods of treating copper metabolism-associated diseases or disorders
WO2022165339A1 (en) * 2021-01-31 2022-08-04 Alexion Pharmaceuticals, Inc. Novel formulation for treating copper metabolism-associated diseases or disorders
JP2024532131A (ja) * 2021-08-17 2024-09-05 アレクシオン ファーマシューティカルズ, インコーポレイテッド 銅代謝関連疾患又は障害を治療する方法
WO2023038909A1 (en) * 2021-09-07 2023-03-16 Alexion Pharmaceuticals, Inc. Methods of treating copper metabolism-associated diseases or disorders
CN121358471A (zh) 2023-01-30 2026-01-16 阿雷克森制药公司 用于治疗铜代谢相关疾病或病症(威尔逊病)的四硫代钼酸

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2493341A1 (en) 2002-07-23 2004-01-29 The Regents Of The University Of Michigan Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies
US7189865B2 (en) 2002-07-23 2007-03-13 Attenuon, Llc Thiomolybdate analogues and uses thereof
WO2007084818A2 (en) * 2006-01-10 2007-07-26 Pipex, Inc. Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
US9623021B2 (en) 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
US11419832B2 (en) * 2017-12-04 2022-08-23 Alexion Pharmaceuticals, Inc. Bis-choline tetrathiomolybdate for treating Wilson Disease
KR102803161B1 (ko) 2017-12-04 2025-05-07 알렉시온 파마 인터내셔널 오퍼레이션즈 리미티드 윌슨병을 치료하기 위한 비스-콜린 테트라티오몰리브데이트
WO2019154876A1 (en) 2018-02-06 2019-08-15 Wilson Therapeutics Ab Crystalline particles of bis-choline tetrathiomolybdate

Also Published As

Publication number Publication date
PT3720433T (pt) 2022-05-03
US12233088B2 (en) 2025-02-25
JP7852200B2 (ja) 2026-04-28
EP4523745A2 (en) 2025-03-19
AU2018379255A1 (en) 2020-06-25
PL4029498T3 (pl) 2025-06-02
US20230070534A1 (en) 2023-03-09
US20210177894A1 (en) 2021-06-17
ES2912306T3 (es) 2022-05-25
IL275115B2 (en) 2025-10-01
BR112020011055A2 (pt) 2020-11-17
US11510944B2 (en) 2022-11-29
HUE058921T2 (hu) 2022-09-28
KR20200096798A (ko) 2020-08-13
EP4029498A1 (en) 2022-07-20
JP2023075247A (ja) 2023-05-30
CA3084100A1 (en) 2019-06-13
KR102803161B1 (ko) 2025-05-07
ES3026756T3 (en) 2025-06-12
WO2019110619A1 (en) 2019-06-13
JP2021505655A (ja) 2021-02-18
MX2020006284A (es) 2021-04-12
EP3720433B1 (en) 2022-02-02
SI3720433T1 (sl) 2022-09-30
AU2018379255B2 (en) 2024-10-17
EP4029498B1 (en) 2025-02-05
PT4029498T (pt) 2025-05-06
RU2020122023A (ru) 2022-01-10
IL275115B1 (en) 2025-06-01
EP3720433A1 (en) 2020-10-14
DK4029498T3 (da) 2025-04-28
JP2025066802A (ja) 2025-04-23
SI4029498T1 (sl) 2025-07-31
FI4029498T3 (fi) 2025-04-29
EP4523745A3 (en) 2025-05-14
US20210137972A1 (en) 2021-05-13
IL275115A (en) 2020-07-30
DK3720433T3 (da) 2022-05-02
HUE071155T2 (hu) 2025-08-28

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