PL3720433T3 - Tetratiomolibdenian bis-choliny do leczenia choroby wilsona - Google Patents

Tetratiomolibdenian bis-choliny do leczenia choroby wilsona

Info

Publication number
PL3720433T3
PL3720433T3 PL18815624.4T PL18815624T PL3720433T3 PL 3720433 T3 PL3720433 T3 PL 3720433T3 PL 18815624 T PL18815624 T PL 18815624T PL 3720433 T3 PL3720433 T3 PL 3720433T3
Authority
PL
Poland
Prior art keywords
bis
wilson disease
choline tetrathiomolybdate
treating wilson
treating
Prior art date
Application number
PL18815624.4T
Other languages
English (en)
Polish (pl)
Inventor
Aftab ALA
Carl BJARTMAR
Karl-Heinz Weiss
Michael SCHILSKY
Frederick ASKARI
Anna CZLONKOWSKA
Peter Ferenci
Peter HEDERA
Original Assignee
Alexion Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexion Pharmaceuticals, Inc. filed Critical Alexion Pharmaceuticals, Inc.
Publication of PL3720433T3 publication Critical patent/PL3720433T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL18815624.4T 2017-12-04 2018-12-04 Tetratiomolibdenian bis-choliny do leczenia choroby wilsona PL3720433T3 (pl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762594184P 2017-12-04 2017-12-04
US201862646553P 2018-03-22 2018-03-22
US201862655568P 2018-04-10 2018-04-10
US201862669095P 2018-05-09 2018-05-09
US201862741313P 2018-10-04 2018-10-04
US201862750595P 2018-10-25 2018-10-25
PCT/EP2018/083551 WO2019110619A1 (en) 2017-12-04 2018-12-04 Bis-choline tetrathiomolybdate for treating wilson disease

Publications (1)

Publication Number Publication Date
PL3720433T3 true PL3720433T3 (pl) 2022-07-18

Family

ID=64661349

Family Applications (2)

Application Number Title Priority Date Filing Date
PL21215264.9T PL4029498T3 (pl) 2017-12-04 2018-12-04 Tetrathiomolibdenian bis-choliny do leczenia choroby wilsona
PL18815624.4T PL3720433T3 (pl) 2017-12-04 2018-12-04 Tetratiomolibdenian bis-choliny do leczenia choroby wilsona

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL21215264.9T PL4029498T3 (pl) 2017-12-04 2018-12-04 Tetrathiomolibdenian bis-choliny do leczenia choroby wilsona

Country Status (17)

Country Link
US (3) US11510944B2 (enExample)
EP (3) EP4029498B1 (enExample)
JP (3) JP2021505655A (enExample)
KR (1) KR102803161B1 (enExample)
AU (1) AU2018379255B2 (enExample)
BR (1) BR112020011055A2 (enExample)
CA (1) CA3084100A1 (enExample)
DK (2) DK4029498T3 (enExample)
ES (2) ES3026756T3 (enExample)
FI (1) FI4029498T3 (enExample)
HU (2) HUE058921T2 (enExample)
IL (1) IL275115B2 (enExample)
MX (1) MX2020006284A (enExample)
PL (2) PL4029498T3 (enExample)
PT (2) PT4029498T (enExample)
SI (2) SI3720433T1 (enExample)
WO (1) WO2019110619A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018379255B2 (en) * 2017-12-04 2024-10-17 Alexion Pharma International Operations Unlimited Company Bis-choline tetrathiomolybdate for treating Wilson Disease
US11419832B2 (en) * 2017-12-04 2022-08-23 Alexion Pharmaceuticals, Inc. Bis-choline tetrathiomolybdate for treating Wilson Disease
WO2019154876A1 (en) 2018-02-06 2019-08-15 Wilson Therapeutics Ab Crystalline particles of bis-choline tetrathiomolybdate
US20220387370A1 (en) 2019-11-21 2022-12-08 Alexion Pharmaceuticals, Inc. Methods of reducing neurological damage in wilson disease patients
US20240044920A1 (en) * 2020-09-11 2024-02-08 Alexion Pharmaceuticals, Inc. Anti-ceruloplasmin antibodies and uses thereof
EP4243806A1 (en) 2020-11-13 2023-09-20 Alexion Pharmaceuticals, Inc. Methods of treating copper metabolism-associated diseases or disorders
US20240100088A1 (en) * 2021-01-31 2024-03-28 Alexion Pharmaceuticals, Inc. Novel formulation for treating copper metabolism-associated diseases or disorders
JP2024532131A (ja) * 2021-08-17 2024-09-05 アレクシオン ファーマシューティカルズ, インコーポレイテッド 銅代謝関連疾患又は障害を治療する方法
WO2024162974A1 (en) 2023-01-30 2024-08-08 Alexion Pharmaceuticals, Inc. Tetrathiomolybdic acid for use in treating copper metabolism-associated diseases or disorders (wilson disease)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189865B2 (en) * 2002-07-23 2007-03-13 Attenuon, Llc Thiomolybdate analogues and uses thereof
MXPA05000875A (es) * 2002-07-23 2005-09-30 Univ Michigan Tetratiomolibdato de tetrapropilamonio y compuestos relacionados para terapias anti-angiogenicas.
WO2007084818A2 (en) * 2006-01-10 2007-07-26 Pipex, Inc. Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases
US9623021B2 (en) 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
AU2018379255B2 (en) 2017-12-04 2024-10-17 Alexion Pharma International Operations Unlimited Company Bis-choline tetrathiomolybdate for treating Wilson Disease
US11419832B2 (en) * 2017-12-04 2022-08-23 Alexion Pharmaceuticals, Inc. Bis-choline tetrathiomolybdate for treating Wilson Disease
WO2019154876A1 (en) 2018-02-06 2019-08-15 Wilson Therapeutics Ab Crystalline particles of bis-choline tetrathiomolybdate

Also Published As

Publication number Publication date
JP2021505655A (ja) 2021-02-18
MX2020006284A (es) 2021-04-12
US20230070534A1 (en) 2023-03-09
EP4523745A3 (en) 2025-05-14
WO2019110619A1 (en) 2019-06-13
KR102803161B1 (ko) 2025-05-07
DK4029498T3 (da) 2025-04-28
EP3720433A1 (en) 2020-10-14
SI3720433T1 (sl) 2022-09-30
PT3720433T (pt) 2022-05-03
IL275115B2 (en) 2025-10-01
KR20200096798A (ko) 2020-08-13
ES2912306T3 (es) 2022-05-25
US20210137972A1 (en) 2021-05-13
DK3720433T3 (da) 2022-05-02
PL4029498T3 (pl) 2025-06-02
US11510944B2 (en) 2022-11-29
AU2018379255B2 (en) 2024-10-17
FI4029498T3 (fi) 2025-04-29
EP4523745A2 (en) 2025-03-19
HUE071155T2 (hu) 2025-08-28
IL275115A (en) 2020-07-30
JP2025066802A (ja) 2025-04-23
ES3026756T3 (en) 2025-06-12
PT4029498T (pt) 2025-05-06
RU2020122023A (ru) 2022-01-10
EP4029498A1 (en) 2022-07-20
AU2018379255A1 (en) 2020-06-25
SI4029498T1 (sl) 2025-07-31
CA3084100A1 (en) 2019-06-13
IL275115B1 (en) 2025-06-01
US20210177894A1 (en) 2021-06-17
JP2023075247A (ja) 2023-05-30
BR112020011055A2 (pt) 2020-11-17
US12233088B2 (en) 2025-02-25
EP3720433B1 (en) 2022-02-02
EP4029498B1 (en) 2025-02-05
HUE058921T2 (hu) 2022-09-28

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