PL3689351T3 - Pochodna chinoliny i zastosowanie jej jako inhibitor kinazy tyrozynowej - Google Patents
Pochodna chinoliny i zastosowanie jej jako inhibitor kinazy tyrozynowejInfo
- Publication number
- PL3689351T3 PL3689351T3 PL18862179.1T PL18862179T PL3689351T3 PL 3689351 T3 PL3689351 T3 PL 3689351T3 PL 18862179 T PL18862179 T PL 18862179T PL 3689351 T3 PL3689351 T3 PL 3689351T3
- Authority
- PL
- Poland
- Prior art keywords
- application
- tyrosine kinase
- kinase inhibitor
- quinoline derivative
- quinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710900497 | 2017-09-28 | ||
| CN201810732319 | 2018-07-05 | ||
| PCT/CN2018/106674 WO2019062637A1 (zh) | 2017-09-28 | 2018-09-20 | 喹啉衍生物及其作为酪氨酸激酶抑制剂的应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3689351T3 true PL3689351T3 (pl) | 2023-03-20 |
Family
ID=64813340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18862179.1T PL3689351T3 (pl) | 2017-09-28 | 2018-09-20 | Pochodna chinoliny i zastosowanie jej jako inhibitor kinazy tyrozynowej |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11161817B2 (pl) |
| EP (1) | EP3689351B1 (pl) |
| JP (1) | JP7177829B2 (pl) |
| CN (1) | CN109134365B (pl) |
| ES (1) | ES2932805T3 (pl) |
| PL (1) | PL3689351T3 (pl) |
| WO (1) | WO2019062637A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3689351T3 (pl) | 2017-09-28 | 2023-03-20 | Chongqing Pharmaceutical Industrial Research Institute Co. Ltd. | Pochodna chinoliny i zastosowanie jej jako inhibitor kinazy tyrozynowej |
| CN111592538A (zh) * | 2019-02-21 | 2020-08-28 | 南京明德新药研发有限公司 | 作为ret抑制剂的脂肪环衍生物 |
| WO2020187188A1 (zh) * | 2019-03-15 | 2020-09-24 | 南京明德新药研发有限公司 | 喹啉衍生物及免疫调节剂联合在制备抗肿瘤药物中的应用 |
| CN113135853A (zh) | 2020-01-19 | 2021-07-20 | 重庆医药工业研究院有限责任公司 | 一种氟伐替尼或甲磺酸盐的晶型及其制备方法 |
| CN113480479B (zh) * | 2021-08-12 | 2022-08-02 | 上海爱博医药科技有限公司 | 脲类多靶点酪氨酸激酶抑制剂及其医药应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60134679D1 (de) | 2000-10-20 | 2008-08-14 | Eisai R&D Man Co Ltd | Stickstoff enthaltende aromatische Heterozyklen |
| EP1856095B1 (en) | 2005-02-26 | 2011-08-24 | AstraZeneca AB | Quinazoline derivatives as tyrosine kinase inhibitors |
| CN101311166B (zh) | 2007-05-21 | 2011-03-09 | 李萍 | 酪氨酸激酶抑制剂及其制备药物的用途 |
| EP2621483A1 (en) | 2010-09-27 | 2013-08-07 | Exelixis, Inc. | Dual inhibitors of met and vegf for the treatment of castration resistant prostate cancer and osteoblastic bone metastases |
| MX2013012695A (es) | 2011-05-02 | 2014-03-27 | Exelixis Inc | Metodo para el tratamiento del cancer y el dolor por cancer de hueso. |
| EP3293177A4 (en) | 2015-04-07 | 2018-12-12 | Guangdong Zhongsheng Pharmaceutical Co., Ltd | Tyrosine kinase inhibitor and pharmaceutical composition comprising same |
| PL3689351T3 (pl) | 2017-09-28 | 2023-03-20 | Chongqing Pharmaceutical Industrial Research Institute Co. Ltd. | Pochodna chinoliny i zastosowanie jej jako inhibitor kinazy tyrozynowej |
-
2018
- 2018-09-20 PL PL18862179.1T patent/PL3689351T3/pl unknown
- 2018-09-20 JP JP2020517877A patent/JP7177829B2/ja active Active
- 2018-09-20 US US16/651,521 patent/US11161817B2/en active Active
- 2018-09-20 WO PCT/CN2018/106674 patent/WO2019062637A1/zh unknown
- 2018-09-20 EP EP18862179.1A patent/EP3689351B1/en active Active
- 2018-09-20 ES ES18862179T patent/ES2932805T3/es active Active
- 2018-09-28 CN CN201811140279.8A patent/CN109134365B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN109134365A (zh) | 2019-01-04 |
| CN109134365B (zh) | 2019-05-31 |
| JP2020535188A (ja) | 2020-12-03 |
| EP3689351A4 (en) | 2020-08-19 |
| WO2019062637A1 (zh) | 2019-04-04 |
| US20200262791A1 (en) | 2020-08-20 |
| ES2932805T3 (es) | 2023-01-26 |
| EP3689351A1 (en) | 2020-08-05 |
| JP7177829B2 (ja) | 2022-11-24 |
| US11161817B2 (en) | 2021-11-02 |
| EP3689351B1 (en) | 2022-11-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL279258B (en) | tyrosine kinase inhibitors | |
| IL268004B (en) | History of tyrosine amide as rho-kinase inhibitors | |
| EP3293177A4 (en) | Tyrosine kinase inhibitor and pharmaceutical composition comprising same | |
| SG11202004918XA (en) | Amino-fluoropiperidine derivative as kinase inhibitor | |
| IL268614A (en) | Aminotriazolopyridines as kinase inhibitors | |
| PL3689351T3 (pl) | Pochodna chinoliny i zastosowanie jej jako inhibitor kinazy tyrozynowej | |
| IL275207A (en) | An oxyfluoropiperidine derivative as a kinase inhibitor | |
| PT3447051T (pt) | Método para preparar um inibidor de tirosina quinase e um derivado do mesmo | |
| SG10201913927VA (en) | Kinase inhibitors and uses thereof | |
| HK1245678A1 (zh) | 使用酪氨酸激酶抑制劑的組合物和方法 | |
| EP3511327A4 (en) | TYROSINE KINASE INHIBITOR AND APPLICATION THEREOF | |
| HUE058292T2 (hu) | Aminoimidazopiridazinok mint kináz inhibitorok | |
| ZA201900606B (en) | Novel pyrazole derivative as alk5 inhibitor and uses thereof | |
| IL304547A (en) | 3-substituted benzamide derivatives as kinase inhibitors | |
| IL266840A (en) | History of tyrosine and preparations containing them | |
| EP3284746A4 (en) | Preparation and use of kinase inhibitor | |
| EP3896059C0 (en) | PAN-KIT KINASE INHIBITOR HAVING A QUINOLINE STRUCTURE AND USE THEREOF | |
| EP3699177A4 (en) | METHOD OF MANUFACTURING A TYROSINKINAS INHIBITOR AND INTERMEDIATE THEREOF | |
| IL272887A (en) | A pharmaceutical preparation containing a selective inhibitor of FGFR tyrosine kinase | |
| GB201705201D0 (en) | Novel compounds and their use as kinase inhibitors | |
| GB201609580D0 (en) | Novel compounds and their use as kinase inhibitors |