PL3654938T3 - Dyspersje stałe w postaci proszku zawierające kwercetynę, sposób ich wytwarzania i ich preparaty - Google Patents

Dyspersje stałe w postaci proszku zawierające kwercetynę, sposób ich wytwarzania i ich preparaty

Info

Publication number
PL3654938T3
PL3654938T3 PL18743743.9T PL18743743T PL3654938T3 PL 3654938 T3 PL3654938 T3 PL 3654938T3 PL 18743743 T PL18743743 T PL 18743743T PL 3654938 T3 PL3654938 T3 PL 3654938T3
Authority
PL
Poland
Prior art keywords
quercetin
formulations
preparation
solid dispersions
powder solid
Prior art date
Application number
PL18743743.9T
Other languages
English (en)
Inventor
Massimo Ronchi
Elisabetta FRATTINI
Antonella Riva
Original Assignee
Indena S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena S.P.A. filed Critical Indena S.P.A.
Publication of PL3654938T3 publication Critical patent/PL3654938T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
PL18743743.9T 2017-07-17 2018-07-16 Dyspersje stałe w postaci proszku zawierające kwercetynę, sposób ich wytwarzania i ich preparaty PL3654938T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17181634 2017-07-17
PCT/EP2018/069284 WO2019016146A1 (en) 2017-07-17 2018-07-16 SOLID POWDER DISPERSIONS COMPRISING QUERCETIN, PROCESS FOR PREPARING SAME AND FORMULAS THEREOF

Publications (1)

Publication Number Publication Date
PL3654938T3 true PL3654938T3 (pl) 2022-12-27

Family

ID=59381081

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18743743.9T PL3654938T3 (pl) 2017-07-17 2018-07-16 Dyspersje stałe w postaci proszku zawierające kwercetynę, sposób ich wytwarzania i ich preparaty

Country Status (18)

Country Link
US (1) US11331298B2 (pl)
EP (1) EP3654938B1 (pl)
JP (1) JP7284743B2 (pl)
KR (1) KR20200030076A (pl)
CN (1) CN110944624A (pl)
AU (1) AU2018304534A1 (pl)
BR (1) BR112020000841A2 (pl)
CA (1) CA3069055A1 (pl)
DK (1) DK3654938T3 (pl)
ES (1) ES2929981T3 (pl)
FI (1) FI3654938T3 (pl)
HU (1) HUE060387T2 (pl)
IL (1) IL271852B1 (pl)
PL (1) PL3654938T3 (pl)
PT (1) PT3654938T (pl)
SG (1) SG11202000141WA (pl)
SI (1) SI3654938T1 (pl)
WO (1) WO2019016146A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210393579A1 (en) * 2020-06-23 2021-12-23 Zestt Wellness Limited Anthocyanin and Quercetin Based Formulations for Improved Respiratory Health
JP7123434B1 (ja) 2021-03-17 2022-08-23 株式会社アイビー化粧品 破骨細胞分化抑制剤
CN113712988A (zh) * 2021-08-17 2021-11-30 塔里木大学 一种槲皮素-替米考星聚合物纳米微粒、其制备方法及应用
IT202200002108A1 (it) * 2022-02-07 2023-08-07 Indena Spa Composizioni a base di quercetina per il trattamento e la prevenzione di affezioni oculari
KR102653457B1 (ko) * 2023-12-20 2024-04-02 서울대학교산학협력단 장 점막 부착성이 향상된 쿼세틴 함유 분말 제제의 제조방법 및 이에 따라 제조된 쿼세틴 함유 분말 제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100370968C (zh) * 2005-12-06 2008-02-27 四川大学 槲皮素长效脂质体粉针剂及其制备方法
CN100367953C (zh) * 2006-03-06 2008-02-13 山东大学 槲皮素固体脂质纳米粒制剂及其制备方法
CN101904821A (zh) 2009-06-02 2010-12-08 姜玲敏 槲皮素纳米冻干粉及其制备方法
CN102058536A (zh) 2011-01-14 2011-05-18 四川大学 槲皮素羟丙基β-环糊精包和物脂质体及其制备方法和用途

Also Published As

Publication number Publication date
EP3654938B1 (en) 2022-08-31
RU2020106924A3 (pl) 2021-11-17
FI3654938T3 (fi) 2022-12-15
SG11202000141WA (en) 2020-02-27
KR20200030076A (ko) 2020-03-19
IL271852A (en) 2020-02-27
US20200206186A1 (en) 2020-07-02
RU2020106924A (ru) 2021-08-17
WO2019016146A1 (en) 2019-01-24
AU2018304534A1 (en) 2020-02-06
CA3069055A1 (en) 2019-01-24
CN110944624A (zh) 2020-03-31
ES2929981T3 (es) 2022-12-05
DK3654938T3 (da) 2022-10-03
PT3654938T (pt) 2022-11-03
US11331298B2 (en) 2022-05-17
IL271852B1 (en) 2024-03-01
SI3654938T1 (sl) 2022-11-30
BR112020000841A2 (pt) 2020-07-21
JP7284743B2 (ja) 2023-05-31
JP2020527549A (ja) 2020-09-10
HUE060387T2 (hu) 2023-02-28
EP3654938A1 (en) 2020-05-27

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