PL358811A1 - High order nucleic acid based structures - Google Patents

High order nucleic acid based structures

Info

Publication number
PL358811A1
PL358811A1 PL00358811A PL35881100A PL358811A1 PL 358811 A1 PL358811 A1 PL 358811A1 PL 00358811 A PL00358811 A PL 00358811A PL 35881100 A PL35881100 A PL 35881100A PL 358811 A1 PL358811 A1 PL 358811A1
Authority
PL
Poland
Prior art keywords
nucleic acid
high order
acid based
based structures
order nucleic
Prior art date
Application number
PL00358811A
Other languages
Polish (pl)
Inventor
Frank J. Carr
Graham Carter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9926810.4A external-priority patent/GB9926810D0/en
Priority claimed from GB0011126A external-priority patent/GB0011126D0/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL358811A1 publication Critical patent/PL358811A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
    • C12N2310/151—Nucleic acids forming more than 2 strands, e.g. TFOs more than 3 strands, e.g. tetrads, H-DNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/52—Physical structure branched
PL00358811A 1999-11-13 2000-11-13 High order nucleic acid based structures PL358811A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9926810.4A GB9926810D0 (en) 1999-11-13 1999-11-13 High order nucleic acid-based structures
GB0011126A GB0011126D0 (en) 2000-05-10 2000-05-10 High order nucleic acid-based structures
PCT/EP2000/011197 WO2001036624A1 (en) 1999-11-13 2000-11-13 High order nucleic acid based structures

Publications (1)

Publication Number Publication Date
PL358811A1 true PL358811A1 (en) 2004-08-23

Family

ID=26244234

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00358811A PL358811A1 (en) 1999-11-13 2000-11-13 High order nucleic acid based structures

Country Status (16)

Country Link
EP (1) EP1228201A1 (en)
JP (1) JP2003522524A (en)
KR (1) KR20020059727A (en)
CN (1) CN1390253A (en)
AU (1) AU782880B2 (en)
BR (1) BR0015484A (en)
CA (1) CA2391084A1 (en)
CZ (1) CZ20021472A3 (en)
HK (1) HK1052529A1 (en)
HU (1) HUP0203914A2 (en)
MX (1) MXPA02004727A (en)
NO (1) NO20022231D0 (en)
PL (1) PL358811A1 (en)
RU (1) RU2002113755A (en)
SK (1) SK6042002A3 (en)
WO (1) WO2001036624A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2358385C (en) 1998-12-31 2013-08-06 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
JP5033303B2 (en) 2001-07-05 2012-09-26 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Polynucleotides encoding polypeptides with antigenic type C HIV, polypeptides and uses thereof
KR20140054179A (en) 2011-08-05 2014-05-08 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Compositions and methods relating to nucleic acid nano- and micro-technology
KR20160073936A (en) 2012-07-24 2016-06-27 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Self-assembly of nucleic acid nanostructures
US9975916B2 (en) 2012-11-06 2018-05-22 President And Fellows Of Harvard College Compositions and methods relating to complex nucleic acid nanostructures
CN105705143A (en) * 2013-11-08 2016-06-22 达娜-法勃肿瘤研究所公司 Nucleic acid nanostructures for in vivo agent delivery
CN106488883A (en) 2014-05-22 2017-03-08 哈佛学院院长及董事 The extendible nanometer manufacture based on nucleic acid
WO2017156264A1 (en) 2016-03-11 2017-09-14 Children's Medical Center Corporation Nucleic acid nanoswitch catenanes
EP4071159B1 (en) 2016-08-02 2023-12-13 President and Fellows of Harvard College Crisscross cooperative self-assembly
KR102656600B1 (en) * 2018-07-12 2024-04-15 바이 야오 쥐 다 (베이징) 나노바이오 테크놀로지 컴퍼니 리미티드 Nucleic acid nanoparticles, drug composition containing the same, doxorubicin-containing drug, and method for producing the same
CN110711254B (en) * 2018-07-12 2022-07-26 百药智达（北京）纳米生物技术有限公司 Nucleic acid nanoparticles and pharmaceutical compositions comprising the same
CN110960536B (en) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 Aspirin-containing medicine, preparation method, pharmaceutical composition and application thereof
CN110960534B (en) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicine containing pentafluorouracil, preparation method thereof, pharmaceutical composition and application thereof
CN110960690B (en) * 2018-09-30 2022-07-22 百药智达（北京）纳米生物技术有限公司 Medicine containing epirubicin, preparation method thereof, pharmaceutical composition and application thereof
CN110960542B (en) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicament containing pirarubicin, preparation method thereof, pharmaceutical composition and application thereof
CN110960530B (en) * 2018-09-30 2022-07-22 百药智达（北京）纳米生物技术有限公司 Tacrine-containing medicine, preparation method thereof, pharmaceutical composition and application thereof
CN111053765B (en) * 2018-10-16 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicine containing paclitaxel, preparation method, pharmaceutical composition and application thereof
CN111068065B (en) * 2018-10-22 2022-07-26 百药智达（北京）纳米生物技术有限公司 Drug containing oxaliplatin, preparation method thereof, pharmaceutical composition and application thereof
CN111084887B (en) * 2018-10-23 2022-07-22 百药智达（北京）纳米生物技术有限公司 Flavone-containing medicine, preparation method thereof, medicine composition and application
CN111096965B (en) * 2018-10-29 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicine containing dihydroartemisinin, preparation method thereof, medicine composition and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151631A1 (en) * 1983-08-03 1985-08-21 The Research Foundation Of State University Of New York Nucleic acid branched junctions with precisely defined migrational mobility
US5386020A (en) * 1991-01-10 1995-01-31 New York University Multiply connected, three-dimensional nucleic acid structures
US5278051A (en) * 1991-12-12 1994-01-11 New York University Construction of geometrical objects from polynucleotides
US6072044A (en) * 1996-04-26 2000-06-06 New York University Nanoconstructions of geometrical objects and lattices from antiparallel nucleic acid double crossover molecules

Also Published As

Publication number Publication date
JP2003522524A (en) 2003-07-29
SK6042002A3 (en) 2002-12-03
AU782880B2 (en) 2005-09-08
EP1228201A1 (en) 2002-08-07
WO2001036624A1 (en) 2001-05-25
NO20022231L (en) 2002-05-10
KR20020059727A (en) 2002-07-13
AU2000101A (en) 2001-05-30
NO20022231D0 (en) 2002-05-10
MXPA02004727A (en) 2002-08-30
HUP0203914A2 (en) 2003-03-28
HK1052529A1 (en) 2003-09-19
CZ20021472A3 (en) 2002-07-17
CN1390253A (en) 2003-01-08
BR0015484A (en) 2002-07-02
CA2391084A1 (en) 2001-05-25
RU2002113755A (en) 2004-01-10

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)