HK1052529A1 - High order nucleic acid based structures - Google Patents

High order nucleic acid based structures

Info

Publication number
HK1052529A1
HK1052529A1 HK03104743.9A HK03104743A HK1052529A1 HK 1052529 A1 HK1052529 A1 HK 1052529A1 HK 03104743 A HK03104743 A HK 03104743A HK 1052529 A1 HK1052529 A1 HK 1052529A1
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
high order
acid based
based structures
order nucleic
Prior art date
Application number
HK03104743.9A
Other languages
Chinese (zh)
Inventor
J Carr Frank
Carter Graham
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9926810.4A external-priority patent/GB9926810D0/en
Priority claimed from GB0011126A external-priority patent/GB0011126D0/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HK1052529A1 publication Critical patent/HK1052529A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
    • C12N2310/151—Nucleic acids forming more than 2 strands, e.g. TFOs more than 3 strands, e.g. tetrads, H-DNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/52—Physical structure branched
HK03104743.9A 1999-11-13 2003-07-03 High order nucleic acid based structures HK1052529A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9926810.4A GB9926810D0 (en) 1999-11-13 1999-11-13 High order nucleic acid-based structures
GB0011126A GB0011126D0 (en) 2000-05-10 2000-05-10 High order nucleic acid-based structures
PCT/EP2000/011197 WO2001036624A1 (en) 1999-11-13 2000-11-13 High order nucleic acid based structures

Publications (1)

Publication Number Publication Date
HK1052529A1 true HK1052529A1 (en) 2003-09-19

Family

ID=26244234

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03104743.9A HK1052529A1 (en) 1999-11-13 2003-07-03 High order nucleic acid based structures

Country Status (16)

Country Link
EP (1) EP1228201A1 (en)
JP (1) JP2003522524A (en)
KR (1) KR20020059727A (en)
CN (1) CN1390253A (en)
AU (1) AU782880B2 (en)
BR (1) BR0015484A (en)
CA (1) CA2391084A1 (en)
CZ (1) CZ20021472A3 (en)
HK (1) HK1052529A1 (en)
HU (1) HUP0203914A2 (en)
MX (1) MXPA02004727A (en)
NO (1) NO20022231L (en)
PL (1) PL358811A1 (en)
RU (1) RU2002113755A (en)
SK (1) SK6042002A3 (en)
WO (1) WO2001036624A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000039304A2 (en) 1998-12-31 2000-07-06 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
JP5033303B2 (en) 2001-07-05 2012-09-26 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Polynucleotides encoding polypeptides with antigenic type C HIV, polypeptides and uses thereof
US9796749B2 (en) 2011-08-05 2017-10-24 President And Fellows Of Harvard College Compositions and methods relating to nucleic acid nano- and micro-technology
US10604543B2 (en) 2012-07-24 2020-03-31 President And Fellows Of Harvard College Self-assembly of nucleic acid nanostructures
WO2014074597A1 (en) 2012-11-06 2014-05-15 President And Fellows Of Harvard College Compositions and methods relating to complex nucleic acid nanostructures
CN105705143A (en) * 2013-11-08 2016-06-22 达娜-法勃肿瘤研究所公司 Nucleic acid nanostructures for in vivo agent delivery
KR20170009929A (en) 2014-05-22 2017-01-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Scalable nucleic acid-based nanofabrication
US11414694B2 (en) 2016-03-11 2022-08-16 Children's Medical Center Corporation Nucleic acid nanoswitch catenanes
US11254972B2 (en) 2016-08-02 2022-02-22 President And Fellows Of Harvard College Crisscross cooperative self-assembly
TWI743518B (en) * 2018-07-12 2021-10-21 大陸商百藥智達（北京）納米生物技術有限公司 Nucleic acid nanoparticles, pharmaceutical composition thereof, medicine comprising doxorubicin and preparation method thereof
CN110711254B (en) * 2018-07-12 2022-07-26 百药智达（北京）纳米生物技术有限公司 Nucleic acid nanoparticles and pharmaceutical compositions comprising the same
CN110960534B (en) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicine containing pentafluorouracil, preparation method thereof, pharmaceutical composition and application thereof
CN110960542B (en) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicament containing pirarubicin, preparation method thereof, pharmaceutical composition and application thereof
CN110960530B (en) * 2018-09-30 2022-07-22 百药智达（北京）纳米生物技术有限公司 Tacrine-containing medicine, preparation method thereof, pharmaceutical composition and application thereof
CN110960536B (en) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 Aspirin-containing medicine, preparation method, pharmaceutical composition and application thereof
CN110960690B (en) * 2018-09-30 2022-07-22 百药智达（北京）纳米生物技术有限公司 Medicine containing epirubicin, preparation method thereof, pharmaceutical composition and application thereof
CN111053765B (en) * 2018-10-16 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicine containing paclitaxel, preparation method, pharmaceutical composition and application thereof
CN111068065B (en) * 2018-10-22 2022-07-26 百药智达（北京）纳米生物技术有限公司 Drug containing oxaliplatin, preparation method thereof, pharmaceutical composition and application thereof
CN111084887B (en) * 2018-10-23 2022-07-22 百药智达（北京）纳米生物技术有限公司 Flavone-containing medicine, preparation method thereof, medicine composition and application
CN111096965B (en) * 2018-10-29 2022-07-26 百药智达（北京）纳米生物技术有限公司 Medicine containing dihydroartemisinin, preparation method thereof, medicine composition and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000813A1 (en) * 1983-08-03 1985-02-28 The Research Foundation Of State University Of New Nucleic acid branched junctions with precisely defined migrational mobility
US5386020A (en) * 1991-01-10 1995-01-31 New York University Multiply connected, three-dimensional nucleic acid structures
US5278051A (en) * 1991-12-12 1994-01-11 New York University Construction of geometrical objects from polynucleotides
US6072044A (en) * 1996-04-26 2000-06-06 New York University Nanoconstructions of geometrical objects and lattices from antiparallel nucleic acid double crossover molecules

Also Published As

Publication number Publication date
CN1390253A (en) 2003-01-08
NO20022231D0 (en) 2002-05-10
MXPA02004727A (en) 2002-08-30
JP2003522524A (en) 2003-07-29
EP1228201A1 (en) 2002-08-07
HUP0203914A2 (en) 2003-03-28
AU782880B2 (en) 2005-09-08
WO2001036624A1 (en) 2001-05-25
NO20022231L (en) 2002-05-10
CA2391084A1 (en) 2001-05-25
PL358811A1 (en) 2004-08-23
KR20020059727A (en) 2002-07-13
CZ20021472A3 (en) 2002-07-17
SK6042002A3 (en) 2002-12-03
AU2000101A (en) 2001-05-30
BR0015484A (en) 2002-07-02
RU2002113755A (en) 2004-01-10

Similar Documents

Publication Publication Date Title
PL343518A1 (en) (4-arylsulfonylamino)-tetrahydropyran-4-carboxylic acid hydroxamides
HUP0202221A1 (en) Tenascin-c nucleic acid lagands
HUP0201438A2 (en) Dna vaccine - pcv
IL149491A0 (en) Nucleic acid-containing complex
PL358811A1 (en) High order nucleic acid based structures
EP1114827A4 (en) Novel nucleic acid base pair
HUP0105208A3 (en) Gene therapy-1
HUP0203848A3 (en) Nucleic acid vaccination
IL146332A0 (en) PrP-LIKE GENE
IL149679A0 (en) Nucleic acid construct and methods utilizing the same
GB9917875D0 (en) Nucleic acid constructs
GB9905644D0 (en) Dna
EP1215284A4 (en) Tsg-like gene
IL132710A0 (en) Catalytic nucleic acid sequences
GB9823481D0 (en) Nucleic acid
GB9822490D0 (en) Nucleic acid
EP1218036A4 (en) Cell based assay
IL130606A0 (en) An array of nucleic acid sequence
AUPQ403299A0 (en) Nucleic acid sequence
AU4107500A (en) Nucleic acid combination
GB0026731D0 (en) Nucleic acid modification
GB0023519D0 (en) Nucleic acid modification
IL128483A0 (en) Nucleic acid molecules
AUPQ423599A0 (en) Novel nucleic acid molecules - II
GB9925696D0 (en) Detecting nucleic acid