PL3541784T3 - Nowe pochodne azetydyny użyteczne jako modulatory korowego nuroprzekaźnictwa katecholaminergicznego - Google Patents

Nowe pochodne azetydyny użyteczne jako modulatory korowego nuroprzekaźnictwa katecholaminergicznego

Info

Publication number
PL3541784T3
PL3541784T3 PL17807779.8T PL17807779T PL3541784T3 PL 3541784 T3 PL3541784 T3 PL 3541784T3 PL 17807779 T PL17807779 T PL 17807779T PL 3541784 T3 PL3541784 T3 PL 3541784T3
Authority
PL
Poland
Prior art keywords
modulators
derivatives useful
azetidine derivatives
novel azetidine
cortical
Prior art date
Application number
PL17807779.8T
Other languages
English (en)
Polish (pl)
Inventor
Clas Sonesson
Fredrik Pettersson
Original Assignee
Integrative Research Laboratories Sweden Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Integrative Research Laboratories Sweden Ab filed Critical Integrative Research Laboratories Sweden Ab
Publication of PL3541784T3 publication Critical patent/PL3541784T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL17807779.8T 2016-11-18 2017-11-17 Nowe pochodne azetydyny użyteczne jako modulatory korowego nuroprzekaźnictwa katecholaminergicznego PL3541784T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16199545 2016-11-18
PCT/EP2017/079666 WO2018091687A1 (en) 2016-11-18 2017-11-17 Novel azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission

Publications (1)

Publication Number Publication Date
PL3541784T3 true PL3541784T3 (pl) 2024-03-11

Family

ID=57348567

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17807779.8T PL3541784T3 (pl) 2016-11-18 2017-11-17 Nowe pochodne azetydyny użyteczne jako modulatory korowego nuroprzekaźnictwa katecholaminergicznego

Country Status (10)

Country Link
US (1) US10875829B1 (https=)
EP (1) EP3541784B1 (https=)
JP (1) JP6990702B2 (https=)
CN (1) CN109963834B (https=)
DK (1) DK3541784T5 (https=)
ES (1) ES2962865T3 (https=)
FI (1) FI3541784T3 (https=)
PL (1) PL3541784T3 (https=)
PT (1) PT3541784T (https=)
WO (1) WO2018091687A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112198237B (zh) * 2020-05-28 2021-08-06 扬子江药业集团广州海瑞药业有限公司 一种盐酸奈康唑杂质检测控制分析方法
KR20260033016A (ko) 2023-07-06 2026-03-10 인터그레이티브 리서치 래버러토리즈 스웨덴 에이비 병리적 무관심의 치료 및/또는 예방에 사용하기 위한 3-(2,3-디플루오로페녹시)아제티딘 또는 이의 약제학적으로 허용되는 염
CN121548563A (zh) 2023-07-06 2026-02-17 综合研究实验室瑞典股份公司 3-(2,3-二氟苯氧基)氮杂环丁烷的药学上可接受的盐及其用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004113297A2 (en) * 2003-06-24 2004-12-29 Neurosearch A/S Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
AP2007004047A0 (en) 2005-01-20 2007-06-30 Pfizer Ltd Substituted triazole derivatives as oxtocin antagonists
WO2007148185A2 (en) 2006-06-21 2007-12-27 Pfizer Products Inc. Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
WO2010022055A2 (en) 2008-08-20 2010-02-25 Amgen Inc. Inhibitors of voltage-gated sodium channels
CA2744308C (en) 2008-11-24 2017-05-30 Nsab, Filial Af Neurosearch Sweden Ab, Sverige 3-phenyl-3-methoxypyrrolidine derivatives as modulators of cortical catecholaminergic neurotransmission
MX2011005034A (es) 2008-11-24 2011-06-16 Nsab Af Neurosearch Sweden Ab Nuevos derivados de 3-fenil-azetidina utiles como moduladores de la neurotransmision catecolaminergica cortical.
EP2389374A1 (en) 2009-01-20 2011-11-30 Pfizer Inc. Substituted pyrazinone amides
TWI404721B (zh) * 2009-01-26 2013-08-11 Pfizer 胺基-雜環化合物
WO2011103196A1 (en) 2010-02-17 2011-08-25 Amgen Inc. Aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain
CA2836851C (en) 2011-06-07 2016-06-21 Christopher J. Helal Pyrazolo[3,4-d]pyrimidine compounds and their use as pde2 inhibitors and/or cyp3a4 inhibitors
KR101273566B1 (ko) 2011-09-05 2013-06-11 한국과학기술연구원 신규한 아제티딘 유도체 및 이를 함유하는 항우울제 조성물
BR112014018199A8 (pt) * 2012-01-26 2021-03-02 H Lundbeck As inibidores da pde9 com cadeia principal imidazo triazinona, composição farmacêutica que os compreende, uso dos referidos inibidores e processo para sua preparação
RU2017107521A (ru) 2014-08-27 2018-10-01 Ф. Хоффманн-Ля Рош Аг Замещенные производные азетидина в качестве лигандов рецепторов следовых аминов taar
EP3215500A1 (en) * 2014-11-05 2017-09-13 Dart NeuroScience (Cayman) Ltd. Substituted azetidinyl compounds as glyt1 inhibitors
PT3297987T (pt) * 2015-05-20 2019-06-19 Integrative Res Laboratories Sweden Ab Novos derivados de azetidina úteis como moduladores da neurotransmissão catecolaminérgica cortical
CN108026030B (zh) 2015-09-18 2020-10-09 正大天晴药业集团股份有限公司 一种氘代化合物的制备方法
TWI752098B (zh) * 2016-10-10 2022-01-11 美商亞雷生物製藥股份有限公司 作為ret激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物

Also Published As

Publication number Publication date
WO2018091687A1 (en) 2018-05-24
JP2019535715A (ja) 2019-12-12
US10875829B1 (en) 2020-12-29
CN109963834A (zh) 2019-07-02
DK3541784T3 (en) 2023-10-23
FI3541784T3 (fi) 2023-10-02
EP3541784B1 (en) 2023-09-13
ES2962865T3 (es) 2024-03-21
EP3541784A1 (en) 2019-09-25
CN109963834B (zh) 2023-04-14
PT3541784T (pt) 2023-11-22
DK3541784T5 (da) 2024-09-16
JP6990702B2 (ja) 2022-01-13

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