PL344534A1 - Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment - Google Patents

Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment

Info

Publication number
PL344534A1
PL344534A1 PL98344534A PL34453498A PL344534A1 PL 344534 A1 PL344534 A1 PL 344534A1 PL 98344534 A PL98344534 A PL 98344534A PL 34453498 A PL34453498 A PL 34453498A PL 344534 A1 PL344534 A1 PL 344534A1
Authority
PL
Poland
Prior art keywords
diagnosis
tools
recognized
treatment
rheumatoid arthritis
Prior art date
Application number
PL98344534A
Other languages
English (en)
Inventor
Lydie Meheus
Ann Union
Joseph Raymackers
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98870078A external-priority patent/EP0949270A1/en
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Publication of PL344534A1 publication Critical patent/PL344534A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL98344534A 1997-11-28 1998-11-30 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment PL344534A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97870195 1997-11-28
EP98870078A EP0949270A1 (en) 1998-04-09 1998-04-09 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
PCT/EP1998/007714 WO1999028344A2 (en) 1997-11-28 1998-11-30 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment

Publications (1)

Publication Number Publication Date
PL344534A1 true PL344534A1 (en) 2001-11-05

Family

ID=26148315

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98344534A PL344534A1 (en) 1997-11-28 1998-11-30 Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment

Country Status (8)

Country Link
EP (1) EP1034186A2 (xx)
JP (1) JP2002512939A (xx)
AU (1) AU2155899A (xx)
CA (1) CA2309534A1 (xx)
CZ (1) CZ20001963A3 (xx)
HU (1) HUP0004338A2 (xx)
PL (1) PL344534A1 (xx)
WO (1) WO1999028344A2 (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7184426B2 (en) 2002-12-12 2007-02-27 Qualcomm, Incorporated Method and apparatus for burst pilot for a time division multiplex system
FR2773078B1 (fr) * 1997-12-30 2000-05-26 Univ Toulouse Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide
ES2174770T1 (es) * 1999-12-21 2002-11-16 Innogenetics Nv Peptidos diseñados para el diagnostico y el tratamiento de artritis reumatoide.
FR2826124B1 (fr) 2001-06-13 2004-01-02 Bio Merieux Procede de detection d'auto-anticorps specifiques de la polyarthrite rhumatoide
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
CN1809753B (zh) * 2003-07-29 2010-10-20 索尔瓦药物有限公司 通过二维凝胶电泳分析包含生理可接受消化酶混合物的方法
AT413768B (de) * 2003-07-29 2006-05-15 Herkner Kurt Dipl Ing Dr Techn Biochemisches diagnostikum zur erkennung rheumatoider arthritis
DK1882946T3 (da) * 2003-12-23 2010-05-31 Hoffmann La Roche Fremgangsmåde til at bedømme rheumatold arthritis ved at måle anti-CCP og interleukin 6
CA2552420A1 (en) 2004-02-27 2005-09-15 F. Hoffmann-La Roche Ag Method of assessing rheumatoid arthritis by measuring anti-ccp and serum amyloid a
JP5140586B2 (ja) 2005-07-29 2013-02-06 アボット プロダクツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 滅菌パンクレアチン粉末の製法
US9198871B2 (en) 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
US11266607B2 (en) 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
GB0525492D0 (en) * 2005-12-15 2006-01-25 Univ Dundee Filaggrin
FR2900657B1 (fr) * 2006-05-03 2009-04-17 Univ Toulouse Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
US10072256B2 (en) 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
WO2008037420A1 (en) 2006-09-29 2008-04-03 Roche Diagnostics Gmbh Assessing the risk of disease progression for a patient with rheumatoid arthritis
JP5611831B2 (ja) * 2007-12-03 2014-10-22 エスキューアイ・ダイアグノスティクス・システムズ・インコーポレイテッドＳＱＩ Ｄｉａｇｎｏｓｔｉｃｓ Ｓｙｓｔｅｍｓ Ｉｎｃ． リウマチ性関節炎自己抗体との免疫反応性合成ペプチド
NO2294086T3 (xx) * 2008-06-04 2018-02-10
IL225538A0 (en) 2009-03-30 2013-06-27 Nestec Sa Methods for the identification of anti-immune reaction peptides of anti-citrullinates
EP2325195A1 (en) 2009-11-23 2011-05-25 Toscana Biomarkers S.r.l. Viral citrullinated peptides and uses thereof
EP2336769A1 (en) 2009-12-18 2011-06-22 F. Hoffmann-La Roche AG Trigger assay for differentiating between rheumatic and non-rheumatic disorders
EP2402368A1 (en) 2010-07-02 2012-01-04 Toscana Biomarkers S.r.l. Histone citrullinated peptides and uses thereof
EP2527841A1 (en) 2011-05-25 2012-11-28 Toscana Biomarkers S.r.l. Methods for the diagnosis of rheumatoid arthritis
CN103703370B (zh) * 2011-05-27 2016-08-17 北欧生物科技公司 诊断性肽的检测
WO2013024881A1 (ja) * 2011-08-12 2013-02-21 国立大学法人広島大学 アスベスト検出方法
AU2012353660A1 (en) 2011-12-16 2014-06-12 Olema Pharmaceuticals, Inc. Novel benzopyran compounds, compositions and uses thereof
WO2014141244A1 (en) * 2013-03-12 2014-09-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Synthetic peptides for the treatment of autoimmune diseases
EP3024849A2 (en) 2013-07-24 2016-06-01 Vilara AB Novel antibodies for the diagnosis and treatment of rheumatoid arthritis
KR101634958B1 (ko) * 2014-06-13 2016-06-30 한국생명공학연구원 필라그린 유전자 돌연변이 검출용 프로브, 키트 및 방법
EP3056903A1 (en) 2015-02-13 2016-08-17 F. Hoffmann-La Roche AG Method of assessing rheumatoid arthritis by measuring anti-CCP and anti-Casp8
JP2018506720A (ja) 2015-02-13 2018-03-08 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 抗ｃｃｐおよび抗ｐｉｋ３ｃｄを測定することによる関節リウマの査定方法
EP3056904A1 (en) 2015-02-13 2016-08-17 F. Hoffmann-La Roche AG Method of assessing rheumatoid arthritis by measuring anti-CCP and anti-MCM3
CN111007262A (zh) * 2019-12-25 2020-04-14 漳州卫生职业学院 一种用于辅助诊断ra的试剂盒及检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660994A (en) * 1986-11-10 1997-08-26 Progen Biotechnik Gmbh Method of detecting tissue-specific, insoluble cytoskeletal proteins
EP0511116B1 (fr) * 1991-04-26 2004-06-16 Clonatec S.A. Antigènes reconnus par des anticorps de la polyarthrite rhumatoide, leur préparation et leurs applications
FR2752842B1 (fr) * 1996-08-30 1998-11-06 Biomerieux Sa Antigenes derives des filaggrines et leur utilisation pour le diagnostic de la polyarthrite rhumatoide
NL1004539C2 (nl) * 1996-11-15 1998-05-20 Stichting Tech Wetenschapp Peptide afgeleid van een door auto-antilichamen van patiënten met reumatoïde artritis herkend antigeen, antilichaam daartegen en werkwijze voor het detecteren van auto-immuunantilichamen.

Also Published As

Publication number Publication date
CZ20001963A3 (cs) 2002-04-17
WO1999028344A2 (en) 1999-06-10
AU2155899A (en) 1999-06-16
EP1034186A2 (en) 2000-09-13
WO1999028344A3 (en) 1999-08-12
HUP0004338A2 (hu) 2001-02-28
CA2309534A1 (en) 1999-06-10
JP2002512939A (ja) 2002-05-08

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