PL3368652T3 - Monitorowanie odchyleń od stanu w bioreaktorach - Google Patents

Monitorowanie odchyleń od stanu w bioreaktorach

Info

Publication number
PL3368652T3
PL3368652T3 PL16788131T PL16788131T PL3368652T3 PL 3368652 T3 PL3368652 T3 PL 3368652T3 PL 16788131 T PL16788131 T PL 16788131T PL 16788131 T PL16788131 T PL 16788131T PL 3368652 T3 PL3368652 T3 PL 3368652T3
Authority
PL
Poland
Prior art keywords
bioreactors
monitoring state
state deviations
deviations
monitoring
Prior art date
Application number
PL16788131T
Other languages
English (en)
Inventor
Christian Klinger
Detlef Eisenkraetzer
Katrin GREPPMAIR
Claudia SCHMIDBERGER
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3368652T3 publication Critical patent/PL3368652T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/404—Cells with anode, cathode and cell electrolyte on the same side of a permeable membrane which separates them from the sample fluid, e.g. Clark-type oxygen sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Computer Hardware Design (AREA)
  • Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Electrotherapy Devices (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL16788131T 2015-10-30 2016-10-28 Monitorowanie odchyleń od stanu w bioreaktorach PL3368652T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15192387 2015-10-30
EP16788131.7A EP3368652B1 (en) 2015-10-30 2016-10-28 Monitoring state deviations in bioreactors
PCT/EP2016/076167 WO2017072340A1 (en) 2015-10-30 2016-10-28 Monitoring state deviations in bioreactors

Publications (1)

Publication Number Publication Date
PL3368652T3 true PL3368652T3 (pl) 2022-04-04

Family

ID=54364191

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16788131T PL3368652T3 (pl) 2015-10-30 2016-10-28 Monitorowanie odchyleń od stanu w bioreaktorach

Country Status (9)

Country Link
US (1) US11473042B2 (pl)
EP (1) EP3368652B1 (pl)
JP (2) JP7338971B2 (pl)
CN (1) CN108138111B (pl)
ES (1) ES2906617T3 (pl)
HR (1) HRP20220153T1 (pl)
PL (1) PL3368652T3 (pl)
SI (1) SI3368652T1 (pl)
WO (1) WO2017072340A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2554334A (en) 2016-05-17 2018-04-04 Tap Biosystems Phc Ltd Automated bioprocess development
WO2020076894A2 (en) * 2018-10-09 2020-04-16 Telhan Orkan M Portable bioreactors and portable bioreactor systems for analyzing biofilm formation and degradation
EP3868860B1 (en) * 2020-02-21 2025-04-23 Sartorius Stedim Data Analytics AB Computer-implemented method, computer program product and system for simulating a cell culture process
US11299700B1 (en) 2021-02-19 2022-04-12 Acequia Biotechnology, Llc Bioreactor containers and methods of growing hairy roots using the same
KR20250099137A (ko) 2022-11-02 2025-07-01 에프. 호프만-라 로슈 아게 당단백질 조성물의 생산 방법
TR2022021647A1 (tr) * 2022-12-30 2024-07-22 Ondokuz Mayis Ueniversitesi Atmosferik karbon tutucu sistem.
CN116300479B (zh) * 2023-05-22 2023-08-22 山东卫康生物医药科技有限公司 基于干细胞培养法的人参皂甙生产装置的控制方法及系统
WO2025224236A1 (en) * 2024-04-25 2025-10-30 F. Hoffmann-La Roche Ag Methods and systems for determining an actual ph in a liquid phase of a tank
CN118184082B (zh) * 2024-05-15 2024-08-30 四川省科源工程技术测试中心有限责任公司 一种垃圾填埋场污染渗滤液的净化系统及方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60141286A (ja) 1983-12-28 1985-07-26 Ajinomoto Co Inc 動物細胞の培養方法および装置
US4513280A (en) * 1984-10-04 1985-04-23 The United States Of America As Represented By The Secretary Of The Navy Method and apparatus for the detection of toxicants
CN1238498C (zh) * 2004-02-12 2006-01-25 陈志南 动物细胞无血清悬浮培养工艺过程控制参数的方法
WO2007085880A1 (en) 2006-01-28 2007-08-02 Abb Research Ltd A method for on-line prediction of future performance of a fermentation unit.
US8178318B2 (en) * 2008-08-06 2012-05-15 Praxair Technology, Inc. Method for controlling pH, osmolality and dissolved carbon dioxide levels in a mammalian cell culture process to enhance cell viability and biologic product yield
SG2014008809A (en) 2011-09-21 2014-04-28 Hoffmann La Roche Co2 profile cultivation
CN103649299B (zh) * 2011-10-28 2016-10-12 西门子公司 生产过程的监控系统及其控制方法

Also Published As

Publication number Publication date
ES2906617T3 (es) 2022-04-19
HK1252112A1 (zh) 2019-05-17
EP3368652B1 (en) 2021-12-15
WO2017072340A1 (en) 2017-05-04
JP2018533936A (ja) 2018-11-22
CN108138111A (zh) 2018-06-08
HRP20220153T1 (hr) 2022-04-15
CN108138111B (zh) 2022-08-02
JP2022064917A (ja) 2022-04-26
US20180273885A1 (en) 2018-09-27
US11473042B2 (en) 2022-10-18
JP7338971B2 (ja) 2023-09-05
US20190367854A9 (en) 2019-12-05
EP3368652A1 (en) 2018-09-05
SI3368652T1 (sl) 2022-04-29

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