PL3364947T3 - Wodna kompozycja zawierająca dantrolen - Google Patents
Wodna kompozycja zawierająca dantrolenInfo
- Publication number
- PL3364947T3 PL3364947T3 PL16784877T PL16784877T PL3364947T3 PL 3364947 T3 PL3364947 T3 PL 3364947T3 PL 16784877 T PL16784877 T PL 16784877T PL 16784877 T PL16784877 T PL 16784877T PL 3364947 T3 PL3364947 T3 PL 3364947T3
- Authority
- PL
- Poland
- Prior art keywords
- dantrolene
- aqueous composition
- aqueous
- composition
- Prior art date
Links
- OZOMQRBLCMDCEG-CHHVJCJISA-N 1-[(z)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione Chemical compound C1=CC([N+](=O)[O-])=CC=C1C(O1)=CC=C1\C=N/N1C(=O)NC(=O)C1 OZOMQRBLCMDCEG-CHHVJCJISA-N 0.000 title 1
- 229960001987 dantrolene Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15190601 | 2015-10-20 | ||
EP16174999 | 2016-06-17 | ||
EP16784877.9A EP3364947B1 (en) | 2015-10-20 | 2016-10-19 | Aqueous composition comprising dantrolene |
PCT/EP2016/075086 WO2017067980A1 (en) | 2015-10-20 | 2016-10-19 | Aqueous composition comprising dantrolene |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3364947T3 true PL3364947T3 (pl) | 2022-02-07 |
Family
ID=57184442
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL16784877T PL3364947T3 (pl) | 2015-10-20 | 2016-10-19 | Wodna kompozycja zawierająca dantrolen |
Country Status (11)
Country | Link |
---|---|
US (2) | US11844782B2 (pl) |
EP (1) | EP3364947B1 (pl) |
JP (2) | JP7409772B2 (pl) |
KR (1) | KR102699155B1 (pl) |
CN (2) | CN118078742A (pl) |
CA (1) | CA3002113C (pl) |
ES (1) | ES2898425T3 (pl) |
MX (1) | MX2018004033A (pl) |
PL (1) | PL3364947T3 (pl) |
RU (1) | RU2729043C2 (pl) |
WO (1) | WO2017067980A1 (pl) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10532102B2 (en) * | 2016-08-19 | 2020-01-14 | Foresee Pharmaceuticals Co., Ltd. | Pharmaceutical composition and methods of uses |
EP3360539A1 (de) * | 2017-02-09 | 2018-08-15 | SapioTec GmbH | Pharmazeutische formulierung |
AU2018341136A1 (en) | 2017-09-27 | 2020-03-12 | Novartis Ag | Parenteral formulation comprising siponimod |
CN112770744A (zh) * | 2018-09-06 | 2021-05-07 | 希米科控股有限公司 | 丹曲洛林水性制剂及其制备方法 |
WO2021044608A1 (ja) * | 2019-09-06 | 2021-03-11 | シミックホールディングス株式会社 | ダントロレン水性製剤及びその調製方法 |
WO2022169582A1 (en) * | 2021-02-05 | 2022-08-11 | Uswm, Llc | Compositions and methods for clear concentrated parenteral delivery of dantrolene therapeutic agents |
EP4333806A1 (en) | 2021-05-06 | 2024-03-13 | Spepharm Ag | Pharmaceutical formulations |
WO2024184327A1 (en) * | 2023-03-03 | 2024-09-12 | Fastox Pharma Sa | Aqueous solutions of dantrolene |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5822011B2 (ja) | 1976-08-10 | 1983-05-06 | 山之内製薬株式会社 | 安定なダントロレンナトリウムの製剤 |
US6407079B1 (en) | 1985-07-03 | 2002-06-18 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation |
JPH06263636A (ja) * | 1993-03-12 | 1994-09-20 | Kiyoshi Kataoka | 脳または高次神経疾患治療剤 |
EP1084149A1 (en) | 1998-05-29 | 2001-03-21 | Janssen Pharmaceutica N.V. | Acylated alkylated cyclodextrin derivatives and their use as carriers for medicaments |
US7758890B2 (en) | 2001-06-23 | 2010-07-20 | Lyotropic Therapeutics, Inc. | Treatment using dantrolene |
JP2003321364A (ja) | 2002-05-07 | 2003-11-11 | Eisai Co Ltd | シクロデキストリンにより可溶化及び安定化された抗腫瘍剤含有組成物 |
JP2006199588A (ja) | 2003-05-06 | 2006-08-03 | Senju Pharmaceut Co Ltd | オキサゾリジノン誘導体含有水性液剤 |
JP4922762B2 (ja) * | 2004-08-10 | 2012-04-25 | 株式会社新日本科学 | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
WO2006134877A1 (ja) | 2005-06-13 | 2006-12-21 | Takeda Pharmaceutical Company Limited | 注射剤 |
ITMI20051999A1 (it) | 2005-10-21 | 2007-04-22 | Eratech S R L | Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita' |
KR100917809B1 (ko) | 2006-05-22 | 2009-09-18 | 에스케이케미칼주식회사 | 우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물 |
EP2583670A1 (en) | 2007-10-09 | 2013-04-24 | US Worldmeds LLC | Co-solvent compositions and methods for improved delivery of dantrolene therapeutic agents |
WO2009104080A2 (en) | 2008-02-20 | 2009-08-27 | Targia Pharmaceuticals | Cns pharmaceutical compositions and methods of use |
WO2010126818A1 (en) * | 2009-04-27 | 2010-11-04 | Usworldmeds Llc | Intranasal delivery system for dantrolene |
JP5320413B2 (ja) | 2011-01-18 | 2013-10-23 | 本田技研工業株式会社 | 自動変速機の制御装置 |
JP6263636B2 (ja) | 2014-01-13 | 2018-01-17 | 孫 松華Sun, Songhua | 錯化剤、その製造方法及び用途 |
-
2016
- 2016-10-19 KR KR1020187014238A patent/KR102699155B1/ko active IP Right Grant
- 2016-10-19 CN CN202410183630.0A patent/CN118078742A/zh active Pending
- 2016-10-19 MX MX2018004033A patent/MX2018004033A/es unknown
- 2016-10-19 CA CA3002113A patent/CA3002113C/en active Active
- 2016-10-19 ES ES16784877T patent/ES2898425T3/es active Active
- 2016-10-19 JP JP2018520391A patent/JP7409772B2/ja active Active
- 2016-10-19 PL PL16784877T patent/PL3364947T3/pl unknown
- 2016-10-19 WO PCT/EP2016/075086 patent/WO2017067980A1/en active Application Filing
- 2016-10-19 CN CN201680061801.6A patent/CN108366963A/zh active Pending
- 2016-10-19 RU RU2018117935A patent/RU2729043C2/ru active
- 2016-10-19 EP EP16784877.9A patent/EP3364947B1/en active Active
- 2016-10-19 US US15/952,477 patent/US11844782B2/en active Active
-
2023
- 2023-08-21 JP JP2023134091A patent/JP2023154096A/ja not_active Withdrawn
- 2023-11-07 US US18/503,401 patent/US20240091198A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP7409772B2 (ja) | 2024-01-09 |
CA3002113C (en) | 2024-05-28 |
US11844782B2 (en) | 2023-12-19 |
RU2018117935A3 (pl) | 2020-01-21 |
JP2018531268A (ja) | 2018-10-25 |
RU2729043C2 (ru) | 2020-08-04 |
KR102699155B1 (ko) | 2024-08-26 |
ES2898425T3 (es) | 2022-03-07 |
CN118078742A (zh) | 2024-05-28 |
EP3364947A1 (en) | 2018-08-29 |
EP3364947B1 (en) | 2021-09-15 |
US20180256548A1 (en) | 2018-09-13 |
CN108366963A (zh) | 2018-08-03 |
KR20180066239A (ko) | 2018-06-18 |
RU2018117935A (ru) | 2019-11-21 |
WO2017067980A1 (en) | 2017-04-27 |
CA3002113A1 (en) | 2017-04-27 |
US20240091198A1 (en) | 2024-03-21 |
MX2018004033A (es) | 2018-07-06 |
JP2023154096A (ja) | 2023-10-18 |
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