PL332242A1 - Tricyclic inhibitors of proteinous farnesil transferase - Google Patents
Tricyclic inhibitors of proteinous farnesil transferaseInfo
- Publication number
- PL332242A1 PL332242A1 PL97332242A PL33224297A PL332242A1 PL 332242 A1 PL332242 A1 PL 332242A1 PL 97332242 A PL97332242 A PL 97332242A PL 33224297 A PL33224297 A PL 33224297A PL 332242 A1 PL332242 A1 PL 332242A1
- Authority
- PL
- Poland
- Prior art keywords
- proteinous
- tricyclic inhibitors
- transferase
- farnesil
- compounds
- Prior art date
Links
- 102000004357 Transferases Human genes 0.000 title abstract 2
- 108090000992 Transferases Proteins 0.000 title abstract 2
- 229950008696 farnesil Drugs 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
- Cereal-Derived Products (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71332396A | 1996-09-13 | 1996-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL332242A1 true PL332242A1 (en) | 1999-08-30 |
Family
ID=24865689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL97332242A PL332242A1 (en) | 1996-09-13 | 1997-09-11 | Tricyclic inhibitors of proteinous farnesil transferase |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0929545B1 (OSRAM) |
| JP (1) | JP2001500510A (OSRAM) |
| KR (1) | KR20000036120A (OSRAM) |
| CN (1) | CN1104427C (OSRAM) |
| AT (1) | ATE286046T1 (OSRAM) |
| AU (1) | AU4337997A (OSRAM) |
| BR (1) | BR9712831A (OSRAM) |
| CA (1) | CA2266016C (OSRAM) |
| CZ (1) | CZ84399A3 (OSRAM) |
| DE (1) | DE69732120T2 (OSRAM) |
| ES (1) | ES2235252T3 (OSRAM) |
| HU (1) | HUP0000121A2 (OSRAM) |
| ID (1) | ID21699A (OSRAM) |
| IL (1) | IL128928A0 (OSRAM) |
| NO (1) | NO991234L (OSRAM) |
| NZ (1) | NZ334453A (OSRAM) |
| PL (1) | PL332242A1 (OSRAM) |
| SK (1) | SK33899A3 (OSRAM) |
| TR (1) | TR199901276T2 (OSRAM) |
| WO (1) | WO1998011093A1 (OSRAM) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3962B (en) | 1993-12-21 | 1996-05-27 | Albright & Wilson | Funcional fluids |
| US5939416A (en) * | 1997-06-17 | 1999-08-17 | Schering Corporation | Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors |
| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6433165B1 (en) | 1998-01-21 | 2002-08-13 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| WO1999037651A1 (en) | 1998-01-21 | 1999-07-29 | Millenium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6503926B2 (en) | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
| US8679096B2 (en) | 2007-06-21 | 2014-03-25 | Board Of Regents Of The University Of Nebraska | Multifunctional operational component for robotic devices |
| US9579088B2 (en) | 2007-02-20 | 2017-02-28 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices for surgical visualization and device manipulation |
| TW200902007A (en) * | 2007-05-25 | 2009-01-16 | Astrazeneca Ab | Spirocyclopropyl piperidine derivatives |
| JP5591696B2 (ja) | 2007-07-12 | 2014-09-17 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | 生検要素、アーム装置、および医療装置 |
| EP2178431A4 (en) | 2007-08-15 | 2017-01-18 | Board of Regents of the University of Nebraska | Medical inflation, attachment, and delivery devices and related methods |
| EP3714821A1 (en) | 2011-06-10 | 2020-09-30 | Board of Regents of the University of Nebraska | Surgical end effector |
| CA2841459C (en) | 2011-07-11 | 2020-07-28 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems, and related methods |
| EP3730031A1 (en) | 2011-10-03 | 2020-10-28 | Board of Regents of the University of Nebraska | Robotic surgical devices and systems |
| WO2013106569A2 (en) | 2012-01-10 | 2013-07-18 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices for surgical access and insertion |
| WO2014011238A2 (en) | 2012-05-01 | 2014-01-16 | Board Of Regents Of The University Of Nebraska | Single site robotic device and related systems and methods |
| EP3943255B1 (en) | 2012-06-22 | 2023-06-14 | Board of Regents of the University of Nebraska | Local control robotic surgical devices |
| US9770305B2 (en) | 2012-08-08 | 2017-09-26 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems, and related methods |
| WO2014025399A1 (en) | 2012-08-08 | 2014-02-13 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems, and related methods |
| US9888966B2 (en) | 2013-03-14 | 2018-02-13 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to force control surgical systems |
| CA2905948C (en) | 2013-03-14 | 2022-01-11 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to robotic surgical devices, end effectors, and controllers |
| CA2906772C (en) | 2013-03-15 | 2021-09-21 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems and related methods |
| US10966700B2 (en) | 2013-07-17 | 2021-04-06 | Virtual Incision Corporation | Robotic surgical devices, systems and related methods |
| WO2016040946A1 (en) | 2014-09-12 | 2016-03-17 | Board Of Regents Of University Of Nebraska | Quick-release end effectors and related systems and methods |
| EP4286104A3 (en) | 2014-11-11 | 2024-02-14 | Board of Regents of the University of Nebraska | Robotic device with compact joint design and related systems and methods |
| CN114027986B (zh) | 2015-08-03 | 2024-06-14 | 内布拉斯加大学董事会 | 机器人手术装置系统及相关方法 |
| JP7176757B2 (ja) | 2016-05-18 | 2022-11-22 | バーチャル インシジョン コーポレイション | ロボット手術装置、システム及び関連する方法 |
| EP3503829A4 (en) | 2016-08-25 | 2020-04-15 | Board of Regents of the University of Nebraska | Quick-release tool coupler and related systems and methods |
| EP3507065B1 (en) | 2016-08-30 | 2025-02-12 | Board of Regents of the University of Nebraska | Robotic device with compact joint design and an additional degree of freedom |
| EP3544539A4 (en) | 2016-11-22 | 2020-08-05 | Board of Regents of the University of Nebraska | ENHANCED COARSE POSITIONING DEVICE AND RELATED SYSTEMS AND PROCESSES |
| JP7099728B2 (ja) | 2016-11-29 | 2022-07-12 | バーチャル インシジョン コーポレイション | ユーザの存在検出機能を備えたユーザコントローラ、関連システムおよび方法 |
| WO2018112199A1 (en) | 2016-12-14 | 2018-06-21 | Virtual Incision Corporation | Releasable attachment device for coupling to medical devices and related systems and methods |
| JP7405432B2 (ja) | 2017-09-27 | 2023-12-26 | バーチャル インシジョン コーポレイション | 追跡カメラ技術を有するロボット手術デバイスならびに関連するシステムおよび方法 |
| WO2019136360A1 (en) | 2018-01-05 | 2019-07-11 | Board Of Regents Of The University Of Nebraska | Single-arm robotic device with compact joint design and related systems and methods |
| US11903658B2 (en) | 2019-01-07 | 2024-02-20 | Virtual Incision Corporation | Robotically assisted surgical system and related devices and methods |
| WO2022010887A1 (en) | 2020-07-06 | 2022-01-13 | Virtual Incision Corporation | Surgical Robot Positioning System and Related Devices and Methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| KR920014799A (ko) * | 1991-01-18 | 1992-08-25 | 나오가따 다이도 | 신규벤조[5,6]시클로헵타[1,2-b]피리딘 유도체 및 이를 함유하는 항알레르기제 |
| IL111257A0 (en) * | 1993-10-15 | 1994-12-29 | Schering Corp | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| AU699043B2 (en) * | 1993-10-15 | 1998-11-19 | Schering Corporation | Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
| TW350844B (en) * | 1995-12-22 | 1999-01-21 | Schering Corp | Tricyclic amides useful to inhibition of G-protein function and for treatment of proliferative diseases |
-
1997
- 1997-09-11 BR BR9712831-7A patent/BR9712831A/pt unknown
- 1997-09-11 AT AT97941480T patent/ATE286046T1/de not_active IP Right Cessation
- 1997-09-11 JP JP10513765A patent/JP2001500510A/ja not_active Ceased
- 1997-09-11 ES ES97941480T patent/ES2235252T3/es not_active Expired - Lifetime
- 1997-09-11 EP EP97941480A patent/EP0929545B1/en not_active Expired - Lifetime
- 1997-09-11 KR KR1019997002149A patent/KR20000036120A/ko not_active Withdrawn
- 1997-09-11 CN CN97199598A patent/CN1104427C/zh not_active Expired - Fee Related
- 1997-09-11 IL IL12892897A patent/IL128928A0/xx unknown
- 1997-09-11 HU HU0000121A patent/HUP0000121A2/hu unknown
- 1997-09-11 CA CA002266016A patent/CA2266016C/en not_active Expired - Fee Related
- 1997-09-11 NZ NZ334453A patent/NZ334453A/xx unknown
- 1997-09-11 DE DE69732120T patent/DE69732120T2/de not_active Expired - Fee Related
- 1997-09-11 SK SK338-99A patent/SK33899A3/sk unknown
- 1997-09-11 CZ CZ99843A patent/CZ84399A3/cs unknown
- 1997-09-11 WO PCT/US1997/015907 patent/WO1998011093A1/en not_active Ceased
- 1997-09-11 AU AU43379/97A patent/AU4337997A/en not_active Abandoned
- 1997-09-11 PL PL97332242A patent/PL332242A1/xx unknown
- 1997-09-11 TR TR1999/01276T patent/TR199901276T2/xx unknown
- 1997-11-09 ID IDW990086A patent/ID21699A/id unknown
-
1999
- 1999-03-12 NO NO991234A patent/NO991234L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ84399A3 (cs) | 1999-11-17 |
| NO991234L (no) | 1999-05-12 |
| BR9712831A (pt) | 1999-11-16 |
| WO1998011093A1 (en) | 1998-03-19 |
| NO991234D0 (no) | 1999-03-12 |
| IL128928A0 (en) | 2000-02-17 |
| DE69732120D1 (de) | 2005-02-03 |
| ATE286046T1 (de) | 2005-01-15 |
| CA2266016A1 (en) | 1998-03-19 |
| NZ334453A (en) | 2000-08-25 |
| ES2235252T3 (es) | 2005-07-01 |
| EP0929545A1 (en) | 1999-07-21 |
| CN1237165A (zh) | 1999-12-01 |
| JP2001500510A (ja) | 2001-01-16 |
| CA2266016C (en) | 2004-06-01 |
| AU4337997A (en) | 1998-04-02 |
| HUP0000121A2 (hu) | 2001-04-28 |
| TR199901276T2 (xx) | 1999-09-21 |
| DE69732120T2 (de) | 2005-12-08 |
| SK33899A3 (en) | 2000-02-14 |
| KR20000036120A (ko) | 2000-06-26 |
| ID21699A (id) | 1999-07-15 |
| CN1104427C (zh) | 2003-04-02 |
| EP0929545B1 (en) | 2004-12-29 |
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