PL3277083T3 - Zastosowanie kompozycji do prezerwacji narządów w celu prezerwacji narządu lub jego części - Google Patents

Zastosowanie kompozycji do prezerwacji narządów w celu prezerwacji narządu lub jego części

Info

Publication number
PL3277083T3
PL3277083T3 PL16727247.5T PL16727247T PL3277083T3 PL 3277083 T3 PL3277083 T3 PL 3277083T3 PL 16727247 T PL16727247 T PL 16727247T PL 3277083 T3 PL3277083 T3 PL 3277083T3
Authority
PL
Poland
Prior art keywords
organ
preserving
parts
preservation compositions
compositions
Prior art date
Application number
PL16727247.5T
Other languages
English (en)
Inventor
Benedict Marie Doorschodt
Original Assignee
Vivalyx Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vivalyx Gmbh filed Critical Vivalyx Gmbh
Publication of PL3277083T3 publication Critical patent/PL3277083T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/30Alkali metal phosphates
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01DCOMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, POTASSIUM, RUBIDIUM, CAESIUM, OR FRANCIUM
    • C01D7/00Carbonates of sodium, potassium or alkali metals in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/10Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/08Polyethers derived from hydroxy compounds or from their metallic derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Physiology (AREA)
PL16727247.5T 2015-04-03 2016-04-01 Zastosowanie kompozycji do prezerwacji narządów w celu prezerwacji narządu lub jego części PL3277083T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2014584 2015-04-03
PCT/NL2016/050228 WO2016159773A1 (en) 2015-04-03 2016-04-01 Organ preservation composition

Publications (1)

Publication Number Publication Date
PL3277083T3 true PL3277083T3 (pl) 2025-05-26

Family

ID=56101775

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16727247.5T PL3277083T3 (pl) 2015-04-03 2016-04-01 Zastosowanie kompozycji do prezerwacji narządów w celu prezerwacji narządu lub jego części

Country Status (6)

Country Link
US (1) US10874098B2 (pl)
EP (1) EP3277083B1 (pl)
CA (1) CA2981588A1 (pl)
ES (1) ES3010496T3 (pl)
PL (1) PL3277083T3 (pl)
WO (1) WO2016159773A1 (pl)

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* Cited by examiner, † Cited by third party
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MX2021001205A (es) * 2018-07-30 2021-09-08 Acorn Biolabs Inc Composiciones para transporte y/o crioconservación de células y/o tejidos.
CN110352951A (zh) * 2018-11-15 2019-10-22 崔磊 一种无血清无dmso组织工程骨冻存液及其制备和冻存方法
CN109438555B (zh) * 2018-11-22 2022-07-29 浙江海洋大学 一种非天然抗氧化肽的制备方法
IT201900007446A1 (it) 2019-05-29 2020-11-29 Giuseppe Castellano Composizione comprendente citrato e carnitina in grado di attivare la produzione della proteina klotho
CN112167240A (zh) * 2019-07-02 2021-01-05 南京三生生物技术股份有限公司 临床级细胞冷藏保存液及其制备方法和应用
WO2021198865A1 (en) * 2020-03-28 2021-10-07 University Health Network Methods, compositions, and systems for enhancing ex-vivo organ perfusion
EP4338590A4 (en) * 2021-05-11 2025-04-30 Bmg Incorporated COLD STORAGE SOLUTION AND STORAGE METHOD FOR STEM CELLS
CA3220730A1 (en) * 2021-05-31 2022-12-08 Mingyao Liu Compositions and methods for lung preservation
CN114052008A (zh) * 2021-11-23 2022-02-18 中山大学附属第三医院(中山大学肝脏病医院) 一种保存液及其应用
WO2023201038A1 (en) * 2022-04-15 2023-10-19 Marizyme, Inc. Powder formulations and use thereof in medical and/or surgical procedures
CN115349514B (zh) * 2022-07-08 2024-02-27 杭州联川生物技术股份有限公司 一种新鲜组织冻存液及其制备方法和应用
EP4627054A1 (en) * 2022-12-01 2025-10-08 The Cleveland Clinic Foundation Perfusate compositions, methods, and systems
CN116459342A (zh) * 2023-03-27 2023-07-21 中国人民解放军总医院海南医院 一种用于急性心肌梗死闭塞血管远端的溶栓组合物
WO2024211696A1 (en) 2023-04-07 2024-10-10 Biogen Ma Inc. 1h-pyrrolo[2,3-b]pyridin-4-yl]-2-oxopyrrolidine-3-carbonitrile derivatives as tyrosine kinase 2 (tyk2) inhibitors for the treatment of inflammatory diseases
US20250049842A1 (en) * 2023-07-13 2025-02-13 James D. Ervin Therapeutic blood-acid-shifting compositions and methods
WO2025247851A1 (en) * 2024-05-27 2025-12-04 Artidis Ag Preservation reagents for biological samples and use thereof

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SE8105887L (sv) 1981-10-06 1983-04-07 Erland Johansson Blandning for human tillforsel av selen som sparemne
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US4879283A (en) 1985-10-03 1989-11-07 Wisconsin Alumni Research Foundation Solution for the preservation of organs
US4923442A (en) 1988-05-02 1990-05-08 Cryomedical Sciences Inc. Blood substitute
US4920044A (en) 1988-11-08 1990-04-24 The Cleveland Clinic Foundation Intracellular flush solution for preserving organs
US4938961A (en) 1989-04-28 1990-07-03 Geoffrey Collins Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia
US5182299A (en) 1990-03-19 1993-01-26 Brigham And Women's Hospital Treatment of osmotic disturbance with organic osmolytes
WO1991014435A1 (en) * 1990-03-19 1991-10-03 Brigham And Women's Hospital Treatment of osmotic disturbance with organic osmolytes
US5599659A (en) 1993-03-11 1997-02-04 Breonics, Inc. Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
US6153582A (en) 1998-11-05 2000-11-28 Bausch & Lomb Surgical, Inc. Defined serumfree medical solution for ophthalmology
FR2785501B1 (fr) 1998-11-10 2001-01-05 Centre Nat Rech Scient Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
WO2000032140A1 (en) 1998-11-30 2000-06-08 Ivf Sciences Colorado, Inc. System and sequential culture media for in vitro fertilization
FR2793651B1 (fr) 1999-05-18 2003-05-16 Cair L G L Solution aqueuse de conservation de tissus et d'organes
US6492103B1 (en) * 2000-01-31 2002-12-10 Organ Recovery Systems, Inc. System for organ and tissue preservation and hypothermic blood substitution
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US8637230B2 (en) * 2004-11-12 2014-01-28 Organoflush B.V. Composition for cold preservation and perfusion of organs
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Also Published As

Publication number Publication date
US10874098B2 (en) 2020-12-29
CA2981588A1 (en) 2016-10-06
EP3277083C0 (en) 2025-01-22
ES3010496T3 (en) 2025-04-03
EP3277083B1 (en) 2025-01-22
EP3277083A1 (en) 2018-02-07
WO2016159773A1 (en) 2016-10-06
US20180070582A1 (en) 2018-03-15

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