PL324688A1 - Human endoglin gene promotor, nucleic acid construct, cell containing such construct, application of such construct in production of a pharmaceutic agent, method of obtaining such pharmaceutic agent and pharmaceutic agent obtained thereby - Google Patents

Human endoglin gene promotor, nucleic acid construct, cell containing such construct, application of such construct in production of a pharmaceutic agent, method of obtaining such pharmaceutic agent and pharmaceutic agent obtained thereby

Info

Publication number
PL324688A1
PL324688A1 PL98324688A PL32468898A PL324688A1 PL 324688 A1 PL324688 A1 PL 324688A1 PL 98324688 A PL98324688 A PL 98324688A PL 32468898 A PL32468898 A PL 32468898A PL 324688 A1 PL324688 A1 PL 324688A1
Authority
PL
Poland
Prior art keywords
construct
pharmaceutic agent
pharmaceutic
obtaining
nucleic acid
Prior art date
Application number
PL98324688A
Other languages
English (en)
Inventor
Wolff Graulich
Dirk Nettelbeck
Hans-Harald Sedlacek
Rolf Mueller
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PL324688A1 publication Critical patent/PL324688A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
PL98324688A 1997-02-06 1998-02-06 Human endoglin gene promotor, nucleic acid construct, cell containing such construct, application of such construct in production of a pharmaceutic agent, method of obtaining such pharmaceutic agent and pharmaceutic agent obtained thereby PL324688A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19704301A DE19704301C1 (de) 1997-02-06 1997-02-06 Der Promotor des humanen Endoglingens und seine Verwendung für die Gentherapie

Publications (1)

Publication Number Publication Date
PL324688A1 true PL324688A1 (en) 1998-08-17

Family

ID=7819364

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98324688A PL324688A1 (en) 1997-02-06 1998-02-06 Human endoglin gene promotor, nucleic acid construct, cell containing such construct, application of such construct in production of a pharmaceutic agent, method of obtaining such pharmaceutic agent and pharmaceutic agent obtained thereby

Country Status (15)

Country Link
US (1) US6103527A (enExample)
EP (1) EP0857781A3 (enExample)
JP (1) JPH11178A (enExample)
KR (1) KR19980071084A (enExample)
CN (1) CN1196784C (enExample)
AR (1) AR011110A1 (enExample)
AU (1) AU736724B2 (enExample)
BR (1) BR9800563A (enExample)
CA (1) CA2222981A1 (enExample)
CZ (1) CZ289227B6 (enExample)
DE (1) DE19704301C1 (enExample)
HU (1) HUP9800247A3 (enExample)
PL (1) PL324688A1 (enExample)
RU (1) RU2230115C2 (enExample)
TR (1) TR199800168A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19704301C1 (de) * 1997-02-06 1998-03-26 Hoechst Ag Der Promotor des humanen Endoglingens und seine Verwendung für die Gentherapie
CZ121599A3 (cs) 1998-04-09 1999-10-13 Aventis Pharma Deutschland Gmbh Jednořetězcová molekula vázající několik antigenů, způsob její přípravy a léčivo obsahující tuto molekulu
DE60013586T2 (de) 1999-04-02 2005-02-03 Hisamitsu Pharmaceutical Co., Inc., Tosu Genexpressions-basensequenzen zur therapeutischen anwendung und heilmittel zur gentherapie
RU2295281C2 (ru) * 2005-04-20 2007-03-20 Федеральное государственное учреждение Научно-исследовательский институт детских инфекций, г.Санкт-Петербург Способ оценки тяжести инфекционного поражения цнс у детей
RU2297848C2 (ru) * 2005-05-11 2007-04-27 Александр Веньяминович Иткес Генно-инженерная конструкция vegf-ибмед (vegf-ibmed)
WO2009045370A2 (en) 2007-09-28 2009-04-09 Intrexon Corporation Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
US20110172293A1 (en) 2008-07-08 2011-07-14 Fish Jason E Methods and Compositions for Modulating Angiogenesis
WO2014123749A1 (en) 2013-01-30 2014-08-14 Board Of Regents Of The University Of Nebraska Compositions and methods for treating complications associated with diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466596A (en) * 1992-08-25 1995-11-14 Mount Sinai Hospital Corporation Tissue specific transcriptional regulatory element
GB9506466D0 (en) * 1994-08-26 1995-05-17 Prolifix Ltd Cell cycle regulated repressor and dna element
DE19704301C1 (de) * 1997-02-06 1998-03-26 Hoechst Ag Der Promotor des humanen Endoglingens und seine Verwendung für die Gentherapie

Also Published As

Publication number Publication date
AU736724B2 (en) 2001-08-02
BR9800563A (pt) 1999-06-29
CN1196784C (zh) 2005-04-13
HUP9800247A2 (hu) 1998-10-28
CA2222981A1 (en) 1998-08-06
RU2230115C2 (ru) 2004-06-10
EP0857781A3 (de) 2001-05-16
CZ289227B6 (cs) 2001-12-12
HUP9800247A3 (en) 2002-11-28
CN1203948A (zh) 1999-01-06
JPH11178A (ja) 1999-01-06
MX9800981A (es) 1998-08-30
CZ33298A3 (cs) 1998-08-12
HU9800247D0 (en) 1998-03-30
DE19704301C1 (de) 1998-03-26
AR011110A1 (es) 2000-08-02
KR19980071084A (ko) 1998-10-26
EP0857781A2 (de) 1998-08-12
TR199800168A2 (xx) 1998-08-21
AU5293198A (en) 1998-08-13
US6103527A (en) 2000-08-15

Similar Documents

Publication Publication Date Title
PL324328A1 (en) Novel nucleic acid construct, method of obtaining same, application thereof, method of manufacturing a pharmaceutic agent, method of producing cells, method of producing protein and pharmaceutic agent as such
PL323657A1 (en) Novel nucleic acid construct, vector containing such construct, pharmaceutic agent, cell containing said construct, method of obtaining same, application thereof and methid if obtaining a pharmaceutic agent
PL326509A1 (en) Derivatives of phenylacetic acid, method of and intermediate products used in obtaining them and agents containing such derivatives
CZ200151A3 (en) Sulfur-substituted N-arylamides of sulfonylaminocarboxylic acid, process of their preparation, their use and pharmaceutical preparations in which they are comprised
PL329042A1 (en) Novel derivatives of pyrazole, method of obtaining them, pharmaceutic agent, application of such derivatives in production of a pharmaceutic agent and method of obtaining such pharmaceutic agent
PL325363A1 (en) Novel 1,4-benzothiazepin 1,1-dioxides, method of obtaining them, pharmaceutic agent, therapeutic process employing them and their application in production of a pharmaceutic agent
PL347125A1 (en) Methods of nucleic acid amplification and sequencing
PL340364A1 (en) Nucleic acid molecules encoding proteins exhibiting activity of fructosiltransferase and methods of obtaining long-chain inulin
PL331863A1 (en) 7alpha-(xi-aminoalkyl)-estrathienes, method of obtaining them, pharmacautic preparations containing such compounds and their application in production of therapeutic agents
PL329790A1 (en) Novel derivatives of imidazolidine, method of obtaining such derivatives, their application in production of a pharmaceutic agent, pharmaceutic agent as such and method of obtaining a pharmaceutic agent
HUT47972A (en) Halogen-aryl-nitriles degrading gene, process for its application and cells comprising same
ZA864525B (en) Vector for expression of interferon-ypsilon in mammalian cells,method for using it and product obtained
PL330452A1 (en) Nucleic acid construct, isolated cell, application of such nucleic acid construct and method of obtaining same, application of such isolated cell, method of obtaining a pharmaceutic agent and pharmaceutic agent as such
GB9718196D0 (en) Nucleic Acid Sequencing Gels
PL303915A1 (en) Nucleic acid, recombination expressive construct, eucariotic cell, method of screening antiosteoporosis agents and pharmaceutical agent
NZ291554A (en) Production of soluble polymer-linked peptide/nucleic acid libraries
PL324549A1 (en) Novel derivatives of isoxazole and crotonic acid, method of obtaining them, pharmaceutic agent and application of such derivatives in production of pharmaceutic agents
AU6855796A (en) In vivo electroporation of cells
AU7672296A (en) Method of preparing electrochemical cells
PL328686A1 (en) Novel derivatives of imidazollydine, method of obtaining them, their application in production of pharmaceutic agents and pharmaceutic agent as such
PL324688A1 (en) Human endoglin gene promotor, nucleic acid construct, cell containing such construct, application of such construct in production of a pharmaceutic agent, method of obtaining such pharmaceutic agent and pharmaceutic agent obtained thereby
PL328762A1 (en) Novel biphenylsulphocyanamides, method of obtaining them, their application in production of pharmaceutic agents and pharmaceutic agent as such
IL130886A0 (en) Nucleic acid sequencing
PL306730A1 (en) Derivatives of alpha-pyrimidinylacrylic acid, method of obtaining them and their applications
AU8597598A (en) Stable encapsulated reference nucleic acid and method of making