PL3133396T3 - Sposób leczenia z zastosowaniem leków wychwytujących amoniak - Google Patents

Sposób leczenia z zastosowaniem leków wychwytujących amoniak

Info

Publication number
PL3133396T3
PL3133396T3 PL16176456T PL16176456T PL3133396T3 PL 3133396 T3 PL3133396 T3 PL 3133396T3 PL 16176456 T PL16176456 T PL 16176456T PL 16176456 T PL16176456 T PL 16176456T PL 3133396 T3 PL3133396 T3 PL 3133396T3
Authority
PL
Poland
Prior art keywords
drugs
ammonia
treatment
Prior art date
Application number
PL16176456T
Other languages
English (en)
Inventor
Bruce Scharschmidt
Original Assignee
Horizon Therapeutics, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41255339&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3133396(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Horizon Therapeutics, Llc filed Critical Horizon Therapeutics, Llc
Publication of PL3133396T3 publication Critical patent/PL3133396T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL16176456T 2008-04-29 2009-01-07 Sposób leczenia z zastosowaniem leków wychwytujących amoniak PL3133396T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4883008P 2008-04-29 2008-04-29
US9323408P 2008-08-29 2008-08-29
EP09739263.3A EP2330892B1 (en) 2008-04-29 2009-01-07 Methods of treatment using ammonia-scavenging drugs
EP16176456.8A EP3133396B1 (en) 2008-04-29 2009-01-07 Methods of treatment using ammonia-scavenging drugs
PCT/US2009/030362 WO2009134460A1 (en) 2008-04-29 2009-01-07 Methods of treatment using ammonia-scavenging drugs

Publications (1)

Publication Number Publication Date
PL3133396T3 true PL3133396T3 (pl) 2019-03-29

Family

ID=41255339

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16176456T PL3133396T3 (pl) 2008-04-29 2009-01-07 Sposób leczenia z zastosowaniem leków wychwytujących amoniak

Country Status (12)

Country Link
US (2) US8642012B2 (pl)
EP (2) EP2330892B1 (pl)
CA (1) CA2735218A1 (pl)
CY (3) CY1118543T1 (pl)
DK (1) DK2330892T3 (pl)
GB (1) GB2470310A (pl)
HU (1) HUS1600057I1 (pl)
LT (1) LTC2330892I2 (pl)
NL (1) NL300854I2 (pl)
NO (1) NO2016023I2 (pl)
PL (1) PL3133396T3 (pl)
WO (1) WO2009134460A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3133396T3 (pl) 2008-04-29 2019-03-29 Horizon Therapeutics, Llc Sposób leczenia z zastosowaniem leków wychwytujących amoniak
PT2456304E (pt) 2009-07-24 2015-10-12 Baylor College Medicine Métodos de modulação de ácidos de cadeia ramificada e utilização dos mesmos
AU2012316750B2 (en) 2011-09-30 2017-08-31 Immedica Pharma Ab Methods of therapeutic monitoring of nitrogen scavenging drugs
CN111991383A (zh) * 2012-04-20 2020-11-27 伊梅尔迪卡制药公司 苯乙酸前药的治疗性监测方法
HK1210699A1 (en) 2012-11-21 2016-05-06 Horizon Therapeutics, Inc. Methods of administering and evaluating nitrogen scavenging drugs for the treatment of hepatic encephalopathy
HRP20191710T1 (hr) 2013-10-14 2019-12-13 Immedica Pharma Ab Postupci za liječenje poremećaja ciklusa uree
US20160243071A1 (en) 2013-11-14 2016-08-25 John KLOPP Solid compositions of triglycerides and uses thereof
AU2015253100B2 (en) 2014-04-30 2018-01-18 The Johns Hopkins University Dendrimer compositions and their use in treatment of diseases of the eye
WO2015187641A1 (en) * 2014-06-04 2015-12-10 Horizon Therapeutics, Inc. Methods for treating urea cycle disorders to prevent hyperammonemic crises by controlling blood ammonia levels
CA2957721C (en) 2014-08-13 2021-04-13 The Johns Hopkins University Selective dendrimer delivery to brain tumors
CA3003589C (en) 2015-10-29 2021-12-07 The Johns Hopkins University Dendrimer compositions and methods for treatment of peroxisomal disorders and leukodystrophies
US9914692B2 (en) 2016-05-25 2018-03-13 Horizon Therapeutics, Llc Procedure for the preparation of 4-phenyl butyrate and uses thereof
WO2018170234A1 (en) 2017-03-15 2018-09-20 President And Fellows Of Harvard College Methods and compositions for treating cancer
EP4119133A1 (en) * 2017-05-24 2023-01-18 Thoeris GmbH Glutamine synthetase protein conjugate
WO2019006164A1 (en) 2017-06-28 2019-01-03 Baylor College Of Medicine POLYTHERAPY TO TREAT UREA CYCLE DISORDERS
US10668040B2 (en) 2017-09-11 2020-06-02 Horizon Therapeutics, Llc Treatment of urea cycle disorders in neonates and infants
US12465212B2 (en) 2019-03-28 2025-11-11 Zoll Medical Corporation Systems and methods for providing drug prescription information with monitored cardiac information
EP4069308A2 (en) 2019-12-04 2022-10-12 Ashvattha Therapeutics, Inc. Dendrimer compositions and methods for drug delivery to the eye

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284647A (en) * 1980-03-31 1981-08-18 The Johns Hopkins University Process for waste nitrogen removal
CA2212047C (en) * 1995-02-07 2010-11-16 Saul W. Brusilow Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in treatment of various disorders
DE19805854C1 (de) * 1998-02-13 1999-05-12 Claas Usines France Schalteinrichtung für Schneidmesser
US6219567B1 (en) * 1999-06-21 2001-04-17 Cardiox Corporation Monitoring of total ammoniacal concentration in blood
US20040229948A1 (en) * 2002-04-12 2004-11-18 Summar Marshall L. Method for preventing hepatic encephalopathic episodes
ES2341120T3 (es) 2004-11-26 2010-06-15 Ucl Business Plc Composiciones que comprenden ornitina y fenilacetato o fenilbutirato para tratar encefalopatia hepatica.
US20060135612A1 (en) * 2004-12-17 2006-06-22 U.S. Department Of Veterans Affairs Method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as amyotrophic lateral sclerosis (ALS), by using a HDAC inhibiting agent
JP5468015B2 (ja) 2008-01-08 2014-04-09 アクセリア ファーマシューティカルズ 抗菌ペプチド系に対する作動薬
PL3133396T3 (pl) 2008-04-29 2019-03-29 Horizon Therapeutics, Llc Sposób leczenia z zastosowaniem leków wychwytujących amoniak
WO2010025303A1 (en) 2008-08-29 2010-03-04 Hyperion Therapeutics Dosing and monitoring patients on nitrogen-scavenging drugs

Also Published As

Publication number Publication date
EP3133396B1 (en) 2018-09-05
CY2016053I1 (el) 2017-06-28
EP2330892B1 (en) 2016-06-29
EP2330892A1 (en) 2011-06-15
EP3133396A1 (en) 2017-02-22
GB201013468D0 (en) 2010-09-22
NO2016023I2 (no) 2016-12-27
DK2330892T3 (en) 2016-08-22
HUS1600057I1 (hu) 2017-01-30
US20140256807A1 (en) 2014-09-11
CA2735218A1 (en) 2009-11-05
NL300854I2 (pl) 2017-02-02
LTPA2016041I1 (lt) 2017-01-10
NO2016023I1 (no) 2016-12-14
CY1121288T1 (el) 2020-05-29
WO2009134460A1 (en) 2009-11-05
US20100008859A1 (en) 2010-01-14
CY1118543T1 (el) 2017-06-28
EP2330892A4 (en) 2012-01-11
LTC2330892I2 (lt) 2018-06-11
US8642012B2 (en) 2014-02-04
CY2016053I2 (el) 2017-06-28
GB2470310A (en) 2010-11-17

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