PL2986325T3 - Sposoby leczenia zaburzenia cyklu mocznikowego - Google Patents
Sposoby leczenia zaburzenia cyklu mocznikowegoInfo
- Publication number
- PL2986325T3 PL2986325T3 PL14854074T PL14854074T PL2986325T3 PL 2986325 T3 PL2986325 T3 PL 2986325T3 PL 14854074 T PL14854074 T PL 14854074T PL 14854074 T PL14854074 T PL 14854074T PL 2986325 T3 PL2986325 T3 PL 2986325T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- urea cycle
- cycle disorder
- treating urea
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7057—(Intracellular) signaling and trafficking pathways
- G01N2800/7066—Metabolic pathways
- G01N2800/708—Nitrogen metabolism, e.g. urea cycle
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361890827P | 2013-10-14 | 2013-10-14 | |
| US201462044168P | 2014-08-29 | 2014-08-29 | |
| PCT/US2014/060543 WO2015057747A1 (en) | 2013-10-14 | 2014-10-14 | Methods of treating urea cycle disorders |
| EP14854074.3A EP2986325B1 (en) | 2013-10-14 | 2014-10-14 | Methods of treating urea cycle disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2986325T3 true PL2986325T3 (pl) | 2020-03-31 |
Family
ID=52810198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14854074T PL2986325T3 (pl) | 2013-10-14 | 2014-10-14 | Sposoby leczenia zaburzenia cyklu mocznikowego |
Country Status (14)
| Country | Link |
|---|---|
| US (7) | US20150105469A1 (pl) |
| EP (1) | EP2986325B1 (pl) |
| CY (1) | CY1122220T1 (pl) |
| DK (1) | DK2986325T3 (pl) |
| ES (1) | ES2746999T3 (pl) |
| HR (1) | HRP20191710T1 (pl) |
| HU (1) | HUE045106T2 (pl) |
| LT (1) | LT2986325T (pl) |
| PL (1) | PL2986325T3 (pl) |
| PT (1) | PT2986325T (pl) |
| RS (1) | RS59429B1 (pl) |
| SI (1) | SI2986325T1 (pl) |
| SM (1) | SMT201900542T1 (pl) |
| WO (1) | WO2015057747A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3263102A1 (en) | 2011-09-30 | 2018-01-03 | Horizon Therapeutics, LLC | Methods of therapeutic monitoring of nitrogen scavenging drugs |
| HUE036133T2 (hu) | 2012-11-21 | 2018-06-28 | Horizon Therapeutics Llc | Eljárások hepatikus enkefalopátia kezelésére szolgáló nitrogénelvonó gyógyszerek beadására és értékelésére |
| WO2017147193A1 (en) * | 2016-02-22 | 2017-08-31 | Horizon Therapeutics, Llc | Treatment of urea cycle disorders in neonates and infants |
| US9914692B2 (en) | 2016-05-25 | 2018-03-13 | Horizon Therapeutics, Llc | Procedure for the preparation of 4-phenyl butyrate and uses thereof |
| US10668040B2 (en) | 2017-09-11 | 2020-06-02 | Horizon Therapeutics, Llc | Treatment of urea cycle disorders in neonates and infants |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996024571A1 (en) | 1995-02-07 | 1996-08-15 | Brusilow Saul W | Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in treatment of various disorders |
| GB2465250B (en) * | 2008-08-29 | 2011-01-26 | Ucyclyd Pharma Inc | Dosing and monitoring patients on nitrogen-scavenging drugs |
| WO2009134460A1 (en) | 2008-04-29 | 2009-11-05 | Hyperion Therapeutics | Methods of treatment using ammonia-scavenging drugs |
| EP2954780A1 (en) * | 2009-07-24 | 2015-12-16 | Baylor College Of Medicine | Methods of modulation of branched chain acids and uses thereof |
| EP3263102A1 (en) | 2011-09-30 | 2018-01-03 | Horizon Therapeutics, LLC | Methods of therapeutic monitoring of nitrogen scavenging drugs |
| BR112014026138A2 (pt) | 2012-04-20 | 2017-06-27 | Hyperion Therapeutics Inc | métodos de monitoramento terapêutico de pró-fármacos de ácido fenilacético |
-
2014
- 2014-10-14 PL PL14854074T patent/PL2986325T3/pl unknown
- 2014-10-14 SM SM20190542T patent/SMT201900542T1/it unknown
- 2014-10-14 SI SI201431340T patent/SI2986325T1/sl unknown
- 2014-10-14 ES ES14854074T patent/ES2746999T3/es active Active
- 2014-10-14 RS RSP20191147 patent/RS59429B1/sr unknown
- 2014-10-14 WO PCT/US2014/060543 patent/WO2015057747A1/en not_active Ceased
- 2014-10-14 LT LTEP14854074.3T patent/LT2986325T/lt unknown
- 2014-10-14 HU HUE14854074A patent/HUE045106T2/hu unknown
- 2014-10-14 EP EP14854074.3A patent/EP2986325B1/en active Active
- 2014-10-14 DK DK14854074.3T patent/DK2986325T3/da active
- 2014-10-14 PT PT148540743T patent/PT2986325T/pt unknown
- 2014-10-14 HR HRP20191710 patent/HRP20191710T1/hr unknown
- 2014-10-14 US US14/514,334 patent/US20150105469A1/en not_active Abandoned
-
2015
- 2015-11-12 US US14/939,127 patent/US20160074356A1/en not_active Abandoned
-
2017
- 2017-06-30 US US15/639,171 patent/US20170354631A1/en not_active Abandoned
- 2017-08-25 US US15/687,144 patent/US20180015065A1/en not_active Abandoned
- 2017-08-25 US US15/687,141 patent/US20170354632A1/en not_active Abandoned
- 2017-09-08 US US15/699,188 patent/US20180021292A1/en not_active Abandoned
-
2019
- 2019-09-16 CY CY20191100964T patent/CY1122220T1/el unknown
-
2020
- 2020-03-06 US US16/811,861 patent/US20200405678A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20180021292A1 (en) | 2018-01-25 |
| US20170354631A1 (en) | 2017-12-14 |
| RS59429B1 (sr) | 2019-11-29 |
| WO2015057747A1 (en) | 2015-04-23 |
| HK1219656A1 (en) | 2017-04-13 |
| EP2986325B1 (en) | 2019-06-26 |
| PT2986325T (pt) | 2019-10-09 |
| EP2986325A4 (en) | 2016-07-27 |
| CY1122220T1 (el) | 2020-11-25 |
| DK2986325T3 (da) | 2019-09-23 |
| US20180015065A1 (en) | 2018-01-18 |
| US20170354632A1 (en) | 2017-12-14 |
| ES2746999T3 (es) | 2020-03-09 |
| HUE045106T2 (hu) | 2019-12-30 |
| US20150105469A1 (en) | 2015-04-16 |
| EP2986325A1 (en) | 2016-02-24 |
| HRP20191710T1 (hr) | 2019-12-13 |
| SI2986325T1 (sl) | 2020-02-28 |
| LT2986325T (lt) | 2019-10-10 |
| SMT201900542T1 (it) | 2019-11-13 |
| US20200405678A1 (en) | 2020-12-31 |
| US20160074356A1 (en) | 2016-03-17 |
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