PL294457A2 - Method of obtaining novel 3-(indolocarbonamide-2)-quinuclidines - Google Patents

Method of obtaining novel 3-(indolocarbonamide-2)-quinuclidines

Info

Publication number
PL294457A2
PL294457A2 PL29445792A PL29445792A PL294457A2 PL 294457 A2 PL294457 A2 PL 294457A2 PL 29445792 A PL29445792 A PL 29445792A PL 29445792 A PL29445792 A PL 29445792A PL 294457 A2 PL294457 A2 PL 294457A2
Authority
PL
Poland
Prior art keywords
indolocarbonamide
quinuclidines
obtaining novel
novel
obtaining
Prior art date
Application number
PL29445792A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL294457A2 publication Critical patent/PL294457A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL29445792A 1991-05-10 1992-05-07 Method of obtaining novel 3-(indolocarbonamide-2)-quinuclidines PL294457A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4115215A DE4115215A1 (de) 1991-05-10 1991-05-10 Indolderivate

Publications (1)

Publication Number Publication Date
PL294457A2 true PL294457A2 (en) 1992-11-16

Family

ID=6431344

Family Applications (1)

Application Number Title Priority Date Filing Date
PL29445792A PL294457A2 (en) 1991-05-10 1992-05-07 Method of obtaining novel 3-(indolocarbonamide-2)-quinuclidines

Country Status (14)

Country Link
EP (1) EP0512350A3 (enExample)
JP (1) JPH05155886A (enExample)
KR (1) KR920021507A (enExample)
AU (1) AU1604492A (enExample)
CA (1) CA2068238A1 (enExample)
CS (1) CS130592A3 (enExample)
DE (1) DE4115215A1 (enExample)
HU (1) HU208136B (enExample)
IE (1) IE921488A1 (enExample)
MX (1) MX9202152A (enExample)
NO (1) NO921831L (enExample)
PL (1) PL294457A2 (enExample)
TW (1) TW221807B (enExample)
ZA (1) ZA923351B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8405891A (en) * 1990-08-31 1992-03-30 Nippon Shinyaku Co. Ltd. Indole derivative and medicine
IT1255467B (it) * 1992-07-29 1995-11-02 Dompe Farmaceutici Spa Ammidi acriliche farmacologicamente attive
US6486172B2 (en) 2000-08-18 2002-11-26 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
EP1381603A2 (en) 2000-08-18 2004-01-21 PHARMACIA & UPJOHN COMPANY Quinuclidine-substituedaryl moieties for treatment of disease ( nicotinic acetylcholine receptor ligands )
US6492385B2 (en) 2000-08-18 2002-12-10 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6599916B2 (en) 2000-08-21 2003-07-29 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
AU2001282875A1 (en) 2000-08-21 2002-03-04 Pharmacia And Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
DE10045112A1 (de) * 2000-09-11 2002-03-21 Merck Patent Gmbh Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
KR100614900B1 (ko) 2001-10-02 2006-08-25 파마시아 앤드 업존 캄파니 엘엘씨 질병의 치료를 위한 아자비시클릭-치환된 융합-헤테로아릴화합물
US6849620B2 (en) 2001-10-26 2005-02-01 Pfizer Inc N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
DE10164139A1 (de) * 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
MXPA04008152A (es) 2002-02-19 2005-09-08 Upjohn Co Compuestos azabiciclicos para el tratamiento de enfermedades.
JP2005523288A (ja) 2002-02-19 2005-08-04 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 疾病治療用の縮合した二環式−n−架橋−複素環式芳香族カルボキサミド
JP2005537297A (ja) 2002-08-01 2005-12-08 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー アルファ−7nachr活性を有する1h−ピラゾールおよび1h−ピロール−アザビシクロ化合物
WO2009158375A1 (en) * 2008-06-25 2009-12-30 Abbott Laboratories Aza-cylic indole- 2 -carboxamides and methods of use thereof
US8642638B2 (en) 2008-11-19 2014-02-04 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
PH12012502252A1 (en) 2010-05-17 2022-10-05 Envivo Pharmaceuticals Inc A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
RU2635522C2 (ru) 2012-05-08 2017-11-13 Форум Фармасьютикалз, Инк. Способы поддержания, лечения или улучшения когнитивной функции

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8701682A (nl) * 1986-07-30 1988-02-16 Sandoz Ag Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
EP0289170B1 (en) * 1987-04-25 1993-06-23 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben

Also Published As

Publication number Publication date
IE921488A1 (en) 1992-11-18
NO921831L (no) 1992-11-11
CS130592A3 (en) 1992-11-18
HU208136B (en) 1993-08-30
DE4115215A1 (de) 1992-11-12
EP0512350A2 (de) 1992-11-11
KR920021507A (ko) 1992-12-18
HUT61541A (en) 1993-01-28
NO921831D0 (no) 1992-05-08
ZA923351B (en) 1993-01-27
CA2068238A1 (en) 1992-11-11
JPH05155886A (ja) 1993-06-22
AU1604492A (en) 1992-11-12
MX9202152A (es) 1992-11-01
HU9201550D0 (en) 1992-07-28
TW221807B (enExample) 1994-03-21
EP0512350A3 (en) 1992-12-16

Similar Documents

Publication Publication Date Title
PL295961A1 (en) Method of obtaining novel banzanilide derivatives
PL295892A1 (en) Method of obtaining novel derivatives of taxole
PL291463A1 (en) Method of obtaining novel derivatives of 3-amidopyrazole
PL292669A1 (en) Method of obtaining novel derivatives of -ketoacetamide
PL297030A2 (en) Method of obtaining novel derivatives of inidazopyridine
PL294457A2 (en) Method of obtaining novel 3-(indolocarbonamide-2)-quinuclidines
EP0545718A3 (en) Method of making bone-implants
PL288598A1 (en) Method of obtaining novel derivatives of azaoxyindole
PL291562A1 (en) Method of obtaining novel heterodiazepins
PL290856A1 (en) Method of obtaining Ÿ-lactames
PL294309A1 (en) Method of obtaining novel derivatives of 2-amino-pyrimidincarbonamide-4
PL294561A1 (en) Method of obtaining novel azetydine derivatives
PL296865A2 (en) Method of obtaining novel benzofuranes
PL288627A1 (en) Method of obtaining pentafluorodichloropropanes
PL295042A1 (en) Method of obtaining novel derivatives of 2-piperidinylpyrimidin-4-carboxyamide
PL289892A1 (en) Method of obtaining novel 4-(3-(4-oxothoazolydinyl)) butymylamines
PL292497A1 (en) Method of obtaining novel 3h-purines
PL283907A1 (en) Method of obtaining oligoestrols
EP0505002A3 (en) Method of preparing polyethercyclicpolyols
EP0505000A3 (en) Method of preparing polyethercyclicpolyols
PL292950A1 (en) Method of obtaining trialkylogalium
PL289716A1 (en) Method of obtaining buprenophine
PL287126A1 (en) Method of obtaining pululane
PL292308A1 (en) Method of obtaining tioxane
PL289736A1 (en) Method of obtaining hydridocarbonyltristriphenyl-phosphinorhodium