PL2918288T3 - Zastosowanie antagonistów TGF beta do leczenia niemowląt obarczonych ryzykiem rozwinięcia dysplazji oskrzelowo-płucnej - Google Patents

Zastosowanie antagonistów TGF beta do leczenia niemowląt obarczonych ryzykiem rozwinięcia dysplazji oskrzelowo-płucnej

Info

Publication number
PL2918288T3
PL2918288T3 PL15154393T PL15154393T PL2918288T3 PL 2918288 T3 PL2918288 T3 PL 2918288T3 PL 15154393 T PL15154393 T PL 15154393T PL 15154393 T PL15154393 T PL 15154393T PL 2918288 T3 PL2918288 T3 PL 2918288T3
Authority
PL
Poland
Prior art keywords
risk
tgf beta
bronchopulmonary dysplasia
beta antagonists
treat infants
Prior art date
Application number
PL15154393T
Other languages
English (en)
Inventor
James B. Streisand
Jesse D. Roberts
Original Assignee
Genzyme Corporation
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corporation, The General Hospital Corporation filed Critical Genzyme Corporation
Publication of PL2918288T3 publication Critical patent/PL2918288T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL15154393T 2006-10-03 2007-10-03 Zastosowanie antagonistów TGF beta do leczenia niemowląt obarczonych ryzykiem rozwinięcia dysplazji oskrzelowo-płucnej PL2918288T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82793306P 2006-10-03 2006-10-03
EP15154393.1A EP2918288B1 (en) 2006-10-03 2007-10-03 Use of TGF beta antagonists to treat infants at risk of developing bronchopulmonary dysplasia
EP07867199.7A EP2083863B1 (en) 2006-10-03 2007-10-03 Antibodies to tgf-beta for use in the treatment of infants at risk of developing bronchopulmonary dysplasia

Publications (1)

Publication Number Publication Date
PL2918288T3 true PL2918288T3 (pl) 2018-02-28

Family

ID=39217964

Family Applications (2)

Application Number Title Priority Date Filing Date
PL15154393T PL2918288T3 (pl) 2006-10-03 2007-10-03 Zastosowanie antagonistów TGF beta do leczenia niemowląt obarczonych ryzykiem rozwinięcia dysplazji oskrzelowo-płucnej
PL07867199T PL2083863T3 (pl) 2006-10-03 2007-10-03 Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnej

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL07867199T PL2083863T3 (pl) 2006-10-03 2007-10-03 Przeciwciała przeciwko TGF-beta do stosowania w leczeniu niemowląt obarczonych ryzykiem rozwinięcia się dysplazji oskrzelowo-płucnej

Country Status (10)

Country Link
US (3) US8642034B2 (pl)
EP (3) EP2083863B1 (pl)
CN (2) CN104645328A (pl)
DK (2) DK2083863T3 (pl)
ES (2) ES2647472T3 (pl)
HU (1) HUE035575T2 (pl)
IL (2) IL197797A (pl)
MX (1) MX2009003518A (pl)
PL (2) PL2918288T3 (pl)
WO (1) WO2008060371A1 (pl)

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TWI726870B (zh) 2015-03-04 2021-05-11 美商健臻公司 具有高親和性、結合性及專一性之結合轉形生長因子-β1的scFv-Fc二聚體
TWI733661B (zh) 2015-03-04 2021-07-21 美商健臻公司 以高親合性、結合性及特異性結合轉化生長因子-β1的經修飾IgG抗體
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Also Published As

Publication number Publication date
IL251994B (en) 2021-01-31
IL251994A0 (en) 2017-06-29
EP2083863A1 (en) 2009-08-05
EP2918288A1 (en) 2015-09-16
EP3254696A1 (en) 2017-12-13
CN101553254A (zh) 2009-10-07
EP2083863B1 (en) 2015-03-18
DK2083863T3 (da) 2015-06-22
WO2008060371A1 (en) 2008-05-22
CN104645328A (zh) 2015-05-27
HUE035575T2 (en) 2018-05-28
IL197797A0 (en) 2011-08-01
ES2538265T3 (es) 2015-06-18
US20100008911A1 (en) 2010-01-14
US20140199399A1 (en) 2014-07-17
ES2647472T3 (es) 2017-12-21
US8642034B2 (en) 2014-02-04
US20170233464A1 (en) 2017-08-17
PL2083863T3 (pl) 2015-08-31
WO2008060371A8 (en) 2008-07-10
DK2918288T3 (da) 2017-11-27
IL197797A (en) 2017-05-29
EP2918288B1 (en) 2017-08-16
MX2009003518A (es) 2009-08-25

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