PL2758394T3 - Związki heteroarylowe jako ligandy receptora 5-HT4 - Google Patents
Związki heteroarylowe jako ligandy receptora 5-HT4Info
- Publication number
- PL2758394T3 PL2758394T3 PL12716662T PL12716662T PL2758394T3 PL 2758394 T3 PL2758394 T3 PL 2758394T3 PL 12716662 T PL12716662 T PL 12716662T PL 12716662 T PL12716662 T PL 12716662T PL 2758394 T3 PL2758394 T3 PL 2758394T3
- Authority
- PL
- Poland
- Prior art keywords
- receptor ligands
- heteroaryl compounds
- heteroaryl
- compounds
- ligands
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Semiconductor Integrated Circuits (AREA)
- Structures Or Materials For Encapsulating Or Coating Semiconductor Devices Or Solid State Devices (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3203CH2011 | 2011-09-19 | ||
| PCT/IN2012/000011 WO2013042135A1 (en) | 2011-09-19 | 2012-01-05 | Heteroaryl compounds as 5-ht4 receptor ligands |
| EP12716662.7A EP2758394B1 (en) | 2011-09-19 | 2012-01-05 | Heteroaryl compounds as 5-ht4 receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2758394T3 true PL2758394T3 (pl) | 2015-08-31 |
Family
ID=46001349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12716662T PL2758394T3 (pl) | 2011-09-19 | 2012-01-05 | Związki heteroarylowe jako ligandy receptora 5-HT4 |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US9079894B2 (pl) |
| EP (1) | EP2758394B1 (pl) |
| JP (1) | JP5714729B2 (pl) |
| KR (1) | KR101551481B1 (pl) |
| CN (1) | CN103380131B (pl) |
| AP (1) | AP3307A (pl) |
| AU (1) | AU2012311057B2 (pl) |
| BR (1) | BR112014001083B8 (pl) |
| CA (1) | CA2823548C (pl) |
| CY (1) | CY1116173T1 (pl) |
| DK (1) | DK2758394T3 (pl) |
| EA (1) | EA022374B1 (pl) |
| ES (1) | ES2531885T3 (pl) |
| HK (1) | HK1187340A1 (pl) |
| HR (1) | HRP20150229T1 (pl) |
| IL (1) | IL231305A0 (pl) |
| ME (1) | ME02107B (pl) |
| MX (1) | MX337721B (pl) |
| PL (1) | PL2758394T3 (pl) |
| PT (1) | PT2758394E (pl) |
| RS (1) | RS53940B1 (pl) |
| SG (1) | SG2014003560A (pl) |
| SI (1) | SI2758394T1 (pl) |
| SM (1) | SMT201500087B (pl) |
| WO (1) | WO2013042135A1 (pl) |
| ZA (1) | ZA201309100B (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012267797A1 (en) * | 2011-06-07 | 2014-01-09 | Sumitomo Dainippon Pharma Co., Ltd. | Indazole- and pyrrolopyridine-derivative and pharmaceutical use thereof |
| CN105120851A (zh) * | 2013-04-05 | 2015-12-02 | Abc生物科学公司 | 用于医疗用途，具体为用于治疗与氧化应激相关的疾病或者炎症和用于保存或者洗涤器官的barettin及其衍生物 |
| BR112016013974B1 (pt) * | 2013-12-16 | 2022-11-22 | Suven Life Sciences Limited | Composto, composição farmacêutica, uso da composição farmacêutica e uso do composto |
| WO2016027277A1 (en) * | 2014-08-16 | 2016-02-25 | Suven Life Sciences Limited | Process for large scale production of 1-isopropyl-3-{5- [1-(3-methoxypropyl) piperidin-4-yl]-[1,3,4]oxadiazol-2-yl}- 1h-indazole oxalate |
| US9957257B2 (en) * | 2015-02-13 | 2018-05-01 | Suven Life Sciences Limited | Amide compounds as 5-HT4 receptor agonists |
| CN107540568A (zh) * | 2017-08-25 | 2018-01-05 | 许昌恒生制药有限公司 | 一种乙氧酰胺苯甲酯的制备方法 |
| EA202191044A1 (ru) * | 2018-10-18 | 2021-07-13 | Сувен Лайф Сайенсиз Лимитед | Новые применения 5-ht4 рецепторного агониста |
| JP2022534425A (ja) | 2019-05-31 | 2022-07-29 | イケナ オンコロジー， インコーポレイテッド | Ｔｅａｄ阻害剤およびその使用 |
| CN110746450A (zh) * | 2019-09-17 | 2020-02-04 | 济南康和医药科技有限公司 | 一种贝前列素钠关键中间体的合成方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2363492A (en) * | 1991-08-03 | 1993-03-02 | Smithkline Beecham Plc | 5-ht4 receptor antagonists |
| TW360653B (en) * | 1995-03-01 | 1999-06-11 | Janssen Pharmaceutica Nv | A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition |
| JP4263240B2 (ja) * | 1995-11-09 | 2009-05-13 | サノフィ−アベンティス | ５−フェニル−３−（ピペリジン−４−イル）−１，３，４−オキサジアゾール−２（３ｈ）−オン誘導体、及びその５−ｈｔ４又はｈ３レセプターリガンドとしての用途 |
| GB0115862D0 (en) * | 2001-06-28 | 2001-08-22 | Smithkline Beecham Plc | Compounds |
| ES2338882T3 (es) | 2003-11-24 | 2010-05-13 | Pfizer, Inc. | Compuestos de acido quinolona-carboxilico que tienen actividad agonista del receptor 5-ht4. |
| BRPI0607456A2 (pt) * | 2005-02-22 | 2009-09-08 | Pfizer | derivados de oxindol como agonistas do receptor 5ht4 |
| WO2006090224A1 (en) | 2005-02-25 | 2006-08-31 | Pfizer Japan Inc. | Benzisoxazole derivatives |
| CA2615611C (en) | 2005-07-22 | 2011-09-27 | Pfizer Inc. | Indazole derivatives |
| BRPI0620146A2 (pt) * | 2005-12-23 | 2011-11-01 | Hoffmann La Roche | derivados de aril-isoxazolo-4-il-oxadiazol, processo para a preparação dos referidos derivados, medicamento que os contém e usos de um desses derivados |
| US20080167286A1 (en) * | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| US20080255203A1 (en) * | 2007-04-12 | 2008-10-16 | Abbott Laboratories | Heterocyclic compounds and their methods of use |
| ES2542551T3 (es) * | 2009-03-09 | 2015-08-06 | Glaxo Group Limited | 4-Oxadiazol-2-il-indazoles como inhibidores de PI3 cinasas |
-
2012
- 2012-01-05 CA CA2823548A patent/CA2823548C/en active Active
- 2012-01-05 US US13/982,486 patent/US9079894B2/en active Active
- 2012-01-05 BR BR112014001083A patent/BR112014001083B8/pt not_active IP Right Cessation
- 2012-01-05 WO PCT/IN2012/000011 patent/WO2013042135A1/en active Application Filing
- 2012-01-05 EA EA201391056A patent/EA022374B1/ru unknown
- 2012-01-05 PT PT127166627T patent/PT2758394E/pt unknown
- 2012-01-05 AP AP2013007301A patent/AP3307A/xx active
- 2012-01-05 KR KR1020137020582A patent/KR101551481B1/ko active IP Right Grant
- 2012-01-05 AU AU2012311057A patent/AU2012311057B2/en active Active
- 2012-01-05 EP EP12716662.7A patent/EP2758394B1/en active Active
- 2012-01-05 DK DK12716662.7T patent/DK2758394T3/en active
- 2012-01-05 MX MX2013014577A patent/MX337721B/es active IP Right Grant
- 2012-01-05 ME MEP-2015-47A patent/ME02107B/me unknown
- 2012-01-05 PL PL12716662T patent/PL2758394T3/pl unknown
- 2012-01-05 SI SI201230163T patent/SI2758394T1/sl unknown
- 2012-01-05 SG SG2014003560A patent/SG2014003560A/en unknown
- 2012-01-05 ES ES12716662.7T patent/ES2531885T3/es active Active
- 2012-01-05 JP JP2013554062A patent/JP5714729B2/ja active Active
- 2012-01-05 RS RS20150234A patent/RS53940B1/en unknown
- 2012-01-05 CN CN201280009072.1A patent/CN103380131B/zh active Active
-
2013
- 2013-12-04 ZA ZA2013/09100A patent/ZA201309100B/en unknown
-
2014
- 2014-01-10 HK HK14100305.4A patent/HK1187340A1/zh unknown
- 2014-03-04 IL IL231305A patent/IL231305A0/en active IP Right Grant
-
2015
- 2015-02-26 HR HRP20150229AT patent/HRP20150229T1/hr unknown
- 2015-03-30 CY CY20151100308T patent/CY1116173T1/el unknown
- 2015-04-09 SM SM201500087T patent/SMT201500087B/xx unknown
- 2015-06-10 US US14/735,237 patent/US9636335B2/en active Active
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