PL2748179T3 - Oczyszczanie białka metodą anionowej chromatografii jonowymiennej - Google Patents
Oczyszczanie białka metodą anionowej chromatografii jonowymiennejInfo
- Publication number
- PL2748179T3 PL2748179T3 PL12770496T PL12770496T PL2748179T3 PL 2748179 T3 PL2748179 T3 PL 2748179T3 PL 12770496 T PL12770496 T PL 12770496T PL 12770496 T PL12770496 T PL 12770496T PL 2748179 T3 PL2748179 T3 PL 2748179T3
- Authority
- PL
- Poland
- Prior art keywords
- anion exchange
- exchange chromatography
- protein purification
- purification
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161547579P | 2011-10-14 | 2011-10-14 | |
| PCT/EP2012/070257 WO2013053887A1 (en) | 2011-10-14 | 2012-10-12 | Protein purification by anion exchange chromatography |
| EP12770496.3A EP2748179B1 (en) | 2011-10-14 | 2012-10-12 | Protein purification by anion exchange chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2748179T3 true PL2748179T3 (pl) | 2022-04-11 |
Family
ID=47010608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12770496T PL2748179T3 (pl) | 2011-10-14 | 2012-10-12 | Oczyszczanie białka metodą anionowej chromatografii jonowymiennej |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10378004B2 (pl) |
| EP (1) | EP2748179B1 (pl) |
| JP (2) | JP6236008B2 (pl) |
| AU (1) | AU2012322948B2 (pl) |
| ES (1) | ES2908920T3 (pl) |
| HK (1) | HK1198588A1 (pl) |
| LT (1) | LT2748179T (pl) |
| PL (1) | PL2748179T3 (pl) |
| WO (1) | WO2013053887A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2563805T (pt) | 2010-04-29 | 2020-05-18 | Baxalta Inc | Método de purificação de proteínas que se ligam a catiões divalentes em resina de permuta aniónica |
| PL2748179T3 (pl) | 2011-10-14 | 2022-04-11 | Takeda Pharmaceutical Company Limited | Oczyszczanie białka metodą anionowej chromatografii jonowymiennej |
| WO2013053888A1 (en) | 2011-10-14 | 2013-04-18 | Baxter International Inc. | Protein purification by anion exchange chromatography |
| DK2970376T3 (en) * | 2013-03-15 | 2018-07-02 | Baxalta Inc | PURIFICATION PROCEDURE FOR VITAMIN K-DEPENDENT PROTEINS BY ANION EXCHANGE CHROMATOGRAPHY |
| TWI684599B (zh) * | 2014-08-12 | 2020-02-11 | 美商巴克斯歐塔公司 | 因子ｘ活化 |
| AU2017381677B2 (en) | 2016-12-22 | 2019-10-03 | Km Biologics Co., Ltd. | Chromatographic method for collecting blood coagulation factor VII with high yield |
| WO2022172284A1 (en) * | 2021-02-11 | 2022-08-18 | Gennova Biopharmaceuticals Ltd. | Purification of a therapeutic protein |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0317376B2 (fr) | 1987-10-23 | 1996-04-03 | Centre Regional De Transfusion Sanguine De Lille | Préparation de concentré de facteur IX humain de haute pureté et d'autres protéines plasmatiques |
| US4981952A (en) * | 1988-10-04 | 1991-01-01 | Eli Lilly And Company | Method for the purification of vitamin K-dependent proteins |
| WO1998035689A1 (en) | 1997-02-14 | 1998-08-20 | American Red Cross | Expression of active human factor ix in mammary tissue of transgenic animals |
| ES2152953T3 (es) * | 1992-08-27 | 2001-02-16 | Sanquin Bloedvoorziening | Anticuerpos especificos para una proteina hemostatica, su utilizacion para aislar proteinas intactas, compuestos hemostaticos carentes de productos de segmentacion proteolitica de la proteina. |
| DE4406515C1 (de) * | 1994-02-28 | 1995-10-19 | Immuno Ag | Verfahren zur Isolierung und Reinigung Vitamin K-abhängiger Proteine |
| US5714583A (en) * | 1995-06-07 | 1998-02-03 | Genetics Institute, Inc. | Factor IX purification methods |
| DE60138111D1 (de) | 2000-07-21 | 2009-05-07 | Chemo Sero Therapeut Res Inst | Verfahren zur reinigung eines kalziumionen-bindenden proteins |
| US20040106779A1 (en) | 2002-12-03 | 2004-06-03 | Bigler Douglas E. | Modified factor IX preparation |
| US20090043080A1 (en) | 2004-09-29 | 2009-02-12 | Novo Nordisk Healthcare A/G | Purification of a Bulk of a Factor VII Polypeptide by Fractionated Elution from an Anion-Exchange Material |
| PL1831242T3 (pl) * | 2004-12-23 | 2013-04-30 | Novo Nordisk Healthcare Ag | Zmniejszanie zawartości zanieczyszczeń białkowych w kompozycjach zawierających zależne od witaminy K białko będące przedmiotem zainteresowania |
| EP1924688A1 (en) | 2005-09-01 | 2008-05-28 | Novo Nordisk Health Care AG | Purification of coagulation factor vii polypeptides |
| WO2007101681A1 (en) | 2006-03-07 | 2007-09-13 | Baxter International Inc | Highly phosphorylated and sulfated recombinant factor ix |
| FR2901796A1 (fr) | 2006-05-31 | 2007-12-07 | Lab Francais Du Fractionnement | Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait |
| FR2901707B1 (fr) | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
| US8399632B2 (en) * | 2007-02-28 | 2013-03-19 | Baxter International Inc. | Method for the purification of recombinant blood coagulation factor IX enriched in sulfated and/or phosphorylated molecules |
| CN104193798A (zh) | 2009-12-18 | 2014-12-10 | Csl有限公司 | 纯化多肽的方法 |
| PT2563805T (pt) | 2010-04-29 | 2020-05-18 | Baxalta Inc | Método de purificação de proteínas que se ligam a catiões divalentes em resina de permuta aniónica |
| WO2013053888A1 (en) | 2011-10-14 | 2013-04-18 | Baxter International Inc. | Protein purification by anion exchange chromatography |
| PL2748179T3 (pl) | 2011-10-14 | 2022-04-11 | Takeda Pharmaceutical Company Limited | Oczyszczanie białka metodą anionowej chromatografii jonowymiennej |
-
2012
- 2012-10-12 PL PL12770496T patent/PL2748179T3/pl unknown
- 2012-10-12 LT LTEPPCT/EP2012/070257T patent/LT2748179T/lt unknown
- 2012-10-12 EP EP12770496.3A patent/EP2748179B1/en active Active
- 2012-10-12 US US14/351,541 patent/US10378004B2/en active Active
- 2012-10-12 JP JP2014535102A patent/JP6236008B2/ja active Active
- 2012-10-12 AU AU2012322948A patent/AU2012322948B2/en active Active
- 2012-10-12 ES ES12770496T patent/ES2908920T3/es active Active
- 2012-10-12 WO PCT/EP2012/070257 patent/WO2013053887A1/en active Application Filing
-
2014
- 2014-12-01 HK HK14112075A patent/HK1198588A1/xx unknown
-
2017
- 2017-05-11 JP JP2017094650A patent/JP6820232B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2748179A1 (en) | 2014-07-02 |
| HK1198588A1 (en) | 2015-04-30 |
| AU2012322948B2 (en) | 2014-11-06 |
| US10378004B2 (en) | 2019-08-13 |
| AU2012322948A1 (en) | 2013-05-16 |
| JP6236008B2 (ja) | 2017-11-22 |
| JP2017160248A (ja) | 2017-09-14 |
| LT2748179T (lt) | 2022-04-11 |
| JP2014530230A (ja) | 2014-11-17 |
| ES2908920T3 (es) | 2022-05-04 |
| US20140302591A1 (en) | 2014-10-09 |
| JP6820232B2 (ja) | 2021-01-27 |
| EP2748179B1 (en) | 2021-12-29 |
| WO2013053887A1 (en) | 2013-04-18 |
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