PL2744831T3 - Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania - Google Patents

Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania

Info

Publication number
PL2744831T3
PL2744831T3 PL12824616T PL12824616T PL2744831T3 PL 2744831 T3 PL2744831 T3 PL 2744831T3 PL 12824616 T PL12824616 T PL 12824616T PL 12824616 T PL12824616 T PL 12824616T PL 2744831 T3 PL2744831 T3 PL 2744831T3
Authority
PL
Poland
Prior art keywords
transferrin
producing
methods
same
fusion protein
Prior art date
Application number
PL12824616T
Other languages
English (en)
Polish (pl)
Inventor
Uday B. Kompella
Robert I. SCHEINMAN
Puneet Tyagi
Original Assignee
The Regents Of The University Of Colorado, A Body Corporate
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of Colorado, A Body Corporate filed Critical The Regents Of The University Of Colorado, A Body Corporate
Publication of PL2744831T3 publication Critical patent/PL2744831T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL12824616T 2011-08-17 2012-08-15 Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania PL2744831T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161524508P 2011-08-17 2011-08-17
PCT/US2012/051013 WO2013025846A2 (en) 2011-08-17 2012-08-15 Transferrin-tumstatin fusion protein and methods for producing and using the same
EP12824616.2A EP2744831B1 (en) 2011-08-17 2012-08-15 Transferrin-tumstatin fusion protein and methods for producing and using the same

Publications (1)

Publication Number Publication Date
PL2744831T3 true PL2744831T3 (pl) 2018-05-30

Family

ID=47715692

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12824616T PL2744831T3 (pl) 2011-08-17 2012-08-15 Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania

Country Status (15)

Country Link
US (1) US9290562B2 (https=)
EP (1) EP2744831B1 (https=)
JP (1) JP6073888B2 (https=)
CN (2) CN110105453A (https=)
AU (1) AU2012296588B2 (https=)
BR (1) BR112014008680A2 (https=)
CA (1) CA2849015C (https=)
DK (1) DK2744831T3 (https=)
ES (1) ES2659161T3 (https=)
NO (1) NO2820418T3 (https=)
PL (1) PL2744831T3 (https=)
PT (1) PT2744831T (https=)
SI (1) SI2744831T1 (https=)
TR (1) TR201802686T4 (https=)
WO (1) WO2013025846A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2995626B1 (en) * 2013-05-06 2018-07-11 China Pharmaceutical University Bifunctional fusion proteins to inhibit angiogenesis in tumour microenvironment and to activate adaptive immune responses and the genes and uses thereof
US20160137717A1 (en) * 2013-06-20 2016-05-19 Gabriela Burian Use of a vegf antagonist in treating choroidal neovascularisation
US11058750B2 (en) 2015-12-03 2021-07-13 Mor Research Applications Ltd. Compositions and methods for treatment of ocular diseases
KR101818151B1 (ko) 2016-03-25 2018-01-16 한국과학기술원 트렌스페린을 포함하는 허혈성망막병증 예방 및 치료용 조성물
CN109053899B (zh) * 2017-12-22 2021-11-16 湖南远泰生物技术有限公司 一种含人转铁蛋白抗原表位序列的嵌合体抗原受体

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672683A (en) 1989-09-07 1997-09-30 Alkermes, Inc. Transferrin neuropharmaceutical agent fusion protein
US20050192242A1 (en) 1995-10-11 2005-09-01 Neal Zane C. Therapeutic fusion protein transgenes
CA2331332A1 (en) * 1998-06-17 1999-12-23 Raghuram Kalluri Anti-angiogenic proteins and methods of use thereof
EP1244701A1 (en) 1999-12-23 2002-10-02 Human Genome Sciences, Inc. Transferrin polynucleotides, polypeptides, and antibodies
AU2002323501C1 (en) 2001-08-30 2010-04-29 Biorexis Technology, Inc Modified transferrin fusion proteins
US8129504B2 (en) * 2001-08-30 2012-03-06 Biorexis Technology, Inc. Oral delivery of modified transferrin fusion proteins
AU2002364586A1 (en) 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
WO2003066824A2 (en) * 2002-02-07 2003-08-14 Aventis Behring Gmbh Albumin-fused kunitz domain peptides
WO2005034877A2 (en) 2003-10-10 2005-04-21 University Of Southern California G-csf transferrin fusion proteins
US20050266067A1 (en) * 2004-03-02 2005-12-01 Shiladitya Sengupta Nanocell drug delivery system
US20080207502A1 (en) * 2004-10-14 2008-08-28 Sopherion Therapeutics, Inc. Anti-Angiogenic Peptides and Methods of Use Thereof
WO2006049983A2 (en) 2004-10-27 2006-05-11 Biorexis Pharmaceutical Corporation Peptide yy modified transferrin fusion proteins
CA2606989A1 (en) * 2005-04-29 2006-11-09 Research Development Foundation Vascular targeting of ocular neovascularization
WO2007087689A1 (en) 2006-02-03 2007-08-09 Crc For Asthma And Airways Ltd A method of modulating cellular activity and agents for use therein
CN101070349B (zh) * 2007-05-22 2010-10-13 山西康宝生物制品股份有限公司 具有选择性杀伤肿瘤新生血管内皮细胞作用的融合蛋白与应用
CN101092452A (zh) * 2007-05-23 2007-12-26 哈尔滨医科大学 肿瘤抑素抗血管生成小分子多肽、融合蛋白及两者制备方法
WO2009086132A2 (en) * 2007-12-20 2009-07-09 University Of Southern California Design of spacers to increase the expression of recombinant fusion proteins
AU2012222833B2 (en) 2011-03-03 2017-03-16 Zymeworks Inc. Multivalent heteromultimer scaffold design and constructs

Also Published As

Publication number Publication date
DK2744831T3 (en) 2018-03-05
JP6073888B2 (ja) 2017-02-01
EP2744831A2 (en) 2014-06-25
NO2820418T3 (https=) 2018-05-05
EP2744831A4 (en) 2015-03-11
AU2012296588A1 (en) 2014-04-03
JP2014526890A (ja) 2014-10-09
CN110105453A (zh) 2019-08-09
US9290562B2 (en) 2016-03-22
BR112014008680A2 (pt) 2017-06-13
CN103998470A (zh) 2014-08-20
US20140179612A1 (en) 2014-06-26
SI2744831T1 (en) 2018-04-30
CA2849015C (en) 2017-08-08
WO2013025846A2 (en) 2013-02-21
CA2849015A1 (en) 2013-02-21
EP2744831B1 (en) 2017-12-06
TR201802686T4 (tr) 2018-03-21
PT2744831T (pt) 2018-03-05
WO2013025846A3 (en) 2013-05-02
AU2012296588B2 (en) 2017-07-27
ES2659161T3 (es) 2018-03-14

Similar Documents

Publication Publication Date Title
PT2697187T (pt) Olefinas e métodos para produção das mesmas
IL240898A0 (en) Antibodies against a5c and methods of using the antibodies
IL233757A0 (en) Anti '1m e-gi antibodies and methods of using them
EP2699719A4 (en) TUBULAR STRUCTURE AND MANUFACTURING METHOD THEREFOR
GB201115529D0 (en) Antibodies, uses and methods
GB201115280D0 (en) Antibodies, uses and methods
ZA201400562B (en) Axmi205 variant proteins and methods for their use
PL2731884T3 (pl) Pojemnik i sposób jego wytwarzania
LT3321287T (lt) Sulieti baltymai ir sudėtinės vakcinos
IL232743A0 (en) anticancer fusion protein
SG10201604332XA (en) Membrane and method for making the same
SG10201500208SA (en) Npp1 fusion proteins
PT2661496T (pt) Proteína de fusão anticancerígena
EP2698386B8 (en) Fusion protein
ZA201405460B (en) Anticancer fusion protein
EP2657337A4 (en) FUSION PROTEIN
ZA201308597B (en) Anticancer fusion protein
EP2718432A4 (en) NUCLEASE FUSION PROTEIN AND USES THEREOF
PL2744831T3 (pl) Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania
ZA201207425B (en) Fusion protein
SG2014008601A (en) Method for producing clean packageing material and the clean packageing material
GB201107189D0 (en) Fusion proteins
GB201114701D0 (en) Fusion proteins
AU2011905145A0 (en) Fusion Protein
AU2011902431A0 (en) Fusion Proteins and Use Thereof