PL2699580T3 - Analogi diazonamidu - Google Patents
Analogi diazonamiduInfo
- Publication number
- PL2699580T3 PL2699580T3 PL12774761T PL12774761T PL2699580T3 PL 2699580 T3 PL2699580 T3 PL 2699580T3 PL 12774761 T PL12774761 T PL 12774761T PL 12774761 T PL12774761 T PL 12774761T PL 2699580 T3 PL2699580 T3 PL 2699580T3
- Authority
- PL
- Poland
- Prior art keywords
- diazonamide analogs
- diazonamide
- analogs
- Prior art date
Links
- 229930188453 diazonamide Natural products 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Photosensitive Polymer And Photoresist Processing (AREA)
- Thermistors And Varistors (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161478059P | 2011-04-22 | 2011-04-22 | |
| EP12774761.6A EP2699580B1 (en) | 2011-04-22 | 2012-04-15 | Diazonamide analogs |
| PCT/US2012/033715 WO2012145255A2 (en) | 2011-04-22 | 2012-04-15 | Diazonamide analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2699580T3 true PL2699580T3 (pl) | 2018-03-30 |
Family
ID=47021791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12774761T PL2699580T3 (pl) | 2011-04-22 | 2012-04-15 | Analogi diazonamidu |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8592469B2 (pl) |
| EP (1) | EP2699580B1 (pl) |
| JP (1) | JP6045083B2 (pl) |
| KR (1) | KR101839642B1 (pl) |
| CN (1) | CN103582645B (pl) |
| AU (1) | AU2012245702B2 (pl) |
| BR (1) | BR112013027089A2 (pl) |
| CA (1) | CA2833956C (pl) |
| DK (1) | DK2699580T3 (pl) |
| ES (1) | ES2652444T3 (pl) |
| HR (1) | HRP20171930T1 (pl) |
| HU (1) | HUE037730T2 (pl) |
| IL (1) | IL228985A (pl) |
| LT (1) | LT2699580T (pl) |
| MX (1) | MX351961B (pl) |
| NO (1) | NO2636579T3 (pl) |
| PL (1) | PL2699580T3 (pl) |
| PT (1) | PT2699580T (pl) |
| RU (1) | RU2608308C2 (pl) |
| SG (1) | SG194223A1 (pl) |
| SI (1) | SI2699580T1 (pl) |
| WO (1) | WO2012145255A2 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021130515A1 (en) * | 2019-12-23 | 2021-07-01 | Latvian Institute Of Organic Synthesis | Structurally simplified diazonamide analogs as antimitotic agents |
| WO2025114775A1 (en) * | 2023-11-29 | 2025-06-05 | Latvian Institute Of Organic Synthesis | Macrocyclic tubulin polymerization inhibitors as anticancer agents |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4261989A (en) | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| US5387584A (en) | 1993-04-07 | 1995-02-07 | Pfizer Inc. | Bicyclic ansamycins |
| US5932566A (en) | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
| US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| EP1289989A2 (en) | 2000-06-07 | 2003-03-12 | Lilly Icos LLC | Derivatives of 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione |
| JP2005519848A (ja) | 2000-11-02 | 2005-07-07 | スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ | Ｈｓｐ９０に結合するための小分子組成物 |
| US7022720B2 (en) | 2001-08-24 | 2006-04-04 | Board Of Regents, The University Of Texas System | Synthetic diazonamides as novel anti-mitotic agents |
| US7517895B2 (en) * | 2001-08-24 | 2009-04-14 | Board Of Regents, The University Of Texas System | Synthetic diazonamides |
| EP2145888A1 (en) | 2003-09-18 | 2010-01-20 | Conforma Therapeutics Corporation | Deazapurine derivatives as HSP90-Inhibitors |
| EA013692B1 (ru) * | 2005-10-31 | 2010-06-30 | Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем | Аналог диазонамида а |
| EP2068904B1 (en) | 2007-06-07 | 2012-12-05 | Joyant Pharmaceuticals, Inc. | Methods for preparing diazonamides |
| CN102014632B (zh) * | 2008-04-29 | 2014-05-28 | 焦阳特制药股份有限公司 | 吲哚啉抗癌剂 |
| US8153619B2 (en) * | 2008-05-22 | 2012-04-10 | Joyant Pharmaceuticals, Inc. | Diazonamide analogs |
-
2012
- 2012-04-15 DK DK12774761.6T patent/DK2699580T3/en active
- 2012-04-15 RU RU2013148153A patent/RU2608308C2/ru not_active IP Right Cessation
- 2012-04-15 AU AU2012245702A patent/AU2012245702B2/en not_active Ceased
- 2012-04-15 CA CA2833956A patent/CA2833956C/en not_active Expired - Fee Related
- 2012-04-15 HU HUE12774761A patent/HUE037730T2/hu unknown
- 2012-04-15 WO PCT/US2012/033715 patent/WO2012145255A2/en not_active Ceased
- 2012-04-15 CN CN201280025812.0A patent/CN103582645B/zh not_active Expired - Fee Related
- 2012-04-15 SI SI201231154T patent/SI2699580T1/en unknown
- 2012-04-15 MX MX2013012283A patent/MX351961B/es active IP Right Grant
- 2012-04-15 HR HRP20171930TT patent/HRP20171930T1/hr unknown
- 2012-04-15 US US13/447,259 patent/US8592469B2/en not_active Expired - Fee Related
- 2012-04-15 ES ES12774761.6T patent/ES2652444T3/es active Active
- 2012-04-15 LT LTEP12774761.6T patent/LT2699580T/lt unknown
- 2012-04-15 PL PL12774761T patent/PL2699580T3/pl unknown
- 2012-04-15 KR KR1020137030833A patent/KR101839642B1/ko not_active Expired - Fee Related
- 2012-04-15 SG SG2013078308A patent/SG194223A1/en unknown
- 2012-04-15 EP EP12774761.6A patent/EP2699580B1/en not_active Not-in-force
- 2012-04-15 PT PT127747616T patent/PT2699580T/pt unknown
- 2012-04-15 BR BR112013027089A patent/BR112013027089A2/pt not_active Application Discontinuation
- 2012-04-15 JP JP2014506470A patent/JP6045083B2/ja not_active Expired - Fee Related
-
2013
- 2013-03-04 NO NO13157611A patent/NO2636579T3/no unknown
- 2013-10-21 IL IL228985A patent/IL228985A/en active IP Right Grant
- 2013-11-25 US US14/089,655 patent/US8846734B2/en not_active Expired - Fee Related
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