PL2699240T3 - Pochodne akadezyny, produkty i kompozycje zawierające te związki, ich zastosowanie terapeutyczne i sposób ich syntezy - Google Patents

Pochodne akadezyny, produkty i kompozycje zawierające te związki, ich zastosowanie terapeutyczne i sposób ich syntezy

Info

Publication number
PL2699240T3
PL2699240T3 PL12722749T PL12722749T PL2699240T3 PL 2699240 T3 PL2699240 T3 PL 2699240T3 PL 12722749 T PL12722749 T PL 12722749T PL 12722749 T PL12722749 T PL 12722749T PL 2699240 T3 PL2699240 T3 PL 2699240T3
Authority
PL
Poland
Prior art keywords
same
products
methods
compositions including
therapeutic uses
Prior art date
Application number
PL12722749T
Other languages
English (en)
Inventor
Rachid Benhida
Patrick Auberger
Vincent Malnuit
Mohsine Driowya
Alexandre Puissant
Guillaume Robert
Original Assignee
Univ Nice Sophia Antipolis
Centre Nat Rech Scient
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nice Sophia Antipolis, Centre Nat Rech Scient, Inst Nat Sante Rech Med filed Critical Univ Nice Sophia Antipolis
Publication of PL2699240T3 publication Critical patent/PL2699240T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41921,2,3-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/061,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056Triazole or tetrazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL12722749T 2011-04-18 2012-04-17 Pochodne akadezyny, produkty i kompozycje zawierające te związki, ich zastosowanie terapeutyczne i sposób ich syntezy PL2699240T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1101204A FR2974089B1 (fr) 2011-04-18 2011-04-18 Derives de l'acadesine, produits et compositions les comprenant, leurs utilisations therapeutiques et leurs procedes de synthese.
EP12722749.4A EP2699240B1 (fr) 2011-04-18 2012-04-17 Dérivés de l'acadésine, produits et compositions les comprenant, leurs utilisations thérapeutiques et leurs procédés de synthèse
PCT/FR2012/000147 WO2012143624A2 (fr) 2011-04-18 2012-04-17 Dérivés de l'acadésine, produits et compositions les comprenant, leurs utilisations thérapeutiques et leurs procédés de synthèse

Publications (1)

Publication Number Publication Date
PL2699240T3 true PL2699240T3 (pl) 2015-10-30

Family

ID=46147469

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12722749T PL2699240T3 (pl) 2011-04-18 2012-04-17 Pochodne akadezyny, produkty i kompozycje zawierające te związki, ich zastosowanie terapeutyczne i sposób ich syntezy

Country Status (15)

Country Link
US (1) US9173892B2 (pl)
EP (1) EP2699240B1 (pl)
JP (1) JP2014515026A (pl)
CN (1) CN103619332A (pl)
AU (1) AU2012246159A1 (pl)
BR (1) BR112013026755A2 (pl)
CA (1) CA2832866A1 (pl)
DK (1) DK2699240T3 (pl)
ES (1) ES2544542T3 (pl)
FR (1) FR2974089B1 (pl)
IL (1) IL228812A0 (pl)
PL (1) PL2699240T3 (pl)
PT (1) PT2699240E (pl)
WO (1) WO2012143624A2 (pl)
ZA (1) ZA201307451B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2494744C1 (ru) * 2012-10-31 2013-10-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") Лечебное средство с противоопухолевой активностью на основе акадезина
CN107641141B (zh) * 2017-10-31 2021-03-23 天津大学 糖偶联-1,2,3-三氮唑取代的多环芳烃衍生物及制备方法
CN110372675B (zh) * 2019-07-18 2022-11-08 曲阜师范大学 一种n-1和n2-氧烷基取代1,2,3-三氮唑化合物的选择性制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002951247A0 (en) * 2002-09-06 2002-09-19 Alchemia Limited Compounds that interact with kinases
US8372986B2 (en) * 2005-09-30 2013-02-12 The Scripps Research Institute Ruthenium-catalyzed cycloaddition of alkynes and organic azides
EP1921072A1 (en) * 2006-11-10 2008-05-14 Laboratorios del Dr. Esteve S.A. 1,2,3-Triazole derivatives as cannabinoid-receptor modulators
GB0722077D0 (en) * 2007-11-09 2007-12-19 Smithkline Beecham Corp Compounds
EP2113508A1 (en) * 2008-04-30 2009-11-04 INSERM (Institut National de la Santé et de la Recherche Medicale) Novel triazole nucleoside derivatives, their preparation and their application in therapeutics
WO2011019799A2 (en) * 2009-08-11 2011-02-17 The Scripps Research Institute Copper catalyzed cycloaddition of organic azides and 1-haloalkynes

Also Published As

Publication number Publication date
WO2012143624A2 (fr) 2012-10-26
AU2012246159A1 (en) 2013-10-31
FR2974089A1 (fr) 2012-10-19
ES2544542T3 (es) 2015-09-01
DK2699240T3 (en) 2015-08-24
CN103619332A (zh) 2014-03-05
US20140179626A1 (en) 2014-06-26
JP2014515026A (ja) 2014-06-26
EP2699240A2 (fr) 2014-02-26
AU2012246159A2 (en) 2014-01-23
EP2699240B1 (fr) 2015-05-27
BR112013026755A2 (pt) 2017-08-08
IL228812A0 (en) 2013-12-31
WO2012143624A3 (fr) 2012-12-20
FR2974089B1 (fr) 2014-04-25
ZA201307451B (en) 2014-05-28
PT2699240E (pt) 2015-09-11
US9173892B2 (en) 2015-11-03
CA2832866A1 (fr) 2012-10-26

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