PL2622078T3 - Białko fuzyjne dla ekspresji białka wydzielniczego - Google Patents

Białko fuzyjne dla ekspresji białka wydzielniczego

Info

Publication number
PL2622078T3
PL2622078T3 PL11763647T PL11763647T PL2622078T3 PL 2622078 T3 PL2622078 T3 PL 2622078T3 PL 11763647 T PL11763647 T PL 11763647T PL 11763647 T PL11763647 T PL 11763647T PL 2622078 T3 PL2622078 T3 PL 2622078T3
Authority
PL
Poland
Prior art keywords
protein
secretory
expression
fusion protein
fusion
Prior art date
Application number
PL11763647T
Other languages
English (en)
Inventor
Joen Luirink
Wouter S P Jong
Original Assignee
Abera Bioscience Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abera Bioscience Ab filed Critical Abera Bioscience Ab
Publication of PL2622078T3 publication Critical patent/PL2622078T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL11763647T 2010-09-28 2011-09-28 Białko fuzyjne dla ekspresji białka wydzielniczego PL2622078T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1051000 2010-09-28
EP11763647.2A EP2622078B1 (en) 2010-09-28 2011-09-28 Fusion protein for secretory protein expression
PCT/EP2011/066854 WO2012041899A1 (en) 2010-09-28 2011-09-28 Fusion protein for secretory protein expression

Publications (1)

Publication Number Publication Date
PL2622078T3 true PL2622078T3 (pl) 2015-05-29

Family

ID=44719941

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11763647T PL2622078T3 (pl) 2010-09-28 2011-09-28 Białko fuzyjne dla ekspresji białka wydzielniczego

Country Status (7)

Country Link
US (1) US9322011B2 (pl)
EP (1) EP2622078B1 (pl)
CN (1) CN103228787B (pl)
CA (1) CA2811699C (pl)
ES (1) ES2529442T3 (pl)
PL (1) PL2622078T3 (pl)
WO (1) WO2012041899A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201009861D0 (en) * 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
WO2013151706A2 (en) 2012-04-06 2013-10-10 Cornell University Subunit vaccine delivery platform for robust humoral and cellular immune responses
CA2878800A1 (en) * 2012-07-10 2014-01-16 Transgene Sa Mycobacterial antigen vaccine
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
MX2017015404A (es) * 2015-06-02 2018-05-22 De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport Visualizacion de superficie de antigenos en vesiculas de membrana externa gram-negativas.
EP4524157A3 (en) 2017-10-25 2025-06-18 Abera Bioscience AB Omv display
GB202009411D0 (en) * 2020-06-19 2020-08-05 Prokarium Ltd Autotransporter systems
EP3981879A1 (en) * 2020-10-09 2022-04-13 Stada Arzneimittel Ag Method of producing a recombinant protein in a host cell which has a disabled rhamnose metabolism as well as expression vectors, host cells and recombinant proteins thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000064592A (ko) * 1996-03-15 2000-11-06 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. 재조합단백질용엑스포트시스템
DK1373571T3 (da) * 2001-03-02 2007-04-16 Univ Des Saarlandes Wissens Un Funktionel overfladefremvisning af polypeptider
GB0220199D0 (en) * 2002-08-30 2002-10-09 Univ Utrecht Mutant protein and refolding method
DE20321889U1 (de) * 2002-08-02 2012-03-12 Glaxosmithkline Biologicals S.A. Impfstoffzusammensetzung
AU2003901316A0 (en) 2003-03-21 2003-04-03 The Royal Alexandra Hospital For Children Regulation of cell surface proteins
ATE474595T1 (de) * 2003-10-02 2010-08-15 Glaxosmithkline Biolog Sa B. pertussis antigene und ihre verwendung bei der vakzinierung
JP5173194B2 (ja) * 2003-12-23 2013-03-27 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
ES2301262B1 (es) * 2004-01-14 2009-05-29 Consejo Sup. Investig. Cientificas Generacion de adhesion especifica en bacterias gram negativas mediante el anclaje de monodominos de inmunoglobulinas en su superficie con autotransportadores.
US8029777B2 (en) * 2004-08-13 2011-10-04 Marshall Barry J Helicobacter system and uses thereof
EP1981905B1 (en) * 2006-01-16 2016-08-31 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Chlamydia vaccine
US8293685B2 (en) * 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
KR20120091067A (ko) * 2009-09-09 2012-08-17 오토디스플레이 바이오테크 게엠베하 캐리어로의 재조합 폴리펩티드의 결합 방법
US8771669B1 (en) * 2010-02-09 2014-07-08 David Gordon Bermudes Immunization and/or treatment of parasites and infectious agents by live bacteria
US9365624B2 (en) * 2010-03-11 2016-06-14 Glaxosmithkline Biologicals, S.A. Vaccine
WO2012038508A1 (en) * 2010-09-23 2012-03-29 Autodisplay Biotech Gmbh Surface display of polypeptides containing a metal porphyrin or a flavin

Also Published As

Publication number Publication date
WO2012041899A1 (en) 2012-04-05
ES2529442T3 (es) 2015-02-20
CN103228787B (zh) 2017-06-23
HK1187369A1 (en) 2014-04-04
CN103228787A (zh) 2013-07-31
US20130344099A1 (en) 2013-12-26
EP2622078B1 (en) 2014-11-05
CA2811699C (en) 2019-07-02
EP2622078A1 (en) 2013-08-07
US9322011B2 (en) 2016-04-26
CA2811699A1 (en) 2012-04-05

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