PL2590683T3 - Sposób wytwarzania ligandów beta-amyloidu znakowanych F-18 - Google Patents
Sposób wytwarzania ligandów beta-amyloidu znakowanych F-18Info
- Publication number
- PL2590683T3 PL2590683T3 PL11723186T PL11723186T PL2590683T3 PL 2590683 T3 PL2590683 T3 PL 2590683T3 PL 11723186 T PL11723186 T PL 11723186T PL 11723186 T PL11723186 T PL 11723186T PL 2590683 T3 PL2590683 T3 PL 2590683T3
- Authority
- PL
- Poland
- Prior art keywords
- production
- amyloid beta
- beta ligands
- labeled amyloid
- labeled
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10164950 | 2010-06-04 | ||
| EP11723186.0A EP2590683B1 (en) | 2010-06-04 | 2011-05-30 | Method for production of f-18 labeled amyloid beta ligands |
| PCT/EP2011/058786 WO2011151273A1 (en) | 2010-06-04 | 2011-05-30 | Method for production of f-18 labeled amyloid beta ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2590683T3 true PL2590683T3 (pl) | 2018-05-30 |
Family
ID=44512314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11723186T PL2590683T3 (pl) | 2010-06-04 | 2011-05-30 | Sposób wytwarzania ligandów beta-amyloidu znakowanych F-18 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8981156B2 (pl) |
| EP (1) | EP2590683B1 (pl) |
| JP (2) | JP5869561B2 (pl) |
| KR (1) | KR101906873B1 (pl) |
| CN (1) | CN103415304B (pl) |
| AU (1) | AU2011260411B2 (pl) |
| BR (1) | BR112012030937B1 (pl) |
| CA (1) | CA2801569C (pl) |
| EA (1) | EA022896B1 (pl) |
| ES (1) | ES2655414T3 (pl) |
| HK (1) | HK1188569A1 (pl) |
| MX (1) | MX2012014118A (pl) |
| PL (1) | PL2590683T3 (pl) |
| PT (1) | PT2590683T (pl) |
| SG (1) | SG185786A1 (pl) |
| TW (1) | TWI504414B (pl) |
| WO (1) | WO2011151273A1 (pl) |
| ZA (1) | ZA201209009B (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103328011A (zh) * | 2010-06-04 | 2013-09-25 | 皮拉马影像股份公司 | 生产F-18标记的β-淀粉样蛋白配体的方法 |
| BR112014009013A2 (pt) * | 2011-10-19 | 2017-05-02 | Piramal Imaging Sa | método melhorado para a produção de ligandos aß rotulados por f-18 |
| CN113387927B (zh) * | 2021-06-17 | 2022-10-04 | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 一种用于制备乏氧显像剂的硝基咪唑类衍生物及其制备方法和应用 |
| CN114805190A (zh) * | 2022-06-08 | 2022-07-29 | 吉林大学第一医院 | 一种甲基苯胺类Aβ蛋白显像剂的双柱合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070029035A (ko) | 2004-07-08 | 2007-03-13 | 다이셀 가가꾸 고교 가부시끼가이샤 | 장섬유 강화 수지 구조체용 인취장치 및 이 구조체의제조방법 |
| KR100789847B1 (ko) * | 2004-12-15 | 2007-12-28 | (주)퓨쳐켐 | 알코올 용매하에서 유기플루오로 화합물의 제조방법 |
| SI2213652T1 (sl) * | 2004-12-17 | 2015-03-31 | The Trustees Of The University Of Pennsylvania | Derivati stilbena in njihova uporaba za vezavo in prikaz amiloidnih plakov |
| PT1999109E (pt) | 2006-03-30 | 2012-03-16 | Univ Pennsylvania | Derivados de estirilpiridina e sua utilização para ligação e obtenção de imagens de placas amilóides |
| EP2297070A2 (en) | 2008-07-03 | 2011-03-23 | Bayer Schering Pharma Aktiengesellschaft | Compounds and processes for production of radiopharmaceuticals |
| HUE033649T2 (en) * | 2008-12-31 | 2017-12-28 | Avid Radiopharmaceuticals Inc | Synthesis of 18F-labeled styryl pyridines from tosylate precursors and their stable pharmaceutical preparations |
| US20100292478A1 (en) * | 2009-05-18 | 2010-11-18 | Gachon University Of Medicine & Science Industry- Academic Cooperation Foundation | Process of preparing a radioactive compound containing a fluorine-18 isotope |
| US8968701B2 (en) | 2009-07-10 | 2015-03-03 | Piramal Imaging Sa | Usage of low to medium-pressure liquid chromatography for the purification of radiotracers |
-
2011
- 2011-05-20 TW TW100117865A patent/TWI504414B/zh active
- 2011-05-30 US US13/701,595 patent/US8981156B2/en active Active
- 2011-05-30 BR BR112012030937-4A patent/BR112012030937B1/pt active IP Right Grant
- 2011-05-30 MX MX2012014118A patent/MX2012014118A/es active IP Right Grant
- 2011-05-30 PL PL11723186T patent/PL2590683T3/pl unknown
- 2011-05-30 PT PT117231860T patent/PT2590683T/pt unknown
- 2011-05-30 EP EP11723186.0A patent/EP2590683B1/en active Active
- 2011-05-30 CN CN201180027658.6A patent/CN103415304B/zh active Active
- 2011-05-30 WO PCT/EP2011/058786 patent/WO2011151273A1/en active Application Filing
- 2011-05-30 AU AU2011260411A patent/AU2011260411B2/en active Active
- 2011-05-30 EA EA201201644A patent/EA022896B1/ru not_active IP Right Cessation
- 2011-05-30 JP JP2013512853A patent/JP5869561B2/ja active Active
- 2011-05-30 KR KR1020137000139A patent/KR101906873B1/ko active IP Right Grant
- 2011-05-30 SG SG2012087409A patent/SG185786A1/en unknown
- 2011-05-30 ES ES11723186.0T patent/ES2655414T3/es active Active
- 2011-05-30 CA CA2801569A patent/CA2801569C/en active Active
-
2012
- 2012-11-28 ZA ZA2012/09009A patent/ZA201209009B/en unknown
-
2014
- 2014-02-21 HK HK14101672.7A patent/HK1188569A1/zh unknown
-
2015
- 2015-10-23 JP JP2015208855A patent/JP2016028103A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011260411A1 (en) | 2012-12-20 |
| HK1188569A1 (zh) | 2014-05-09 |
| US20130172620A1 (en) | 2013-07-04 |
| EP2590683A1 (en) | 2013-05-15 |
| EP2590683B1 (en) | 2017-10-18 |
| TWI504414B (zh) | 2015-10-21 |
| EA022896B1 (ru) | 2016-03-31 |
| CA2801569C (en) | 2017-05-09 |
| KR20130136424A (ko) | 2013-12-12 |
| KR101906873B1 (ko) | 2018-10-12 |
| BR112012030937A2 (pt) | 2016-11-01 |
| AU2011260411B2 (en) | 2014-05-08 |
| CN103415304A (zh) | 2013-11-27 |
| JP2013528611A (ja) | 2013-07-11 |
| ES2655414T3 (es) | 2018-02-20 |
| TW201208707A (en) | 2012-03-01 |
| WO2011151273A1 (en) | 2011-12-08 |
| JP2016028103A (ja) | 2016-02-25 |
| CN103415304B (zh) | 2016-01-20 |
| EA201201644A1 (ru) | 2013-06-28 |
| ZA201209009B (en) | 2013-08-28 |
| CA2801569A1 (en) | 2011-12-08 |
| MX2012014118A (es) | 2013-07-03 |
| BR112012030937B1 (pt) | 2020-11-24 |
| SG185786A1 (en) | 2013-01-30 |
| US8981156B2 (en) | 2015-03-17 |
| JP5869561B2 (ja) | 2016-02-24 |
| PT2590683T (pt) | 2018-01-08 |
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