PL2443094T3 - Sposób wytwarzania telmisartanu - Google Patents

Sposób wytwarzania telmisartanu

Info

Publication number
PL2443094T3
PL2443094T3 PL10724533T PL10724533T PL2443094T3 PL 2443094 T3 PL2443094 T3 PL 2443094T3 PL 10724533 T PL10724533 T PL 10724533T PL 10724533 T PL10724533 T PL 10724533T PL 2443094 T3 PL2443094 T3 PL 2443094T3
Authority
PL
Poland
Prior art keywords
telmisartan
preparation
Prior art date
Application number
PL10724533T
Other languages
English (en)
Inventor
Silvo Zupancic
Gregor Sedmak
Franc Vrecer
Original Assignee
Krka Tovarna Zdravil D D Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Tovarna Zdravil D D Novo Mesto filed Critical Krka Tovarna Zdravil D D Novo Mesto
Publication of PL2443094T3 publication Critical patent/PL2443094T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL10724533T 2009-06-19 2010-06-21 Sposób wytwarzania telmisartanu PL2443094T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SI200900169 2009-06-19
SI200900267 2009-09-30
SI200900387 2009-12-18
EP10724533A EP2443094B1 (en) 2009-06-19 2010-06-21 Process for the preparation of telmisartan
PCT/EP2010/058754 WO2010146187A2 (en) 2009-06-19 2010-06-21 Process for the preparation of telmisartan

Publications (1)

Publication Number Publication Date
PL2443094T3 true PL2443094T3 (pl) 2013-08-30

Family

ID=42541571

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10724533T PL2443094T3 (pl) 2009-06-19 2010-06-21 Sposób wytwarzania telmisartanu

Country Status (6)

Country Link
EP (1) EP2443094B1 (pl)
ES (1) ES2415357T3 (pl)
HR (1) HRP20130557T1 (pl)
PL (1) PL2443094T3 (pl)
SI (1) SI2443094T1 (pl)
WO (1) WO2010146187A2 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA025946B1 (ru) 2010-10-27 2017-02-28 Крка, Товарна Здравил, Д. Д., Ново Место Многослойная фармацевтическая композиция, содержащая телмисартан и амлодипин
CN103787982A (zh) * 2012-10-31 2014-05-14 上海特化医药科技有限公司 制备替米沙坦的方法及其中间体
CN109912512B (zh) * 2017-12-13 2023-05-30 上海科胜药物研发有限公司 一种新的替米沙坦杂质化合物及其制备方法和用途

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9210098B (sl) 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
DE19901921C2 (de) 1999-01-19 2001-01-04 Boehringer Ingelheim Pharma Polymorphe von Telmisartan, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung eines Arzneimittels
WO2003007876A2 (en) 2001-06-25 2003-01-30 University Of Massachusetts N-fatty acid-amino acid conjugates and therapeutic uses
CN1204124C (zh) 2001-10-15 2005-06-01 中国科学院上海药物研究所 替米沙坦的一种制备路线
EP1467712B2 (en) 2002-01-16 2011-08-31 Boehringer Ingelheim Pharma GmbH & Co. KG Method of producing a bilayer pharmaceutical tablet comprising telmisartan and hydrochlorothiazide
DE10244681A1 (de) 2002-09-24 2004-04-08 Boehringer Ingelheim International Gmbh Neue feste Telmisartan enthaltende pharmazeutische Formulierungen und deren Herstellung
DE10314702A1 (de) 2003-03-31 2004-10-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von Telmisartan
DE10319450A1 (de) 2003-04-30 2004-11-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung des Telmisartan Natriumsalzes
CN1548421A (zh) 2003-05-22 2004-11-24 上海医药工业研究院 替米沙坦盐及其制备方法
GB2414019A (en) * 2004-05-11 2005-11-16 Cipla Ltd One-step preparation of telmisartan by condensation and hydrolysis
US7943781B2 (en) 2004-10-18 2011-05-17 Dr. Reddy's Laboratories Limited Process for preparing telmisartan
WO2006050509A2 (en) 2004-11-03 2006-05-11 Teva Pharmaceutical Industries Ltd. Amorphous and polymorphic forms of telmisartan sodium
EP1824833A2 (en) 2004-11-11 2007-08-29 LEK Pharmaceuticals D.D. Preparation of telmisartan salts with improved solubility
EA200701159A1 (ru) 2004-12-17 2007-12-28 Бёрингер Ингельхайм Интернациональ Гмбх Комбинированное лекарственное средство, включающее телмисартан и гидрохлортиазид
ITMI20050801A1 (it) 2005-05-03 2006-11-04 Dipharma Spa Procedimento per la preparazione di telmisartan
WO2006136916A2 (en) 2005-06-20 2006-12-28 Glenmark Pharmaceuticals Limited Substantially pure micronized particles of telmisartan and pharmaceutical compositions containing same
MX2008000967A (es) 2005-07-20 2008-03-26 Panacea Biotec Ltd Nueva composicion farmaceutica de forma de dosis de liberacion modificada que comprende inhibidor de enzima ciclooxigenasa.
US8637078B2 (en) 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
US20060264491A1 (en) 2006-06-08 2006-11-23 Chemagis Ltd. Telmisartan production process
WO2007144175A2 (en) 2006-06-16 2007-12-21 Lek Pharmaceuticals D.D. Pharmaceutical composition comprising hydrochlorothiazide and telmisartan
SI22297A (sl) 2006-06-23 2007-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Priprava soli telmisartana
CN101743228B (zh) 2007-07-03 2014-01-29 新梅斯托克尔卡托瓦纳兹德拉韦尔公司 替米沙坦的制备方法

Also Published As

Publication number Publication date
EP2443094B1 (en) 2013-03-20
WO2010146187A3 (en) 2011-02-24
WO2010146187A2 (en) 2010-12-23
ES2415357T3 (es) 2013-07-25
SI2443094T1 (sl) 2013-08-30
HRP20130557T1 (en) 2013-07-31
EP2443094A2 (en) 2012-04-25

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