PL2340307T3 - Dwuniciowe kwasy rybonukleinowe o wytrzymałej budowie fizykochemicznej i wysoce swoistej aktywności biologicznych - Google Patents

Dwuniciowe kwasy rybonukleinowe o wytrzymałej budowie fizykochemicznej i wysoce swoistej aktywności biologicznych

Info

Publication number
PL2340307T3
PL2340307T3 PL09822342T PL09822342T PL2340307T3 PL 2340307 T3 PL2340307 T3 PL 2340307T3 PL 09822342 T PL09822342 T PL 09822342T PL 09822342 T PL09822342 T PL 09822342T PL 2340307 T3 PL2340307 T3 PL 2340307T3
Authority
PL
Poland
Prior art keywords
physico
rugged
double
chemical structure
highly specific
Prior art date
Application number
PL09822342T
Other languages
English (en)
Inventor
William A Carter
David Strayer
Original Assignee
Hemispherx Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemispherx Biopharma Inc filed Critical Hemispherx Biopharma Inc
Publication of PL2340307T3 publication Critical patent/PL2340307T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/17—Immunomodulatory nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL09822342T 2008-10-23 2009-10-23 Dwuniciowe kwasy rybonukleinowe o wytrzymałej budowie fizykochemicznej i wysoce swoistej aktywności biologicznych PL2340307T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19303008P 2008-10-23 2008-10-23
EP09822342.3A EP2340307B1 (en) 2008-10-23 2009-10-23 Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity
PCT/US2009/005797 WO2010047835A2 (en) 2008-10-23 2009-10-23 Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity

Publications (1)

Publication Number Publication Date
PL2340307T3 true PL2340307T3 (pl) 2016-02-29

Family

ID=42119891

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09822342T PL2340307T3 (pl) 2008-10-23 2009-10-23 Dwuniciowe kwasy rybonukleinowe o wytrzymałej budowie fizykochemicznej i wysoce swoistej aktywności biologicznych

Country Status (11)

Country Link
EP (1) EP2340307B1 (pl)
AU (1) AU2009308105B2 (pl)
CA (1) CA2741204A1 (pl)
DK (1) DK2340307T3 (pl)
ES (1) ES2553787T3 (pl)
HR (1) HRP20151331T1 (pl)
HU (1) HUE026718T2 (pl)
PL (1) PL2340307T3 (pl)
PT (1) PT2340307E (pl)
SI (1) SI2340307T1 (pl)
WO (1) WO2010047835A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8722874B2 (en) 2008-10-23 2014-05-13 Hemispherx Biopharma, Inc. Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity
US20100160413A1 (en) * 2008-10-23 2010-06-24 Hemispherx Biopharma, Inc. Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity
CA2802721C (en) * 2010-06-25 2015-08-18 Idera Pharmaceuticals, Inc. Novel agonists of toll-like receptor 3 and methods of their use
US11813279B2 (en) 2018-12-21 2023-11-14 Aim Immunotech Inc. Compositions for cancer therapy and methods
WO2020132560A2 (en) * 2018-12-21 2020-06-25 Aim Immunotech Inc. Compositions and methods for cancer therapy
AU2021211012A1 (en) * 2020-01-24 2022-08-25 Aim Immunotech Inc. Methods, compositions, and vaccines for treating a virus infection
AU2021342585A1 (en) * 2020-09-21 2023-05-25 Aim Immunotech Inc. Compositions and methods for treating cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5258369A (en) 1988-08-29 1993-11-02 Hem Pharmaceuticals Corporation Treatment of chronic cerebral dysfunction by dsRNA methodology
GB0119346D0 (en) * 2001-08-08 2001-10-03 Bioclones Proprietary Ltd Process for the maturation of dendritic cells
WO2006054129A1 (en) * 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
JP2010520284A (ja) * 2007-03-05 2010-06-10 ユタ ステイト ユニバーシティ Ｔｏｌｌ様受容体３（ＴＬＲ３）の限定アゴニスト
CA2690641A1 (en) * 2007-06-18 2008-12-24 Hemispherx Biopharma, Inc. Early intervention of viral infections with immune activators

Also Published As

Publication number Publication date
DK2340307T3 (en) 2015-12-14
CA2741204A1 (en) 2010-04-29
ES2553787T3 (es) 2015-12-11
WO2010047835A3 (en) 2010-08-26
AU2009308105B2 (en) 2016-07-07
EP2340307A4 (en) 2012-05-09
SI2340307T1 (sl) 2016-02-29
HRP20151331T1 (hr) 2016-01-29
PT2340307E (pt) 2015-12-01
HUE026718T2 (en) 2016-07-28
AU2009308105A1 (en) 2010-04-29
EP2340307A2 (en) 2011-07-06
EP2340307B1 (en) 2015-09-09
WO2010047835A2 (en) 2010-04-29

Similar Documents

Publication Publication Date Title
EP2499247A4 (en) NEW DOUBLE-STRANDED RIBONUCLEIC ACIDS WITH INCREASED PHYSICO-CHEMICAL STRUCTURE AND HIGHLY SPECIFIC BIOLOGICAL ACTIVITY
PT3590949T (pt) Ácidos ribonucleicos contendo n1-metilpseudouracilos e suas utilizações
SI2340307T1 (sl) Dvoverižne ribonukleinske kisline z robustno fizikalno-kemijsko strukturo in zelo specifično biološko aktivnostjo
LT2334705T (lt) Biologiniai produktai
GB201014134D0 (en) Methods of RNA aplification in the presence of DNA
IL202345A0 (en) Nucleic acid nanoparticles and uses therefor
EP2321654A4 (en) ACTIVITY STATUS CLASSIFICATION
EP2305805A4 (en) DOUBLE STRANDED POLYNUCLEOTIDE
ZA201104429B (en) Polypeptides with xylanase activity
EP2518147A4 (en) DIACYLGLYCEROLACYLTRANSFERASEGEN AND ITS USE
IL201420A0 (en) Nucleic acid enzymes and complexes and methods for their use
PL2342329T3 (pl) Warianty beta-glukozydazy o polepszonej aktywności i ich zastosowania
EP2382310A4 (en) POLYPEPTIDES WITH XYLANASE ACTIVITY
HK1162851A1 (zh) 脂加氧酶活性降低的大麥及由其製備的飲料
GB0807413D0 (en) Biological products
IL216977A (en) Nucleic acid constructs encoded by selection markers, cells containing them and methods for their use
EP2432780A4 (en) PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL
EP2382311A4 (en) POLYPEPTIDES WITH XYLANASE ACTIVITY
EP2328538A4 (en) BIOLOGICAL RESPONSE BITE RING
ZA201108577B (en) Cellulase variants with improved expression, activity and/or stability, and use thereof
HK1142928A1 (zh) 在經修飾的隨機寡核苷酸的存在下的核酸擴增
EP2358911A4 (en) PRODUCTS AND METHODS FOR QUANTIFICATION OF NUCLEIC ACID
PT2154144E (pt) Oligonucleotídeos e utilização dos mesmos
PL2340306T3 (pl) Kwasy nukleinowe o wzmocnionych właściwościach ekspresji
IL214565A0 (en) Nucleic acids specifically binding with human factor vii/viia and uses thereof